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41.
以张爱玲所处的特殊环境为视点,分析了她对都市通俗小说所作的贡献,并从品质上推动了都市通俗小说的发展,肯定了她在现代文学中的独特地位。  相似文献   
42.
方英文在长篇小说《落红》中所塑造的唐子羽,是一位当代多余人;方英文塑造唐子羽的文学观念和方法,是对十九世纪俄国批判现实主义创作方法的继承和延续;再将唐子羽与加缪笔下的当代多余人作以比较,便能清楚看出唐子羽这个人物的意义来。  相似文献   
43.
文章从新资源食品的定义(包括影响到食品的新技术)和新资源食品法规的范围、对来自第三方国家的传统食品的要求、新资源食品的审批和授权,以及激励创新4个方面对提案进行了剖析,并对我国食品出口企业如何规避这一新的技术性贸易壁垒提出对策建议。  相似文献   
44.
Background and objective Venous thromboembolism (VTE) is associated with long-term clinical and economic burden. Clinical guidelines generally recommend at least 3 months of anticoagulation, but, in clinical practice, concerns over bleeding risk often limit extended treatment. Apixaban was studied for extended VTE treatment in the AMPLIFY-EXT trial, demonstrating superiority to placebo in VTE reduction without increasing risk of major bleeding. This study assessed the long-term clinical and economic benefits of extending treatment with apixaban when clinical equipoise exists compared to standard of care with enoxaparin/warfarin and other novel oral anti-coagulants (NOACs) for the treatment and prevention of recurrent VTE in Canada.

Methods A Markov model was developed to follow patients with VTE over their lifetimes. Efficacy and safety for apixaban and enoxaparin/warfarin were based on AMPLIFY and AMPLIFY-EXT, while relative efficacy to other NOACs was synthesized by network meta-analysis (NMA). Dosages for NOACs and enoxaparin/warfarin were based on their respective trials and were given up to 18 months and up to 6 months, followed by no treatment, respectively. Patient quality adjusted life years (QALYs) were based on published studies, and costs for resource utilization were from a Ministry of Health perspective, expressed as 2014 CAD ($).

Results Extended treatment with apixaban compared to enoxaparin/warfarin resulted in fewer recurrent VTEs, VTE-related deaths, and bleeding events, but at slightly increased cost. The incremental cost-effectiveness ratio was $4828 per QALY gained. Compared to other NOACs, apixaban had the fewest bleeding events, similar recurrent VTE events, and the lowest overall cost, which was driven by the strong bleeding profile. In scenario analyses of acute and lifetime treatments, apixaban was cost-effective against all strategies.

Conclusions Extended treatment with apixaban can offer substantial clinical benefits and is a cost-effective alternative to enoxaparin/warfarin and other NOACs.  相似文献   
45.
Although they are key stakeholders, advertisers’ views on the usage of novel (integrated and/or interactive) advertising toward minors has remained largely unexplored in academic research. This study aims to fill this gap by examining advertising professionals’ opinions about the ethical appropriateness of using novel advertising formats aimed at children and teenagers, how to advance advertising literacy in minors, and their views of practices that are potentially privacy-invading, by means of both a quantitative online survey and qualitative in-depth interviews with Belgian advertising professionals. Results show that advertisers perceive that from 12 years onward, minors are capable to understand novel advertising formats and it is ethically justified to use them. Remarkably, advertisers would inform minors already from the age of 10 years onward about the commercial intention behind new advertising formats. Advertisers have strict opinions about collecting information online from minors. They advocate a combination of laws and self-regulation and governmental and educational campaigns to raise awareness and develop advertising literacy.  相似文献   
46.
严歌苓在充满动荡的北美社会里对普遍的人性和人类生存状态进行透视与思考。《风筝歌》和《乖乖贝比(A)》两篇小说分别以少女和幼女为主人公,从女性经验出发,以一种理性的升华来表现对人性的宽宥。严歌苓提供给我们的东西,既有性别的,更有超性别的,归根到底是在揭示人性,而且揭示的相当深刻、感人。严歌苓的才华使她的作品完全可以凭借文学性打动读者。  相似文献   
47.
《Business History》2012,54(3):327-347
Little business history has been written on the popular music industry while sociological study has tended to focus on the effect of the industry on society. This paper concentrates on how recorded popular music reached the customer, charting the evolution of the industry in the UK from a cartel structure distributing only to specialists, into an industry which allowed upstream entry freely but increasingly emphasised large-scale distribution through mass retailers by the mid-1970s. The paper examines the structure of music distribution in the UK prior to 1965 and how the industry adapted its distribution strategy to the changing environment after 1965.  相似文献   
48.
49.
王敬羲的小说不同于香港文坛五、六十年代的难民小说和通俗小说,它通过对平常生活中普通人,尤其是小职员、小市民的心理描写.传达普通人对城市生活的体验和感悟.为香港纯文学的发展吹来一股新风。  相似文献   
50.
王九生 《价值工程》2010,29(33):194-194
大众健美操是一门综合性强的艺术项目,通过对大众健美操的特点和功能分析,提出了科学、有效、安全的设计。并且运用多种教学方法来提高教学效果进行研究。  相似文献   
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