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61.
李楠楠 《价值工程》2015,(19):27-29
20世纪90年代至今,一直占据主导地位的2D计算机辅助建筑设计技术已然无法满足如今信息化社会的需要,应运而生的BIM技术不断发展壮大,逐渐成为建设项目设计以及项目管理的主力军,本文旨在研究BIM技术在项目全寿命周期管理中的应用及特点,望引起业内人士对其重视并进行深入学习和探讨。  相似文献   
62.
作为推动国民经济增长和促进社会稳定的基础力量,中小企业在市场中扮演着最活跃的经济主体。与大企业相比,中小企业有其鲜明的成长特征,从动态演进视角选取体量规模、生命周期、要素需求三个维度,系统探讨了中小企业的差异化特征。结论显示:体量规模特征反映在个体与群体以及经济板块之间;生命周期特征体现在死亡陷阱和空间格局演变上;要素需求特征会根据阶段创新内容的不同做出适时调整。  相似文献   
63.
Abstract

Objective: This study aimed to compare the cost-effectiveness of ramucirumab versus placebo for patients with hepatocellular carcinoma who progressed on sorafenib with α-fetoprotein concentrations (AFP) of at least 400?ng/ml in the United States.

Methods: A Markov model was constructed to assess the cost-effectiveness of ramucirumab. Health outcomes were measured as quality-adjusted life years (QALYs). With TreeAge software, the disease process was modeled as three health states: progression-free survival (PFS), progressive disease (PD), and death. Costs were extracted from the REACH-2 trial, and utility was derived from published literature. Incremental cost-effectiveness ratios (ICERs) were calculated to compare ramucirumab with placebo. Probabilistic sensitivity analyses were developed to examine the robustness of the results.

Results: In the base case analysis, ramucirumab therapy had a cost of $55,508.41 and generated 0.54 QALYs, while placebo therapy had a cost of $761.09 and generated 0.47 QALYs, leading to an additional $54,747.32 in costs and 0.07 QALYs. The ICER was $782,104.57 per QALY, which was much higher than the willingness-to-pay threshold of $100,000 per QALY. According to sensitivity analyses, the utility of PD in the two groups was the dominant parameter influencing the ICER.

Conclusion: Although ramucirumab was associated with prolonged survival for patients with advanced hepatocellular carcinoma who progressed on sorafenib treatment with an AFP of at least 400?ng/ml, it is not a cost-effective treatment from a United States payer perspective.  相似文献   
64.
This article provides an in‐depth, longitudinal analysis combining real‐time and retrospective data on a set of Mondragon's industrial cooperatives that are organized as international groups. We examine the life cycle of these international cooperative groups, which is expected to evolve differently to that of small‐ and medium‐sized cooperatives that operate exclusively on a local scale. The article is theoretically informed by the cooperative life cycle theory, as well as by recent insights from the degeneration and regeneration theses. Our analysis yields an intricate picture of the evolution of cooperatives faced with a ‘grow‐or‐die’ dichotomy. On the one hand, our findings reject the highly simplistic and deterministic view of the degeneration thesis by demonstrating that these cooperatives can mobilize resources to revitalize cooperative values and practices. On the other, we find that regeneration may not occur in a consistent, sequential fashion as the previous literature suggests, but rather degenerative and regenerative tendencies can occur simultaneously, even leading to long‐lasting, unresolvable situations. In light of this, the article asks future research to draw on power‐aware and politically informed approaches for further understanding of how cooperatives manage the tensions at each organizational stage of their life cycle, and of which organizational actors benefit, and how, from reversing some degenerative tendencies while maintaining others intact.  相似文献   
65.
This paper investigates the reasons why some technologies, defying general expectations and the established models of technological change, may not disappear from the market after having been displaced from their once-dominant status. Our point of departure is that the established models of technological change are not suitable to explain this as they predominantly focus on technological dominance, giving attention to the technologies that display highest performance levels and gain greatest market share. And yet, technological landscapes are rife with technological designs that do not fulfil these conditions. Using the LP record as an empirical case, we propose that the central mechanism at play in the continuing market presence of once-dominant technologies is the recasting of their technological features from the functional-utilitarian to the aesthetic realm, with an additional element concerning communal interaction among users. The findings that emerge from our quantitative textual analysis of over 200,000 posts on a prominent online LP-related discussion forum (between 2002 and 2010) also suggest that the post-dominance technology adopters and users appear to share many key characteristics with the earliest adopters of new technologies, rather than with late-stage adopters which precede them.  相似文献   
66.
The South African Life Assurance Company (SANLAM) entered global markets after 1990, with varied success. Contextual pressures exerted a ‘push’ on financial services companies, which led to strategic changes in firm strategy, structure and performance. Theories of internationalisation afford more attention to industrial production internationalisation. This article explores the SANLAM experiences with internationalisation since the early 1990s. Initial internationalisation attempts were less successful, leading to strategic business changes, which led to a change in the globalisation strategy and more success in alternative markets. This article explores the different stages of SANLAM’s internationalisation strategy and what determined eventual success. The article contextualises the SANLAM internationalisation strategy by drawing on aspects of the process theory, the Matthews Linkage, Leverage and Learning (LLL) framework, and the Strategy, Structure, Organisation and Performance (SSOP) analytical framework. The SANLAM case underlines the crucial role of tacit knowledge of the host market as prerequisite for successful globalisation strategies of financial services’ firms.  相似文献   
67.
A growing body of risk research shows that risk is content specific. Accordingly, various studies have highlighted some factors that could explain why people’s risk propensity may arise in certain domains of risk (e.g. the financial domain) but not in other domains (e.g. the recreational domain). Until now, no research has examined motivation as a possible correlate of domain-specific risk propensity. On the basis of self-determination theory (SDT), we examined the role of both extrinsic life goals (i.e. superficial goal striving, including fame, money, and physical attraction) and control-orientated personality style (i.e. feeling that one’s behaviors are governed by external contingencies) in the propensity to take risks in various domains (social, ethical, recreational, financial, and health/safety). A community sample of 197 participants completed measures scaled to assess extrinsic life goals, controlled orientation, and domain-specific propensity (DOSPERT). The results showed that pursuing extrinsic goals and being control oriented increased the propensity to take ethical, recreational, financial, and health/safety risks but decreased the propensity to take social risks. In addition, to corroborate that risk propensity is domain specific, these results indicate that superficial life aspiration and sensitivity to social pressures are highly predictive of instrumental risks (e.g. ethical and financial), moderately predictive of health risks, and negatively predictive of ego-threatening risks (e.g. social risk). The results are discussed in light of the domain-specific risk literature and in the perspective of interventions based on SDT.  相似文献   
68.
辛冲  郭鑫 《技术经济》2014,33(10):23-28
分析了基于知识产权的组织间关系网络的基本内涵和构成要素,将基于知识产权的组织间关系网络的生命周期划分为5个阶段——创立阶段、成长阶段、成熟阶段、衰退阶段和解散阶段,具体论述了各阶段的组织间关系网络的演化特征。以对450家企业的深度访谈和问卷调查为基础,通过描述性统计分析、因子分析以及多元方差分析来实证研究目标一致性、信息沟通以及信任等关系属性在各阶段的传递规律。研究结果表明,基于知识产权的组织间关系属性的顶峰阶段并非都出现在关系生命周期的成熟阶段。  相似文献   
69.
Store Brands (SBs) have experienced a strong increase in both value and unit sales internationally during the last decades; thus their market share has been constantly growing. Starting from these considerations, the present work aims at deepening the topic of inter-brand competition within the FMCG market and, in particular, the market share trade-off between Leading National Brands (LNBs) and Store Brands. Our empirical analysis is based on panel data about 322 product categories sold within the Modern Grocery Distribution stores in the 2010–2013 period. Results obtained show: (i) the existence of a relationship between the increase in the LNB-SB price gap and the switching of market share from the former towards the latter; (ii) the consolidation of a change in consumers' purchasing preference in favor of SBs; (iii) the existence of an inverse relationship between the inter-brand competition intensity and the retail branding life cycle evolutionary stage, which is different for each product category.  相似文献   
70.
This study postulates that tourism development (TD) and residents' quality of life (QoL) may have an intrinsically reciprocal relationship. The possible connection between TD and QoL is investigated in the island of Aruba, with economic development as a mediating variable. This investigation contributes to the literature by emphasizing the active role of QoL in the relationship with TD through a subjective well-being approach, and by expanding our understanding of the development concept. The study also advances the scope of tourism theory by presenting new propositions. The methodology consists of applying exploratory and confirmatory factor analyses combined with structural equations modeling. The results suggest that TD has a direct and indirect impact on QoL, and that QoL has an indirect effect on TD, via economic development. These findings provide new insights on the dimensions that shape the link between TD and QoL.  相似文献   
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