From greening to sustaining: Transformational challenges for the firm – a case study of pollution abatement from tanneries in Kasur,Pakistan

This case study of tanneries in Kasur presents an account of industrial transformation of an agrarian society in a developing country, Pakistan, with its effects, efforts to rehabilitate and the difficulties faced in abatement of pollution. The research attempts to respond to the question of the social and economic cost of achieving pollution abatement in Kasur and develop a viable model. The research methods adopted include reviews of secondary data, personal interview and sample survey of tanneries in the study area. The results reveal how people have grappled with the problem of pollution abatement from the tanneries in Kasur and in creating decisive awareness at the local, national and international levels. The transformation of the city from a commercial centre to a semi-industrial tanning centre has led to a loss of 30% cultivable area due to contamination. It is reported that crop yield has dropped by 50% over the past 10 years. The total loss of agricultural income is estimated to be $450 thousand US per annum. The environmental impact of tanneries is highly pronounced in the urban areas around the leather tanning industrial units. Strong protest by the affected population has to some extent forced industrialists to rehabilitate the environment. NGO and the Government are also contributing to this effort. The case study of Kasur presents an example of the community's efforts to mobilize its local, financial and political resources to overcome the environmental hazards, with the associated problems and dilemmas.     

Economic modeling for the US of the cost-efficiency and associated expanded treatment access of conversion to biosimilar pegfilgrastim-bmez from reference pegfilgrastim

Abstract

Aims: For this economic analysis, we aimed to model: (1) the cost-efficiency of prophylaxis with biosimilar pegfilgrastim-bmez for chemotherapy-induced (febrile) neutropenia (CIN/FN) compared to reference pegfilgrastim, and (2) the expanded access to CIN/FN prophylaxis and anti-neoplastic treatment that could be achieved with biosimilar cost-savings on a budget-neutral basis.

Methods: In a hypothetical panel of 20,000 cancer patients receiving CIN/FN prophylaxis and using the average sales price (ASP) for the second quarter of 2019 for reference pegfilgrastim, we: conducted an ex ante simulation from the payer perspective of the cost-savings of 10–100% conversion from reference to biosimilar pegfilgrastim-bmez using drug price discounting ranging from 10–35%; estimated the budget-neutral expanded access to biosimilar pegfilgrastim-bmez enabled by these cost-savings; and estimated the budget-neutral expanded access to anti-neoplastic treatment with pembrolizumab. The simulations were replicated using fourth quarter 2019 wholesale acquisition cost (WAC) for reference pegfilgrastim and biosimilar pegfilgrastim-bmez in a post facto analysis.

Results: In ASP simulations, cost-savings of using pegfilgrastim-bmez over reference pegfilgrastim in a 20,000 patient panel range from $1.3?M (at 15% price discount) to $3?M (35%) at 10% conversion rate and from $6.4?M to $14.9?M, respectively, at 50% conversion. These savings could provide prophylaxis with pegfilgrastim-bmez to an additional 352 (15% discount) to 1,076 patients (35%) at 10% conversion or 1,764–5,384, respectively, at 50% conversion. Alternatively, savings could be reallocated for anti-neoplastic treatment with pembrolizumab to 3 (15% discount) to 9 (35%) patients at 10% conversion or 19–45, respectively, at 50% conversion. When utilizing WAC, cost-savings range from $4.6?M (10% conversion) to $23.1?M (50%) which could provide pegfilgrastim-bmez to an additional 1,174 (10% conversion) to 5,873 patients (50%).

Conclusions: Prophylaxis with biosimilar pegfilgrastim-bmez increases the value of cancer care by generating significant cost-savings that could be reallocated to provide expanded access to CIN/FN prevention and anti-neoplastic therapy on a budget-neutral basis.     

Entrepreneurial intention and startup preparation: A study among business students in Malaysia

Intention, as the starting point of pursuing self-employment and creating new ventures, is crucial before actually establishing a business enterprise. Entrepreneurship is understood to be an essential ingredient for enhancing a country's economic competitiveness, growth, and sustainability while confronting the escalating challenges of globalization, such as increasing unemployment. This study provides empirical evidence on the factors influencing entrepreneurial intention and startup preparations among university students in Malaysia. The findings provide scholars and academic policymakers with insights into the effectiveness of Malaysia's entrepreneurial education as designed and practiced by public universities. The Malaysian government should apply these findings to fortify existing policies and programs and formulate new ones to support graduate entrepreneurs, while universities and other higher education institutions should provide high-quality entrepreneurial courses and programs to young Malaysians to foster an inclination toward entrepreneurship.     

Pioneering Versus Incremental Innovation: Review and Research Propositions

Marketing's role in supporting a company's efforts to develop pioneering and incremental products can be quite different. Abdul Ali examines published articles and offers a set of propositions to show how several factors influence the product development decision. He cites examples from the business world to illustrate these propositions. This article suggests that a firm should take into account several factors relating to its capabilities, along with various project and market characteristics, in order to decide what products it should develop.     

Teacher opinions regarding the perception management levels of school administrators

The purpose of this research is to determine the levels and use of perception management by school administrators. The study group consists of teachers working in Private Primary School and Secondary Schools affiliated to the Ministry of National Education in Nicosia, the Turkish Republic of Northern Cyprus in the 2016–2017 academic year. The sample of the study is composed of 282 teachers representing the universe selected by the method of easy reachable case sampling. As a means of collecting data in the survey, “Personal Information Form” by Kline (An easy guide to factor analysis, Routledge, New York, 1994) and “Manager Perception Management ent Scale” developed by Uylas (Yönetici Alg? Yönetimi Ölçe?i, Türkiye Ölçme Araçlar? Dizini, 2017a, Okul Yöneticilerinin Sosyal-Duygusal E?itim Liderli?i ve Alg? Yönetimine ?li?kin Ö?retmen Görü?leri, T.C. Abant ?zzet Baysal Üniversitesi, E?itim Bilimleri Enstitüsü, Bolu, 2017b) was used. The obtained data were analyzed in an analysis program. In the research, the values of perception management use levels of managers according to teacher opinions were examined. According to the results and comments obtained from the research, some of the proposals developed for researchers and educators working in the field of education management are as follows. Towards practical; trainings can be given on how school administrators can use perception management for successful perception management practices in educational organizations. In interviews to select school administrators, choosing school administrator with high perception management skills can be prioritized. Towards newstudies; including multidimensional evaluation of all elements of educational organizations such as managers, parents and servants in new researches to be conducted and comparison of teachers ‘and administrators’ views. This study has brought out suggestions that can be implemented in other stages of education.     

Budgeting practices in the Turkish hospitality industry: An exploratory survey in the Antalya region

The present study aims to explore budgeting practices of Turkish hotels in the Antalya region which is the most prominent tourism center of the country. The results indicate that having a budget committee and budget manual are common for Turkish hotels. Secondly, participative budgeting is advocated within the industry. Furthermore, budget period seems dynamic, because hotels state that they revise budgets and make periodic reporting within the budget period. Profitability and cost control are the primary reasons in budget preparation. Finally, budgets are viewed as one of the primary performance indicators.     

Cross-sectional determinants of bank performance under deposit dollarization in emerging markets

Dollar-denominated deposits and loans could increase financial fragility in emerging market banking systems. This currency mismatch does not only increase banks' currency risk when the proportion of dollar-denominated loans with respect to local-denominated loans increases but also it increases their clients' default risk if depreciation occurs. This paper investigates the profitability of 36 dollarized banking systems. Results suggest that after controlling for some macroeconomic and institutional variables, dollarization, as the currency mismatch hypothesis suggests, depresses bank performance and lowers bank profitability. Results also show that the effect of institutions more than offsets the negative impact of dollarization on banks' profitability.     

Experience, information asymmetry, and rational forecast bias

This study examines whether it is ever rational for analysts to post biased estimates and how information asymmetry and analyst experience factor into the decision. Using a construct where analysts wish to minimize their forecasting error, we model forecasted earnings when analysts combine private information with consensus estimates to determine the optimal forecast bias, i.e., the deviation from the consensus. We show that the analyst??s rational bias increases with information asymmetry, but is concavely related with experience. Novice analysts post estimates similar to the consensus but as they become more experienced and develop private information channels, their estimates become biased and deviated from the consensus. Highly seasoned analysts, who have superior analytical skills and valuable relationships, need not post biased forecasts.