桥梁病害对桥梁设计的启示分析

现阶段,随着社会经济的飞速发展,道路基础设施的建设速度逐渐加快。同时,随着各种各样桥梁病害问题的出现,对桥梁的承载能力造成了一定程度的影响。因此,及时防治桥梁病害有助于保障桥梁的安全性。论文结合某危桥改造项目,对桥梁的病害展开研讨,对病害的产生原因进行分析,并提供实用性的桥梁设计应对方法,以保证桥梁的耐久性与安全性。     

新冠肺炎疫情、金融市场震荡与金融危机

新型冠状病毒感染肺炎疫情在全球快速蔓延后,美国等国家金融市场出现大幅度震荡,历史罕见。金融市场震荡是疫情影响投资者信心,金融市场本身的风险需要释放,以及经济基本面悲观预期等因素共同作用的结果。目前来看,疫情对实体经济造成冲击,疫情应对情况也在很大程度上决定了金融市场震荡是否演化为全球金融危机,国外金融市场震荡对国内金融市场的传导需要审慎理性处理。     

比利时传染病防控应急体系与应急措施

2019新型冠状病毒肺炎疫情暴发给中国乃至全球公共卫生带来了重大挑战。比利时在传染病防控方面具有丰富的经验。本研究通过检索相关文献及政策资料,回顾比利时针对传染性疾病的应急管理的法律法规、组织框架、经费、应急系统,并以比利时2014年埃博拉疫情防控为例,总结比利时防控传染病政策和措施的成功经验。在此基础上,针对2019冠状病毒提出防治措施建议:设立永久性传染病风险评估工作组;利用大数据构建突发传染病主动防控云平台;定期开展针对突发传染病防控的相关演习等。     

慢性病患者就医行为的文献综述研究

慢性病患者选择就诊方式受到各种因素的影响,本文主要对慢性病患者的就医行为的相关理论和国内外相关研究进行了梳理。     

中小企业集合债券总体信用风险度量研究

中小企业集合债券总体信用风险既包括系统风险产生的周期性违约风险,又包括相互关联关系导致的传染性违约风险。首先通过对因素模型的改进构建模型Ⅰ,研究集合债券的周期性违约风险;在此基础上引入违约传染建立模型Ⅱ,分析违约传染对违约概率及违约相关性的影响,研究集合债券的总体信用风险。最后基于模型Ⅱ进行算例研究,得出结论：企业间的相互关联关系降低了其1次违约概率,增加了其多次违约概率即违约相关性。     

注射用美洛西林钠与胃复安存在配伍禁忌

医师在治疗胃肠科疾病,通常使用注射美洛西林钠进行围术中的抗感染工作,也采用莫非氏管滴入胃复安,但是混合后出现明显的混浊现象,且有絮状沉淀物生成。     

大学生心理疾病产生的原因及对策

21世纪将是心理疾病患者显著增加的年代,心理疾病将成为严重威胁人类和社会稳定的“世纪病”。心理病患者“自杀”的数字也令人吃惊。大学生是心理疾病发生率较多的群体,大学生心理疾病产生的原因是复杂多样的,既有遗传和生理因素,又有社会、学校、家庭及个体心理缺陷等因素。加强对大学生产生心理疾病的原因分析,有助于我们搞好大学生心理教育,帮助大学生增进心理健康。     

沙尘暴对人体健康的影响及防治措施

沙尘暴是我国北方主要的灾害性天气。沙尘天气可造成烟尘与粉尘携带细菌侵入人体呼吸道,沉积在人体的肺部,引发呼吸道疾病并被肺泡吸收进入血液循环,导致其他器官疾病,危害人的身体健康。本文从沙尘暴天气的形成及对人体健康影响入手,提出了指导性的防治措施。     

Unraveling the Genetic Component of Multifactorial Diseases: Dream or Reality

The etiology of many human diseases is complex and very likely involves a combination of genetic and environmental risk factors. A popular strategy to detect genetic risk factors is to perform a systematic screening of the genome searching for linkage. The power of such and approach depends very much on the unknown characteristics of the genetic factors and the main difficulty is to establish a good trade-off between false positives and false negatives. Besides, a precise localisation of the risk factor will generally not be obtained. The set up of a candidate gene stratery is necessary to go further in genetic factor identification. It is likely that for multicfactorioal diseases the only genetic risk factors that can be detected are those with fairly strong effect. Even in that case, it is important to design strategies which increase the power of detection and provide for a better evaluation of the associated risks.     

Healthcare resource utilization by patients with treatment-refractory myasthenia gravis in England

Aims: To examine healthcare resource utilization associated with refractory myasthenia gravis (MG) in England.

Materials and methods: This was a retrospective cohort study of linked data from the Clinical Practice Research Datalink and the Hospital Episode Statistics database collected between 1997 and 2016. Included patients were ≥18?years of age at the index MG diagnosis. Patients with refractory MG were identified using an algorithm based on treatments received. Healthcare resource utilization since the index date was compared between refractory and non-refractory cohorts.

Results: The study included 1149 patients with MG, of whom 66 (5.7%) were refractory. Sex and age at diagnosis did not significantly differ between the refractory and non-refractory cohorts. Rates of healthcare resource utilization per person-year were significantly higher (p?p?Limitations: The algorithm for identifying refractory patients did not include clinical criteria. Also, treatments administered in hospitals or by specialists were not available in the databases.

Conclusions: Patients in England with refractory MG more often visit healthcare providers, are hospitalized and visit an emergency room than patients with non-refractory MG.