In the current article, it is argued that individual differences in imaginative thinking may predict transformational leadership. Transformational leaders create a vision for the future, which they must imagine. Moreover, being able to imagine differences in thinking and behavior may aid in the development of more transformation leaders via guided reflection on their leadership practices. Ultimately, assessment of individual differences in imaginative thinking may be useful in recruitment of leaders. 相似文献
To estimate biologic cost per effectively treated patient with rheumatoid arthritis (RA) using a claims-based algorithm for effectiveness.
Methods:
Patients with RA aged 18–63 years in the IMS PharMetrics Plus database were categorized as effectively treated if they met all six criteria: (1) a medication possession ratio ≥80% (subcutaneous) or at least as many infusions as specified in US labeling (intravenous); (2) no biologic dose increase; (3) no biologic switch; (4) no new non-biologic disease-modifying anti-rheumatic drug; (5) no new or increased oral glucocorticoid; and (6) ≤1 glucocorticoid injection. Biologic cost per effectively treated patient was defined as total cost of the index biologic (drug plus intravenous administration) divided by the number of patients categorized by the algorithm as effectively treated. Similar methods were used for the index biologic in the second year and for a second biologic after a switch.
Results:
Rates that the index biologic was categorized as effective in the first year were 31.0% etanercept (2243/7247), 28.6% adalimumab (1426/4991), 28.6% abatacept (332/1160), 27.2% golimumab (71/261), and 20.2% infliximab (474/2352). Mean biologic cost per effectively treated patient, per the algorithm, was $50,141 etanercept, $53,386 golimumab, $56,942 adalimumab, $73,516 abatacept, and $114,089 infliximab. Biologic cost per effectively treated patient, using this algorithm, was lower for patients who continued the index biologic in the second year and higher after switching.
Conclusions:
When a claims-based algorithm was applied to a large commercial claims database, etanercept was categorized as the most effective and had the lowest estimated 1-year biologic cost per effectively treated patient. This proxy for effectiveness from claims databases was validated against a clinical effectiveness scale, but analyses of the second year or the year after a biologic switch were not included in the validation. Costs of other medications were not included in cost calculations. 相似文献
Haiti, with a forest cover estimated at 3% of all land area, has experienced severe degradation of its natural resources and a significant change in its land cover. While deforestation in Haiti is obviously multifaceted, one issue emerges from previous empirical analysis in explaining deforestation: land tenure. This study focuses on the causes of deforestation in Haiti, particularly in Forêt des Pins Reserve, using the annual average area of cleared forest per household as the dependent variable. Data were collected with the use of a survey instrument administered to 243 farm households in 15 villages inside the Reserve. Tobit Regression results reveal that household size, education of head of the household, land tenure regime, and farm labor are important factors affecting land clearing. 相似文献
Abstract We investigate the origins of identity and the innate proclivity to draw a distinction between ‘insiders’ and ‘outsiders’. We propose an evolutionary explanation: we argue that identity arises because it facilitates survival. In an evolutionary setting we endogenize preferences and demonstrate that the evolutionarily stable preferences fashioned by natural selection would distinguish between insiders and outsiders. We then work out the implications of such preferences in two contemporary scenarios, one entailing rent‐seeking behaviour and the other involving public good provision. Our results are in conformity with empirical evidence. 相似文献
Two aspects of effective rates of assistance for Australian agricultural industries are examined. The long-term rate, rather than the rate for a single year, is determined and a rationale is sought for the pattern of assistance that emerges. Second, the influence of exogenous factors (as represented by changes in world prices) on assistance rates is examined. Assistance elasticities are calculated for the major agricultural commodities and estimates made of the likely change in the pattern of assistance rates from any general world price change. In addition, commodities with assistance rates potentially very different from existing rates are identified. Price transmission elasticities are also derived to indicate the degree of insulation that the various policies provide for each commodity. 相似文献
Concepts from the literature on the relationship between environmental variation and strategic change are used to analyze the effects of deregulation on strategic management in the railroad industry. Specific hypotheses are presented about the impact of regulation and change in regulation on strategy, strategic change and performance. A survey of experts identified the strategies of 27 railroads prior to and after deregulation. Five different railroad strategies and five different kinds of strategic changes are identified and described. Results suggest that most firms changed their strategies in response to environmental variation, and that those that did change their strategics out-performed those that did not. Among the strategic changes, those involving innovation and contingency strategies were found to be the most profitable. Other empirical results are presented and discussed. 相似文献
"The structural change model of the demographic transition developed by Easterlin and others is explored empirically by applying the Brown, Durbin and Evans test of structural change to annual data from the transitions of Sweden, Norway, England and Wales, and Finland. The evidence strongly supports the structural change model over traditional models (based on gradual changes in explanatory variables), indicating a supply response of fertility to declining illness and death during the early stages of transition, and a demand response to the death of children during the latter stages, when families are likely to have achieved desired size." 相似文献
We study a setting in which a principal contracts with an agent to operate a firm over an infinite time horizon when the agent is liquidity constrained and privately observes the sequence of cost realizations. We formulate the principal’s problem as a dynamic program in which the state variable is the agent’s continuation utility, which is naturally interpreted as his equity in the firm. The optimal incentive scheme resembles what is commonly regarded as a sweat equity contract, with all rents back loaded. Payments begin when the agent effectively becomes the owner, and from this point on, all production is efficient. These features are shown to be similar to features common in real‐world work‐to‐own franchising agreements and venture capital contracts.相似文献