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51.
The hypercube is a spatially distributed queuing model based on Markovian analysis approximations, used to analyze the configuration and operation of server-to-customer emergency systems. In the present study we adapted the model to analyze emergency medical systems (EMS) on highways, which operate within particular dispatching policies. The study takes into consideration that: the emergency calls are of different types; the servers are distinct (e.g., rescue ambulances, medical vehicles); only certain servers in the system can service calls in a given region (partial backup); and, depending on the type of call, one or more identical or distinct servers are immediately dispatched to service such calls (multiple dispatch). We also consider that the arriving calls take place either along the highway or at the home location of a server – in which case the server does not need to travel to the call location. Finally, we analyzed the computational results of applying such an approach to the case study of an EMS operating on Brazilian highways.  相似文献   
52.
The main focus of the present paper is on the emerging and likely future trade effects of enlargement. Though our particular concern is with Portugal, we set the scene by comparing the trade structures of the 10 countries of Central and Eastern Europe (i.e. the eight CEE accession states plus Bulgaria and Romania) – including an analysis of the individual cases of the Czech Republic, Hungary and Poland – with those of the EU15 as a whole, and with those of the 4 EU cohesion countries. The elimination of trade barriers between incumbents and accession states will have two trade‐related effects on EU incumbents: an increase in bilateral flows with the CEEC and a shift effect as the CEEC displace some incumbent exports to EU markets. The first effect is likely to be strongest for those incumbents for which there is a strong overlap between their export structure and the import structure of the CEEC. Portugal emerges as one of the economies with the least overlap. The displacement effect, we conclude, is likely to be particularly strong in the case of Portugal, given the high degree of similarity between Portuguese exports and those of the CEEC. Portugal appears to be ‘being squeezed from below’ in that, for the majority of its traditional export sectors, the CEEC became progressively more competitive during the second half of the 1990's. Portuguese specialisation was increasingly confined to low‐technology, low‐added‐value sectors with declining demand, as strong FDI inflows to the CEEC led to an increasing preponderance of more dynamic sectors in their export structures. Thus, Portugal is also being squeezed from above. This suggests that there may be substantial industrial disruption, in response to which labour‐market flexibility and dynamic entrepreneurial response is crucial. Intersectoral mobility is generally easier the more highly educated the workforce – an indicator on which Portugal scores poorly. The Portuguese labour market, however, displays a high degree of flexibility, consistent with its long lasting low rate of unemployment. Continued flexibility will help minimise these likely adjustment costs. Besides the trade and industry effects, other topics considered in the paper include the implications of enlargement for Portugal's ability to attract FDI, the likely consequences for Portugal of inward migration from the CEEC to the EU, and the implications of enlargement for Portugal's budgetary relations with the rest of the EU.  相似文献   
53.
Little is known about the form and or magnitude of compensation provided university-based scientists working on firm R&D. This is unfortunate, given the important role that university-based scientists play in R&D, and the growing literature concerning compensation and innovation. This paper sheds some light on these issues by examining the compensation of university-based scientists involved with 52 biotech firms that made an initial public offering between March of 1990 and November of 1992. Although the stock holdings of the university scientists are of particular interest, additional forms of compensation received by the scientists are also examined.We find that approximately 10 percent of the university-based scientists affiliated with these companies hold sufficient options or stock to require disclosure at the time of the public offering. A far larger proportion has an equity position in the firm. In many instances the scientists also receive consulting fees or salary from the firm and enter into licensing agreements with the firm. In addition to providing information concerning the compensation of university-based scientists, the empirical work suggests that the rewards to science can be significantly greater than previous work would suggest.  相似文献   
54.
During the 1990s, foreign direct investment flowed into Latin America at an unprecedented rate. Capital inflows associated with privatizations and private mergers and acquisitions (M&As) rose steeply. Drawing on original firm–level transactions data, this article examines the extent to which UK enterprises participated in the Latin American privatization and private M&A boom. The authors conclude that, relative to their counterparts in many other major industrial countries, UK enterprises adopted a cautious stance, largely eschewing privatization opportunities and concentrating M&A activities on relatively few operations, sectors and countries, in order to strengthen product and market positions. Moreover, the strategic logic guiding the most important corporate acquisitions centred on gaining access to domestic markets rather than attempting to create global export platforms.  相似文献   
55.
In this paper, the links between investment in innovation activities, innovation outputs (technological and non-technological innovation) and productivity in services vis-à-vis the manufacturing sector are explored using innovation survey data from Uruguay. The size of firms, their cooperation in R&D activities, the use of public financial support, patent protection and the use of market sources of information are very important drivers of the decision to invest in innovation activities across sectors. The main determinants of technological and non-technological innovations are the level of investment in innovation activities and the size of the firm. The results indicate that both technological and non-technological innovations are positively associated to productivity gains in services, but non-technological innovations have a more important role. The reverse happens for manufacturing, where technological innovations are more relevant for productivity.  相似文献   
56.
57.
Aims: The objective of this study was to quantify the current and to project future patient and insurer costs for the care of patients with non-small cell lung cancer in the US.

Materials and methods: An analysis of administrative claims data among patients diagnosed with non-small cell lung cancer from 2007–2015 was conducted. Future costs were projected through 2040 based on these data using autoregressive models.

Results: Analysis of claims data found the average total cost of care during first- and second-line therapy was $1,161.70 and $561.80 for patients, and $45,175.70 and $26,201.40 for insurers, respectively. By 2040, the average total patient out-of-pocket costs are projected to reach $3,047.67 for first-line and $2,211.33 for second-line therapy, and insurance will pay an average of $131,262.39 for first-line and $75,062.23 for second-line therapy.

Limitations: Claims data are not collected for research purposes; therefore, there may be errors in entry and coding. Additionally, claims data do not contain important clinical factors, such as stage of disease at diagnosis, tumor histology, or data on disease progression, which may have important implications on the cost of care.

Conclusions: The trajectory of the cost of lung cancer care is growing. This study estimates that the cost of care may double by 2040, with the greatest proportion of increase in patient out-of-pocket costs. Despite the average cost projections, these results suggest that a small sub-set of patients with very high costs could be at even greater risk in the future.  相似文献   

58.
While the post Keynesian literature offers a rather clear concept for growth-oriented policies, it is necessary to adapt them for peripheral emerging economies. We base our analysis of an appropriate Keynesian policy mix for these countries on the concept of currency hierarchy, where the currencies of peripheral emerging economies have a lower liquidity premium than the currencies of advanced economies. The international asymmetry related to the currency hierarchy, amplified by financial globalization, imposes major constraints to the adoption of Keynesian policies for these economies. Under these conditions, we argue that domestic economic policy coordination should lay a major focus on a low policy rate and, especially, a competitive exchange rate for obtaining, at least, a balanced current account, in order to prevent capital flows boom-bust-cycles with subsequent financial crises. We conclude that it is a rather ambitious and long-term goal to climb up the currency hierarchy, especially under the current condition of financial globalization.  相似文献   
59.
This paper addresses the case of the Professional Institute of the Southern Region (IPRES), an institute of higher education in the State University of Morelos, with the aim of showing the measurement results of organizational climate before and after the change of the principal to know some internal features and describe the organizational climate of workers' perception in a transition stage; besides, the influence of the current director's leadership is analyzed in the achievement of organizational goals and how the perception of organizational climate or working environment can be affected by female leadership is also dealt with. In Mexico, there are more and more women running various organizations, including those belonging to the field of education, and universities are no exception. On the other hand, the type of leadership being exercised can promote or hinder the proper performance of the institute and may be a factor of distinction and influence the behavior of those who integrate it; therefore, knowing how it works provides feedback about the processes that determine organizational behavior and the working environment.  相似文献   
60.
Those who use the internet more frequently are more likely to notice a request to participate in a survey than less frequent users. The frequency of internet use is thus likely to affect the likelihood of participation in internet-based surveys. If frequent and infrequent users are different in relevant features, this could influence survey estimates. This study aims to identify which demographic characteristics most differentiate frequent and infrequent users of the internet and whether those distinctions have an influence on substantive responses. The effect of internet usage frequency when conducting internet-based surveys on specific subgroups of the population is also examined. Results suggest that frequent and infrequent users are different both in demographic characteristics and substantive estimates. Differences in substantive estimates are also found when comparing frequent and infrequent users in the 15–24 years subgroup. Weighting can reduce the discrepancies found for most of the substantive estimates, but the differences between frequent and infrequent users remain statistically significant for some specific items.  相似文献   
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