全文获取类型
收费全文 | 279篇 |
免费 | 5篇 |
专业分类
财政金融 | 45篇 |
工业经济 | 9篇 |
计划管理 | 23篇 |
经济学 | 135篇 |
综合类 | 12篇 |
运输经济 | 1篇 |
旅游经济 | 1篇 |
贸易经济 | 31篇 |
农业经济 | 9篇 |
经济概况 | 18篇 |
出版年
2023年 | 3篇 |
2022年 | 4篇 |
2021年 | 6篇 |
2020年 | 11篇 |
2019年 | 5篇 |
2018年 | 7篇 |
2017年 | 15篇 |
2016年 | 16篇 |
2015年 | 2篇 |
2014年 | 15篇 |
2013年 | 76篇 |
2012年 | 8篇 |
2011年 | 21篇 |
2010年 | 13篇 |
2009年 | 5篇 |
2008年 | 16篇 |
2007年 | 14篇 |
2006年 | 11篇 |
2005年 | 11篇 |
2004年 | 5篇 |
2003年 | 2篇 |
2002年 | 6篇 |
2001年 | 1篇 |
2000年 | 2篇 |
1999年 | 1篇 |
1998年 | 2篇 |
1996年 | 1篇 |
1994年 | 1篇 |
1993年 | 1篇 |
1991年 | 2篇 |
1981年 | 1篇 |
排序方式: 共有284条查询结果,搜索用时 15 毫秒
101.
《Journal of medical economics》2013,16(9):1129-1136
AbstractObjective:The objective of this analysis was to compare costs of paricalcitol or cinacalcet plus low dose vitamin D, and of phosphate binders, in patients in the IMPACT SHPT study; and to extrapolate those to estimate expected annual maintenance costs.Methods:IMPACT SHPT was a 28-week, randomized, open-label trial. Subjects from 12 countries received intravenous (IV) or oral paricalcitol, or oral cinacalcet plus fixed IV doxercalciferol or oral alfacalcidol. The primary end-point was the proportion of subjects who achieved a mean intact parathyroid hormone (iPTH) value of 150–300?pg/mL during weeks 21–28 (evaluation period). This study compares the costs of study drugs and phosphate binders among participants during the study and annualized. This analysis includes only those subjects that reached the evaluation period (134 in each group).Results:The mean total drug costs over the study period were €2606 (SD?=?€2000) in the paricalcitol group and €3034 (SD?=?€3006) in the cinacalcet group (difference €428, p?=?0.1712). The estimated annualized costs were €5387 (SD?=?€4139) in the paricalcitol group and €6870 (SD?=?€6256) in the cinacalcet group (difference €1492, p?=?0.0395). In addition, a significantly greater proportion (p?=?0.010) of subjects in the paricalcitol arm (56.0%) achieved an iPTH of 150–300?pg/mL during the evaluation period compared to the cinacalcet arm (38.2%).Limitations:This was a secondary analysis of the IMPACT SHPT study which was not designed or powered for costs as an outcome. The dosing of study drugs and phosphate binders in the IMPACT study may not reflect actual practice, and patients were followed for 28 weeks, while the treatment of SHPT is long-term.Conclusion:Patients with SHPT requiring hemodialysis who were treated with a paricalcitol-based regimen for iPTH control had lower estimated annual drug costs compared to those treated with cinacalcet plus low-dose vitamin D. 相似文献
102.
《Journal of medical economics》2013,16(4):500-509
AbstractObjective:Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect multiple organ systems, including the kidneys (lupus nephritis) and the central nervous system (neuropsychiatric lupus, or NPSLE). The healthcare costs and resource utilization associated with treating lupus nephritis and NPSLE in a large US managed care plan were studied.Methods:SLE subjects ≥18 years of age and with claims-based evidence of nephritis or neuropsychiatric conditions were identified from a health plan database. An index date was set as a randomly drawn date from all qualifying claims during 2003–2008 for study subjects. Subjects were matched on the basis of demographic and clinical characteristics to unaffected controls. Costs and resource use were determined during a fixed 12-month post-index period.Results:Nine hundred and seven lupus nephritis subjects were matched to controls, and 1062 subjects with NPSLE were matched to controls. Mean overall post-index healthcare costs were significantly higher among subjects with lupus nephritis in comparison to matched controls ($33,472 vs $5347, p?<?0.001). Similarly, mean overall post-index healthcare costs were significantly higher among subjects with NPSLE compared to controls ($30,341 vs $4646, p?<?0.001). Subjects with lupus nephritis or NPSLE had higher mean post-index numbers of ambulatory visits, specialist visits, emergency department visits and inpatient hospital stays, compared to controls (all p?<?0.001).Limitations:Additional research, such as medical chart review, could provide validation for the claims-based identification of lupus nephritis and NPSLE subjects. Also, indirect costs were not evaluated in this study.Conclusion:Subjects with lupus nephritis or NPSLE have high costs and resource use, compared to unaffected controls. 相似文献
103.
104.
《Journal of medical economics》2013,16(3):358-363
AbstractObjective:A recent expert study (RAND Appropriateness Method (RAM)) including a panel of 12 European urologists reported that the PCA3 score may be instrumental in taking appropriate prostate biopsy (PBx) decisions, mainly for repeat PBx. This study determined the cost/benefit balance of introducing PCA3 in the decision-making for PBx in France.Methods:Two RAM models, without and with PCA3, were retrospectively applied to a sample of 808 French men who had PBx in 2010 (78% first, 22% repeat). Outcome measures included the proportion of PBx that could have been avoided (i.e., judged inappropriate) in the French sample according to both RAM models, and the estimated impact of application of these models on the annual number of PBx and associated costs for France (based on most recent published data).Results:Complete profiles were available for 698 men. In the model without PCA3, 2% of PBx were deemed inappropriate. Knowledge of PCA3 would have avoided another 7% of PBx. Repeat PBx would have been avoided in 5% of cases without PCA3 and in 37% with PCA3. For France, application of the RAM model including PCA3 would result in 18,345 fewer repeat PBx. It would be budget-neutral in the unlikely hypothesis of no complications or no costs incurred by complications and would save €1.7 million for a mean cost for complications of €100/procedure or €5 million for a mean cost for complications of €280/procedure, calculated based on US and Canadian data.Limitations:Limitations of the study are the theoretical nature of the analysis and the fact that PCA3 distributions had to be derived from other sources.Conclusions:Adoption of RAM expert recommendations including PCA3 for repeat PBx decisions in clinical practice in France would reduce the number of repeat PBx and control costs. 相似文献
105.
Geno J. Merli Judd E. Hollander Patrick Lefebvre François Laliberté Monika K. Raut 《Journal of medical economics》2016,19(1):84-90
Background:For many years, the standard of care for patients diagnosed with deep vein thrombosis (DVT) has been low-molecular-weight heparin (LMWH) bridging to an oral Vitamin-K antagonist (VKA). The availability of new non-VKA oral anticoagulants (NOAC) agents as monotherapy may reduce the likelihood of hospitalization for DVT patients.Objective:To compare hospital visit costs of DVT patients treated with rivaroxaban and LMWH/warfarin.Methods:A retrospective claim analysis was conducted using the MarketScan Hospital Drug Database for care provided between January 2011 and December 2013. Adult patients using rivaroxaban or LMWH/warfarin with a primary diagnosis of DVT during the first day of a hospital visit were identified (i.e., index hospital visit). Based on propensity-score methods, historical LMWH/warfarin patients (i.e., patients who received LMWH/warfarin before the approval of rivaroxaban) were matched 4:1 to rivaroxaban patients. The hospital-visit cost difference between these groups was evaluated for the index hospital visit, as well as for total hospital-visit costs (i.e., including index and subsequent hospital visit costs).Results:All rivaroxaban users (n?=?134) in the database were well-matched with four LMWH/warfarin users (n?=?536). The mean hospital-visit costs were $5257 for the rivaroxaban cohort and $6764 in the matched-cohort of patients using LMWH/warfarin. The $1508 cost difference was statistically significant between cohorts (95% CI?=?[?$2296; ?$580]; p-value?=?0.002). Total hospital-visit costs were lower for rivaroxaban compared to LMWH/warfarin users within 1, 2, 3, and 6 months after index visit (significantly lower within 1 and 3 months, p-values <0.05)Limitations:Limitations were inherent to administrative-claims data, completeness of baseline characteristics, adjustments restricted to observational factors, and lastly the sample size of the rivaroxaban cohort.Conclusion:The availability of rivaroxaban significantly reduced the costs of hospital visits in patients with DVT treated with rivaroxaban compared to LMWH/warfarin. 相似文献
106.
西三角经济圈的合理性分析——基于空间经济学基本原理 总被引:1,自引:0,他引:1
通过运用Walter Christaller提出的中心—地方理论,以及空间经济学的基本原理,建立了一个以重庆、成都、西安三地区为支撑点的空间区域经济模型。通过模型分析西三角经济圈的合理性,并为西三角经济的进一步健康发展提出有利建议。 相似文献
107.
本文以中国《最低工资规定》的出台作为准自然实验,基于2000-2013年企业层面微观数据,采用双重差分法系统研究了劳动力成本上升对企业加工贸易规模及转型升级的影响。本文发现,劳动力成本上升虽然缩小了企业加工贸易规模,但通过倒逼机制促进了加工贸易企业转型升级。进一步的机制检验表明,劳动力成本上升促进了加工贸易企业增加固定资产投资、扩大研发创新和在职培训的投入力度、提高生产效率,进而推动了企业加工贸易升级。最后,本文还在城市层面研究了劳动力成本、资源配置与加工贸易升级的关系,结果表明,出口市场份额再配置是劳动力成本上升促进城市加工贸易升级的重要途径:一方面,劳动力成本上升促进了出口市场份额向竞争力较强的存续加工企业再配置,另一方面,劳动力成本上升加速了低竞争力加工企业退出。本文一方面丰富了评估最低工资经济效应的研究,另一方面有助于理解中国加工贸易转型升级背后的驱动因素。 相似文献
108.
We study a two-period model of policy-making where (i) changes of current policies impose costs on all individuals that increase linearly with the magnitude of the policy shift and (ii) political power changes over time. We show that policy polarization is minimal for intermediate marginal costs. In turn, welfare is a single-peaked function of the marginal cost. One interpretation is that societies with political institutions that impose positive but moderate costs on political reforms simultaneously achieve the highest welfare and the lowest policy polarization. 相似文献
109.
110.
There is scant research on the impact of unionization on hospitality employees’ job security, health, and working conditions. This research explores employees’ beliefs of costs and benefits of unionization in hospitality organizations given that previous research has mainly focused on its influence on the firm and the industry. The findings of this study suggest that unionization can present a unique set of challenges both for line-level employees and managers. The ‘it’s not my job’ attitude associated with unionization can have a dampening impact on employees’ future career opportunities. Future research needs to consider the long-term consequences of unionization on employees. 相似文献