A Taxonomy of Industries Based on Knowledge Flow Structure

With the advent of the knowledge-based economy, the inter-industrial flow of technological knowledge is reckoned as the principal determinant of national competitiveness. The mode of knowledge flows, however, is intractably complex. Taking it as a network, this paper aims at providing an inductive taxonomy of industries based on the knowledge flow structure and thus identifying the user-supplier relationship among industries in terms of knowledge diffusion. Some proxy indexes are developed first to measure the knowledge flows, then the interactive mechanism among industries is investigated by the network analysis and eventually a taxonomy of industries is presented according to the characteristics of respective industries. The taxonomic approach highlights the importance of inter-industrial knowledge management system that facilitates knowledge flows across industries based on the idiosyncratic features of respective industries.     

Cost analysis for different sequential treatment regimens for metastatic renal cell carcinoma in China

Abstract

Purpose: Targeted therapies, including sunitinib, sorafenib, axitinib, and everolimus, have recently become the mainstay for the treatment of metastatic renal cell carcinoma (mRCC). The objective of this study was to estimate the costs of sequential treatment regimens for mRCC and associated adverse events (AEs) from the Chinese payers’ perspective.

Methods: Key inputs included in the calculation were patient population, dosing information, incidence rates and associated costs of Grade 3/4 AEs, treatment costs (including drug discount programs), and patients’ progression-free survival (PFS) as a proxy for length of treatment. To calculate PFS, this study identified pivotal clinical trials and generated a reconstructed individual patient data set from the published Kaplan-Meier survival curves. The median PFS from the pooled estimates were used in the calculation. In the base-case scenario, sunitinib was used as first line and the other three therapies were used as second line. Sensitivity analyses were conducted where (1) sorafenib was used as first line, or (2) a third-line therapy was added to the base-case scenario.

Results: In the base case, the cost per patient per treatment month (PPPM) cost was the lowest for sunitinib?+?axitinib among all sequential regimens (¥14,898) and was the highest for sunitinib?+?sorafenib (¥20,103). If sorafenib is used as first line, everolimus had lower per patient per months (PPPM) cost than axitinib (¥17,046 vs ¥23,337), but also had shorter PFS (13.5 months vs 15 months). Second sensitivity analysis with an additional third-line therapy showed consistent results with the base-case scenario; axitinib as second line was the least costly.

Conclusions: This study demonstrates that, for mRCC sequential treatment, sunitinib followed by axitinib generates the highest cost savings from the Chinese payers’ perspective. Future studies are warranted to examine the cost-effectiveness of various mRCC treatment regimens in Chinese populations.     

An evaluation of the validity of the Crowne–Marlowe need for approval scale

Over the past four decades, research has consistently documented negative correlations between the Crowne?CMarlowe (CM) social desirability trait scale and numerous measures of sensitive behaviors, conditions, and opinions. These findings have been interpreted as evidence that persons with self-presentation concerns tend to under-report negative information. In contrast to this classic social desirability interpretation, a second perspective, labeled the true-behavior hypothesis, maintains that these correlations in fact reflect accurate reporting of both sets of variables, suggesting that the CM scale is not a sensitive indicator of the social desirability trait. We test these alternative interpretations by examining data from a community survey that collected both self-reports of cocaine use and the biological specimens necessary to validate the self-reports. In bivariate analyses, the CM scale was found to be associated with the concordance of cocaine use reporting and biological assays in a manner consistent with the classic social desirability hypothesis. The CM scale was not found to be associated with actual cocaine use, as measured by drug test assays, a finding inconsistent with the true-behavior hypothesis. After adjusting for other known correlates of substance use in logistic regression models, the CM scale was not associated with cocaine use under-reporting, nor with actual cocaine use behavior. Until further evidence is available, we conclude that the CM may be a questionable indicator of socially desirable reporting behavior in social surveys.     

The contradictory roles of ambiguity for innovation in an industry: how beneficial are standardisation and classification?

Studies on the influence of ambiguity on innovation show inconsistent understandings: it could be beneficial owing to flexibility, while it might be detrimental owing to distraction of information. Faced with the contradictory understandings, this study examines whether technological standardisation and industry classification could increase innovations of an industry. Using ISO9001 and the SIC codes in Korea from 1998 to 2010, the empirical tests illustrate inverted U-shaped relationships between industry-level innovation and standardisation/classification. Therefore, it is suggested that a moderate degree of standardisation and classification provides a positive infrastructure for innovation by providing the necessary guidelines for a firm's behaviour as well as maintaining its flexibility.     

The timing Of Exchange Regime Collapse Under Capital Controls

This paper investigation the Nature of balance-of payments crises in regimes with capital controls. It extends earlier works on Capital controls by assuming that households manage their consumption and asset portfolios to maximize intertemporal utility. Our main result is that capital controls are effectives in delaying, but not preventing, a breakdown of a fixed exchange rate regime in the presence of money- financed deficits. [F31]     

Industrial relations in Korea

This paper sets out to examine the unique industrial relations systems of East Asian developing countries with special reference to Korea. Following the presentation of a framework of analysis, there is an assessment of environmental conditions, the strategy of the main actors and the changes to them arising from the progress of industrialization. Trade union organizations and collective bargaining in Korea are then examined. This involves special reference to an account of major differences between the Korean system and that of Japan. Outcomes of industrial relations and their recent changes are next discussed. Finally, the analysis is concluded with a review of prospects for the future.     

An assessment of convention tourism's potential contribution to environmentally sustainable growth

The tourism literature contains substantial discussions on how increasing numbers of attendees and conventions at a destination contributes to the local economy, but there is limited research on the environmental impact of the concomitant increases in air and other travel, and other activity increases in energy and other resource use. This research assesses the current environmental position of the convention industry in the United States and formulates suggestions for future direction in regard to “green” concepts by examining and comparing the perceptions, attitudes, and behavioral intentions of three groups of convention stakeholders: convention attendees, meeting planners, and convention suppliers. This empirical study recognizes the critical problem of inadequate understanding of the environmental impact of convention activities and the lack of knowledge regarding ecological convention practices. It shows that the perception of environmental impact among the three groups varies depending on which environmentally friendly practices are available to each group. It discusses the background to – and the implications of – the emotional formation of decisions and self-motivation based on positive attitudes and the strong intention to adopt green management practices agreed to by convention stakeholders.     

Financial incentives and advanced construction procurement systems

Construction clients often use financial incentives to encourage stakeholder motivation and commitment to voluntary higher‐order project goals. Despite the increased use of financial incentives, there is little literature addressing means of optimizing outcomes. Using a case‐study methodology, the examination of a successful Australian construction project demonstrates the features of a positively geared procurement approach that promotes the effectiveness of financial incentives. The research results show that if the incentive system is perceived to be fair and is applied to reward exceptional performance, and not to manipulate, then contractors are more likely to be positively motivated.     

Price negotiation under uncertainty

This paper examines supply contract negotiation when buyer's revenue and seller's cost are uncertain. In these circumstances, both the seller and the buyer have an option to determine when to sell and buy, which may influence negotiation outcomes. Thus, we developed a bilateral negotiation model to derive the optimal selling (buying) rule considering the option. Our results show that the options of waiting to sell and to buy (1) narrow the traditional zone of possible agreement and (2) lower the probability of negotiation agreement. It is also shown that impasses can occur due to uncertainty, even when a purchase price is lower than the buyer's future revenue and higher than the seller's future cost.