Unraveling the Genetic Component of Multifactorial Diseases: Dream or Reality

The etiology of many human diseases is complex and very likely involves a combination of genetic and environmental risk factors. A popular strategy to detect genetic risk factors is to perform a systematic screening of the genome searching for linkage. The power of such and approach depends very much on the unknown characteristics of the genetic factors and the main difficulty is to establish a good trade-off between false positives and false negatives. Besides, a precise localisation of the risk factor will generally not be obtained. The set up of a candidate gene stratery is necessary to go further in genetic factor identification. It is likely that for multicfactorioal diseases the only genetic risk factors that can be detected are those with fairly strong effect. Even in that case, it is important to design strategies which increase the power of detection and provide for a better evaluation of the associated risks.     

高层建筑设计存在的问题

对高层建筑设计中的一些问题和规范中的一些规定进行讨论,并且较好地满足了结构设计要求,实现了建筑与结构的统一,同时对贯彻实施设计规范、标准方面存在的问题提出解决方法,为高层建筑发展创造了前所未有的机遇,高层建筑也成为城市空间中一道独特的风景,对钢筋混凝土建筑设计中的一些问题和规范中的一些规定进行分析,对构造的具体措施进行分析研讨,对高层建筑的因素进行归纳分析。     

“双因素”理论在现代企业人力资源管理中的运用

"双因素"理论在人力资源管理领域具有广阔的使用空间,能有效的激励员工,提高企业的管理效率;利用保健因素如公正公平的工资和津贴,改善工作环境,营造平等和谐的人际关系等将有利于激发员工的工作积极性,但其激励作用是有限的,更重要的是强化员工内在激励,即工作丰富化,给与员工成长机会,组织内部竞争环境等,为员工发展提供良好的平台以及发展空间;运用"双因素"理论时,应该充分了解员工的心理需求,并采用多样化的激励方式,正确区分保健因素和激励因素,防止激励因素转化成保健因素,建立保健和激励因素并重的人员激励制度。     

在健美操教学中,培养学生表现力的分析

本文探讨了影响大学生完成健美操表现力各因素,研究表明:表现力是健美操训练和比赛中一个重要的方面,通过培养身体各部位正确的感知觉练习、理解力的提高、注重交流及对相关艺术门类的学习来提高大学生的健美操表现力。     

山西成家庄煤矿矿井充水因素分析及水害防治措施

矿井水害的预防预报是指查清矿井水文地质条件,对水害做出分析判断。本文以山西成家庄煤矿防治水为例,分析了矿井充水因素,以理论结合实际,为预防矿井水害提供依据。     

影响客运车辆交通安全的因素及其对策

客运车辆安全管理工作是减少交通事故发生和降低人员伤亡及经济损失的有效手段。本文通过分析影响客运车辆安全运行的各种因素,以及部分实际发生的客运车辆交通事故案例,提出了加强和改善客运车辆安全管理的对策和技术措施,对防止或减少客运车辆运营安全事故,提高客运企业安全生产技术和管理水平具有重要意义。     

松动圈理论应用概述

巷道围岩松动圈支护理论在地下工程中的应用日益受到重视。本文对松动圈厚度的测试方法、计算方法进行了阐述与分析。另外还阐述了根据松动圈厚度确定围岩类型和支护方法,提出了今后的研究方向。     

维修过程中的人为因素对飞机安全性的影响

本文简要介绍了维修过程中的人为因素对飞机安全性的影响,分析了研究人为因素的必要性,介绍了目前通用的人为因素理论,并运用案例进行分析和总结,最后介绍了维修单位对减少维修过程中人为因素对飞机安全性影响的方法。     

四川与东盟旅游服务产业内贸易的核心因素初探

中国-东盟自由贸易区的建设为四川旅游业的发展带来了历史性的契机。在此背景下,四川如何抓住机遇,携手东盟,共谋发展成为了一个研究热点。本文以产业内贸易的视角来观察四川与东盟的旅游业发展状况,运用产业内贸易相关理论分析了影响四川与东盟旅游服务产业内贸易的核心因素,提出了区位条件、产品差异化、需求相似、区域经济协作和规模经济可以提升四川与东盟旅游服务产业内贸易水平,双方可以在较高的产业内贸易水平下,实现共赢。     

Business process re-engineering in the logistics industry: a study of implementation,success factors,and performance

As business process re-engineering (BPR) is an important foundation to ensure the success of enterprise systems, this study would like to investigate the relationships among BPR implementation, BPR success factors, and business performance for logistics companies. Our empirical findings show that BPR companies outperformed non-BPR companies, not only on information processing, technology applications, organisational structure, and co-ordination, but also on all of the major logistics operations. Comparing the different perceptions of the success factors for BPR, non-BPR companies place greater emphasis on the importance of employee involvement while BPR companies are more concerned about the influence of risk management. Our findings also suggest that management attitude towards BPR success factors could affect performance with regard to technology applications and logistics operations. Logistics companies which have not yet implemented the BPR approach could refer to our findings to evaluate the advantages of such an undertaking and to take care of those BPR success factors affecting performance before conducting BPR projects.