Creating a global health care company

Global pharmaceutical mergers have spread the huge costs of research and enabled companies to sell their products in countries where they previously lacked a presence. Here's how the Beecham-SmithKline Beckman marriage was developed to propel the organization into a position as a worldwide player in the drug industry.     

Assessing black progress: voting and citizenship rights,residency and housing,education

Farley discusses progress US blacks have made in the areas of voting and citizenship rights, residency and housing, and education. A major goal of the civil rights movement was to permit blacks to influence the electoral process in the same manner as whites. Most important in this regard was the Voting Rights Act of 1965; the proportion of southern blacks casting ballots increased sharply since the early 1960s. The Civil Rights Act of 1875 outlawed racial segregation in public accommodations, but by the turn of the century, Jim Crow laws in southern states called for segregation in most public places. Common customs and government policy in the North resulted in similar segregation of blacks from whites. The Montgomery bus boycott and similar protests in dozens of other cities led to enactment of Title II of the Civil Rights Act of 1964, which proscribed such racial practices. By the late 1960s, blacks in all regions could use the same public accommodations as whites. In most metropolitan areas, de facto racial segregation persisted long after the laws were changed. Supreme Court decisions and local open-housing ordinances supported the right of blacks to live where they could afford. However the major change was the Fair Housing Act of 1968, which outlawed racial discrimination in the sale or rental of most housing units. The separation of blacks from whites did not end in the 1970s. Today, in areas which have large black populations, there are many central city neighborhoods and a few in the suburbs which are either all-black or are becoming exclusively black enclaves. Most other neighborhoods have no more than token black populations. Another major effort of civil rights organizations has been the upgrading of housing quality for blacks. By 1980, only 6% of the homes and apartments occupied by blacks lacked complete plumbing facilities (down from 50% in 1940). Unlike the modest changes in residential segregation, racial differences in housing quality have been greatly reduced. By 1960, black students approached parity with whites in terms of measurable aspects of school facilities. In 1940, young blacks averaged about 3 fewer years of educational attainment than whites; the time is nearing when the years of schooling completed by blacks and whites will be the same. In small and medium-sized cities throughout the country, public schools are generally integrated. However, the situation in the largest metropolitan areas is very different. Today, large public schools are segregated, in large part, because blacks and whites live in separate school districts.     

Timing and duration effects in residence histories and other longitudinal data: II. Studies of duration effects in Norway, 1965-1971

The main results of eleven studies of the nature and determinants of the timing of moves and duration of residence effects are presented. The studies (see table 1) illustrate the use of the methodological framework for studying individual histories of the previous article. There are substantial duration of residence effects in most population subgroups, implying that the migration process in non-Markovian at the mocro level and that the semi-Markov model is required. However, characterization of effects and their determinants are shown to depend so heavily on the type of interval and observation scheme used, that only within a comprehensive framework is proper interpretation of empirical results possible.     

DEVIL'S ADVOCACY IN MANAGERIAL DECISION-MAKING

There is some debate about the potential value of using devil's advocates in top-level organizational decision-making. In this paper, the contrasting views on this question are summarized briefly and the field and laboratory research on the devil's advocate and related techniques is discussed. This research is then used as the basis for detailed suggestions on the effective use of devil's advocates in improving managerial decisions.     

On minimum distance estimators for unimodal densities

It is shown that minimum distance estimators for families of unimodal densities are always consistent; the rate of convergence is indicated. An algorithm is proposed for computing the minimum distance estimator for the family of all unimodal densities. References are given to the maximum likelihood method and the kernel method.     

Are robust estimation methods useful in the structural errors-in-variables model?

Summary In this paper it is investigated whether robust estimation procedures for the parameters of a regression model are also applicable when the observations are generated by the errors-in-variables model. Specifically, attention is paid to bounded-influence estimators, i.e. estimators that are constructed in such a way that the influence of a single observation on the outcome of the estimator is bounded. Both the classical errors-in-variables model and models with contaminated observational errors are considered.The authors are indebted to a referee for his valuable comments on an earlier version of this paper.     

Basic Needs and Technology Transfer Issues in the 'New International Economic Order'

A bstract . Developing countries have called for the establishment of a new International Economic Order. New perceptions of development are examined as they relate to haste needs and the transfer of technology within such a framework. The approach seeks to reduce and eventually to eliminate dependence on developed country enterprises, thus allowing developing countries to control their natural resources. It seeks to accelerate self-reliance and to introduce some measure of global management of resources. Technology transferred must be appropriate technology, adapted to local conditions and aimed at meeting specific local needs.     

ON THE FIRST–ORDER EFFICIENCY AND ASYMPTOTIC NORMALITY OF MAXIMUM LIKELIHOOD ESTIMATORS OBTAINED FROM DEPENDENT OBSERVATIONS

Abstract. In this paper we study the first–order efficiency and asymptotic normality of the maximum likelihood estimator obtained from dependent observations. Our conditions are weaker than usual, in that we do not require convergences in probability to be uniform or third–order derivatives to exist.
The paper builds on Witting and Nolle's result concerning the asymptotic normality of the maximum likelihood estimator obtained from independent and identically distributed observations, and on a martingale theorem by McLeish.     

A model of the Dutch labour market (AMO-K)

Summary So far, the labour market has not received any special attention from macro-econometric model builders. In this article an attempt has been made to describe the labour market in detail, paying attention to such important phenomena as the friction between labour supply and demand, the heterogeneity of labour, the dependence of labour supply on the labour-market situation, the Phillips mechanism and the impact of real wages on labour demand. To make it suitable for policy simulations, the model has been extended to a complete macro-econometric model, taking account of the fact that both labour and capital limit the production possibilities.This paper summarises an extensive Dutch report on the construction of a model for the Netherlands labour market. The title of the original report is AMO-K: Een arbeidsmarktmodel met twee categorieën arbeid; (AMO-K, A labour-market model with two categories of labour) ; it was published by the Netherlands Economic Institute (NEI) in Rotterdam in the so-called Olive Series, 1982-2, pp. 403ff. Some details of the model presented in that report were changed after its publication; see G. den Broeder, AMO-K 81-12, Tussenrapport betreffende de verdere ontwikkeling van het arbeidsmarktmodel (Interim report on the further development of the labourmarket model), Rotterdam, September 1983. Since then, only minor changes have been carried through. The model reproduced in this paper is the modified version. The model was developed within the National Programme of Labour-Market Research (NPAO) (now defunct), the NPAO organisation having granted a commission to the NEI in Rotterdam.