企业创新体系研究

企业在市场中的竞争表面上是产品的竞争、技术的竞争,实质上却是隐含于产品、技术背后的企业之间创新能力、创新意识的竞争。“在创新中求发展”已成为企业界的共识。但企业究竟该如何创新,从哪些方面进行创新,成了企业经营中较为困惑的问题。本文在分析创新概念的基础上,提出了企业创新体系的目标及总体构建,并对创新体系的主要内容进行了具体研究,为企业创新实践提供参考。     

中国国内生产总值与教育之间关系的实证分析

本文从柯布-道格拉斯生产函数入手,将劳动力按受教育程度划分为四类分别进行处理。主要就中国国内生产总值(GDP)与各等教育程度劳动力和投资之间关系进行单整和协整检验,并建立误差修正模型(ECM),然后在协整条件下对各等教育程度劳动力与GDP的长、短期关系进行分析。文章的实证结果将为我国有关部门的政策决策提供有力依据。     

A Stochastic Frontier Production Function with Flexible Risk Properties

This paper considers a stochastic frontier production function which has additive, heteroscedastic error structure. The model allows for negative or positive marginal production risks of inputs, as originally proposed by Just and Pope (1978). The technical efficiencies of individual firms in the sample are a function of the levels of the input variables in the stochastic frontier, in addition to the technical inefficiency effects. These are two features of the model which are not exhibited by the commonly used stochastic frontiers with multiplicative error structures.An empirical application is presented using cross-sectional data on Ethiopian peasant farmers. The null hypothesis of no technical inefficiencies of production among these farmers is accepted. Further, the flexible risk models do not fit the data on peasant farmers as well as the traditional stochastic frontier model with multiplicative error structure.     

A review and validation of overall survival extrapolation in health technology assessments of cancer immunotherapy by the National Institute for Health and Care Excellence: how did the initial best estimate compare to trial data subsequently made available?

Background: Validation of overall survival (OS) extrapolations of immune-checkpoint inhibitors (ICIs) during the National Institute for Health and Care Excellence (NICE) Single Technology Assessment (STA) process is limited due to data still maturing at the time of submission. Inaccurate extrapolation may lead to inappropriate decision-making. The availability of more mature trial data facilitates a retrospective analysis of the plausibility and validity of initial extrapolations. This study compares these extrapolations to subsequently available longer-term data.

Methods: A systematic search of completed NICE appraisals of ICIs from March 2000 to December 2017 was performed. A targeted search was also undertaken to procure published OS data from the pivotal clinical trials for each identified STA made available post-submission to NICE. Initial Kaplan-Meier curves and associated extrapolations from NICE documentation were extracted to compare the accuracy of OS projections versus the most mature data.

Results: The review identified 11 STAs, of which 10 provided OS data upon submission to NICE. The extrapolations undertaken considered parametric or piecewise survival models. Additional data cut-offs provided a mean of 18 months of OS beyond the end of the original data. Initial extrapolations typically under-estimated OS from the most mature data cut-off by 0.4–2.7%, depending on the choice of assessment method and use of the manufacturer- or ERG-preferred extrapolation.

Conclusion: Long-term extrapolation of OS is required for NICE STAs based on initial immature OS data. The results of this study demonstrate that the initial OS extrapolations employed by manufacturers and ERGs generally predicted OS reasonably well when compared to more mature data (when available), although on average they appeared to underestimate OS. This review and validation shows that, while the choice of OS extrapolation is uncertain, the methods adopted are generally aligned with later-published follow-up data and appear appropriate for informing HTA decisions.     

逆向选择条件下技术许可中非排他性价格契约研究

通过经典的委托代理理论的应用,文章揭示了一类逆向选择条件下的技术许可中非排他性价格契约理论的内在机理。文章认为,通过针对差的类型的技术使用者的包含可变费用的契约和对好的类型的技术使用者的纯固定费用的契约,可以达到有效的排他性技术许可的目的;但为了有效的激励,技术所有者事前要对好的类型的技术使用者转移一定的信息租。     

全球化背景下以动态比较优势实现产业技术跨越

全球化背景下中国失去了采用传统保护手段来培育动态比较优势，而面对新的机遇和挑战，中国应立足于自身资源禀赋的比较优势，在某些产业的关键环节选择技术跨越来培育动态比较优势；并通过发展高新技术、加强对传统产业的技术改造和提高技术引进效果来有效实施技术跨越，在一定程度上占据国际分工制高点。     

中小企业技术创新的制约因素及其对策研究

中小企业作为推广使用高新技术的第一阵地 ,在技术创新过程中扮演着极其重要的角色。但目前 ,中国中小企业在技术创新活动中却受到诸多因素的制约 ,因此 ,本文在具体剖析了中小企业技术创新障碍的基础上 ,提出了提升其技术创新能力及优化其创新环境的若干对策。     

Pure joint production and international trade: a note

This paper applies the principles of the neo-Ricardian (or Sraffian)theory of international trade to certain joint production systems.It is shown that, in contrast with single-product systems, (i)there is not always a pattern of international specialisation,which would entail the increase of the real wage rate in botheconomies, and (ii) the ‘law of comparative advantage’has no general validity. Furthermore, not only the existenceof such a pattern of specialisation but also the validity ofthis law depend on the values of the variables of distributionof income. The analysis is wholly based on two of the numericalexamples formulated by Bidard in 1997, and further generalisedin an elementary way only when this is considered necessary.     

产品内贸易、技术创新与中国企业可持续发展

在科技革命和经济全球化的共同作用下，特别是随着FDI的增长和跨国公司的全球布点，传统意义上的以商品贸易为基础的国际分工正在被打破，国际分工逐步深入到企业内部，分工方式由产业间分工向产业内部产品分工和要素分工延伸。本文以当前新贸易现象为实践基础，以贸易分工理论为理论基础，初步构建产品内贸易的理论模型及其利益分配机制，从产品内分工视角分析产品内贸易模式对发展中国家贸易条件的影响，并认为中国企业应该在国际分工价值链上进行攀升，进行技术创新，提升在国际贸易中的地位，化比较优势为竞争优势，实现企业的可持续发展。     

Embedded industrial production systems: Lessons from waste management in zinc production

To meet the sustainability challenge private companies must implement corporate strategies and adopt novel technologies. The technical and social embeddedness of industrial production systems, however, complicates these systems' transition towards sustainability. In the paper, mechanisms and conditions are reported for the development and implementation of waste management options in embedded industrial production systems. The focus is on the Dutch zinc production industry, which had to deal with a major waste problem; the generation of jarosite. The industry's options were to increase the jarosite waste storage capacity, to develop a jarosite treatment process or to switch to a zinc-ore of low-iron content whereby no jarosite waste would be generated anymore. Required conditions appeared to be a combination of technological capability and technical embedding and favourable economics. Case study research, however, revealed that adequate stakeholder management is crucial to address social pressure exerted and to obtain external acceptance for any transition strategy. Whilst appropriate, internal technological capabilities are important, effective interactions with and enrolment of various firm-external actors are crucial. In the case of zinc, access to the heterogeneous external actor network was critical for the development of the jarosite treatment solution direction. In conclusion, both the technical, organizational and social embedding of new technologies are crucial for successful implementation.