全开放式泡孔结构的生物质复合材料成型工艺及性能分析

本文以淀粉、植物纤维为对象,提出一种单边空腔自由发泡工艺,可弥补以往生物原料自身属性缺陷,促进复合材料成型工艺与性能提升.在成型工艺方面,主要介绍了整体透气钢镶嵌设计、自动回弹空腔设计以及排气孔设计,有效避免发泡喷料现象产生,实现发泡过程的柔性控制.在性能方面,通过试验探究的方式,重点对复合薄膜的机械性能、防水性能与表...     

Vehicle-to-grid systems for sustainable development: An integrated energy analysis

Vehicle-to-grid (V2G) systems represent a means by which power capacity in parked vehicles can be used to generate electricity for the grid. This paper describes the first detailed and global analysis of the potential of V2G technologies over the long-term (to 2100) using a comprehensive energy-systems model. In this analysis we explore the potential for V2G systems to supply a number of electricity submarkets and concomitantly accelerate the diffusion of advanced vehicle technologies, including hybrid-electric and fuel cell drivetrains. We also examine the potential impact of V2G on the global energy system, particularly in terms of investment in conventional capacity, and the possible role of V2G-enabled vehicles in increasing the market penetration of renewable electricity generation technologies. Importantly, however, V2G technologies represent a paradigm shift in how the energy and mobility markets are related, and a number of possible barriers to the widespread adoption of this technology are also discussed.     

开设光伏专业(太阳电池制造工工种)的实践与探索

太阳电池制造工在光伏企业有着大量的用工需求,但目前职业教育对该工种尚无技能鉴定标准,本文就此问题提出了解决的办法,同时就如何培养出适合企业所需要的复合型人才,做了相应的实践和探索。     

Nanog在肿瘤细胞中表达的Meta分析

目的:研究Nanog蛋白在肿瘤细胞中表达的意义。方法:计算机检索Pub Med、Embase、Cochrane图书馆、CNKI、中国生物医学文献和万方数据库,检索时间均从建库到2014年5月,手工检索相关文献,收集Nanog在肿瘤细胞和正常细胞中表达的随机对照实验。对符合纳入标准的临床研究进行质量评价和资料提取后,采用Rev Man5.2软件进行Meta分析。结果:共纳入9篇原始文献,包括852例组织芯片(其中癌细胞组520例,正常细胞组332例)。Meta分析结果显示:癌细胞组中Nanog蛋白表达风险是正常细胞组的13.78(95%CI:9.60~19.77)倍。敏感性分析Z=14.24,P<0.00001,即分析结果稳定且不存在明显偏倚。结论:Nanog在肿瘤细胞中较正常细胞中显著高表达。     

Treatment patterns,healthcare resource utilization,and costs in patients with acute myeloid leukemia in commercially insured and Medicare populations

Objective: To describe the setting, duration, and costs of induction and consolidation chemotherapy for adults with newly-diagnosed acute myeloid leukemia (AML), who are candidates for standard induction chemotherapy, in the US.

Methods: Adults newly-diagnosed with AML who received standard induction chemotherapy in an inpatient setting were identified from the Truven Health Analytics MarketScan (2006–2015) and SEER-Medicare (2007–2011) databases. Patients were observed from induction therapy start to the first of hematopoietic stem cell transplant, 180 days after induction discharge, health plan enrollment/data availability end, or death. Induction and consolidation chemotherapy were identified using Diagnosis-Related Group codes (chemotherapy with acute leukemia) or procedure codes for AML chemotherapy administration. AML treatment episode setting (inpatient or outpatient), duration, and costs (2015 USD, payers’ perspective) were described for commercially insured patients and Medicare beneficiaries.

Results: In total, 459 commercially insured patients and 563 Medicare beneficiaries (mean age?=?54 and 66 years; 53% and 54% male; respectively) were identified. For induction therapy, mean costs were $145,189 for commercially insured patients and $85,734 for Medicare beneficiaries, and median inpatient duration was 31 days (both). Following induction, 64% of commercially insured patients and 53% of Medicare beneficiaries had ≥1 consolidation cycle; 75% and 65% of consolidation cycles were in an inpatient setting, respectively. For consolidation cycles, in the inpatient setting, mean costs were $28,137 for commercially insured patients and $28,843 for Medicare beneficiaries, median cycle duration was 6 days (both); in the outpatient setting, mean costs were $11,271 for commercially insured patients and $5,803 Medicare beneficiaries, median duration was 5 days (both).

Limitations: Granular information on chemotherapy type administered was unavailable.

Conclusions: This is the first exploratory study providing a complete picture of recent AML treatment patterns and management costs among commercially insured patients and Medicare beneficiaries. There is substantial heterogeneity in the management and costs of AML.     

宽带抗干扰通信系统的跳频同步研究及应用

本文分析了宽带抗干扰跳频通信系统的抗干扰性能，介绍了跳频同步的多种实现方法，提出了一种较好的组合同步方法，并对这种方法的实现原理作了较详细的论述。     

Cost-effectiveness analysis of first-line pembrolizumab treatment for PD-L1 positive,non-small cell lung cancer in China

Purpose: Pembrolizumab was recently approved in several countries as a first-line treatment for patients with PD-L1 positive, non-small cell lung cancer (NSCLC). However, it is expensive. This study aimed to assess the cost-effectiveness of pembrolizumab in treating advanced NSCLC patients with PD-L1 positive cancer in China.

Methods: A Markov model was developed to compare the cost-effectiveness of pembrolizumab with chemotherapy for patients with PD-L1 expression on at least 50% of NSCLC tumor cells. Model inputs for transition probabilities and toxicity were derived from published clinical trial data, while health utilities were estimated from a literature review. Costs for drugs were updated to standard fee data from West China Hospital in 2017. Health outcomes were measured in quality-adjusted life years (QALYs), and cost-effectiveness was measured as the incremental cost-effectiveness ratio (ICER). Sensitivity analyses were conducted to test the robustness of the model.

Results: Pembrolizumab gained 0.45 QALYs at an incremental cost of $46,362 compared to chemotherapy for an ICER of $103,128 per QALY gained. In most scenarios, the ICER exceeded three times the Chinese Gross Domestic Product per capita. Two-way sensitivity analysis showed that, when the utility of the progression-free status increased to the maximal value of 0.845 and the 1?mg dose price decreased to $10.50, the ICER reduced to $25,216/QALY.

Conclusions: Pembrolizumab is not likely to be cost-effective in the treatment of PD-L1 positive, NSCLC for Chinese patients. Less aggressive pricing may increase accessibility for patients in China.     

基于单片机的多功能电子秤的设计

该设计以51系列单片机AT89S52为控制核心,实现电子秤的基本控制功能。为了更好利用AT89S52的资源,系统扩展了电子日历时钟模块及温度检测和语音报数的功能。整个系统结构简单,使用方便,功能齐全,精度高,具有一定的开发价值。     

铜铟镓硒(CIGS)薄膜太阳能电池发展现状及展望

文章介绍了铜铟镓硒(CIGS)薄膜太阳能电池的产业链结构和生产技术、工艺流程、生产设备、检测设备、主要原材料及其产供销等发展现状,并对其发展前景进行展望。