Emerging search regimes: measuring co-evolutions among research,science, and society

Scientometric data is used to investigate empirically the emergence of search regimes in biotechnology, genomics and nanotechnology. Complex regimes can emerge when three independent sources of variance interact. In our model, researchers can be considered as the nodes that carry the science system. Research is geographically situated with site-specific skills, tacit knowledge and infrastructures. Second, the emergent science level refers to the formal communication of codified knowledge published in journals. Third, the socio-economic dynamics indicate the ways in which knowledge production relates to society. Although biotechnology, genomics and nanotechnology can all be characterised by rapid growth and divergent dynamics, the regimes differ in terms of self-organisation among these three sources of variance. The scope of opportunities for researchers to contribute within the constraints of the existing body of knowledge are different in each field. Furthermore, the relevance of the context of application contributes to the knowledge dynamics to various degrees.     

Exploring the role of human resources in technology out-licensing:an empirical analysis of biotech newtechnology-based firms

Out-licensing is a technology exploitation option to generate revenues without investing in downstream complementary assets. Despite its increasing strategic relevance, the strong complexity of out-licensing activity determines a substantial discrepancy in firms’ ability to extract monetary benefits from this practice. Searching for determinants of out-licensing performance, the paper focuses in particular on the role of licensing managers. Based on a multiple case study analysis involving 26 out-licensing deals executed in seven Italian biotech NTBFs, the study shows that expert scientific skills, extensive licensing practice and prior employment in multinationals, but not an intense social network, characterise successful licensing managers, while high delegation and powerful intrinsic rewards enable individual capacities of licensing managers to translate into actual economic value.     

Decision-making in investment in overseas R&D

According to the literature, multinational firms are motivated to locate R&D activity overseas for mainly three reasons, namely: to adapt to local markets; access lower cost R&D capacity; or access unique research capability. Ireland at the beginning of the century appeared, from this finding, badly placed to attract R&D in foreign direct investment (FDI), as it had by global comparisons neither a large domestic market, a low cost economy nor a strong R&D profile. In spite of this, Ireland has succeeded in attracting significant investment in R&D projects. The cases of investment in Ireland analysed here reveal that the nature of the decision-making process itself has been a decisive factor in the outcome, and that less quantifiable factors such as cultural closeness, history, and personal relationships have played a stronger role in the outcome than would be expected from the literature.     

Battle royal in biotechnology: R&D vs. product vs. process innovations

Companies regard innovation as a central element of their business. However, as not all innovation types are the same, the central question is: should their announcements bring about the same effect on performance? This article analyses potential differences in firm value derived from the innovation-type announcements ‘R&;D’, ‘product’, and ‘process’, made by intensive news-generating firms such as biotech companies. The empirical application shows a significantly positive reaction to innovation announcements, with the prospect of future innovation (‘R&;D’ investment announcements) having greater impact on firm value than ‘product’ and ‘process’ innovations. Firm experience also acts as a moderator in this innovation–performance relationship, which is particularly relevant for entrepreneurs who need to develop and send credible signals indicating the value of the firm's intangible assets to the market.     

Pursuing a biotechnology system of innovation in Lithuania: a conceptual framework for effective policy intervention

The focus of this paper is on Lithuania, whose government released an ambitious innovation strategy to become an innovative services hub for Northern Europe by 2015, and an innovation hub by 2020. Biotechnology has been identified as a strategic sector, and whether Lithuania will be able to achieve its ambition of a fully functioning biotechnology sectoral system of innovation will be explored. With the Lithuanian government declaring that they will intervene to achieve their innovation goals, this paper argues that sound policy intervention is possible and can be done in a way that avoids the limitations of past systemic approaches. The policy approach presented is based on a modified extended industry life cycle, and the movement of system structures through three phases – background, pre-emergence and emergence – and explains how each phase lays the groundwork for transition to the next phase.     

Comment on sustainability and innovation in staple crop production in the US Midwest

This comment highlight issues when comparing genetically modified (GM) crops to non-GM ones across countries. Ignoring structural differences between agricultural sectors and assuming common yield trajectories before the time of introduction of GM crops results on misestimating the effect of GM varieties. Further data collection and analyses should guide policy-makers to encourage diverse approaches to agriculture, rather than excluding specific technologies (like GM crops) from the onset.     

生物工程技术在船舶防污染中的应用

随着航运业的蓬勃发展,船舶对海洋环境造成的污染也越来越严重,传统的物理方法和化学方法在处理船舶所造成的这些污染过程中已经难以满足治理需要,而生物工程技术凭借着效率高、安全、廉价、无毒的优良特性正逐渐应用在船舶污染防治中,为此本文着重论述了现代生物技术在船舶防污染和保护海洋生态环境中的应用。     

Old technology meets new technology: complementarities,similarities, and alliance formation

Alliance formation is commonplace in many high‐technology industries experiencing radical technological change, where established firms use alliances with new entrants to adapt to technological change, while new entrants benefit from the ability of established players to commercialize the new technology. Despite the prevalence of these alliances, we know little about how these firms choose to ally with specific firms given the range of possible partners they may choose from. This study explores factors that lead to alliance formation between pharmaceutical and biotechnology companies. We focus on the alliance tie as the unit of analysis and argue that dyadic complementarities and similarities directly influence alliance formation. We then introduce a contingency model in which the positive effect of complementarities and similarities on alliance formation is moderated by the age of the new technology firm. We draw theoretical attention to the intersection between levels of analysis, in particular, the intersection between dyadic and firm‐level constructs. We find that a pharmaceutical and a biotechnology firm are more likely to enter an alliance based on complementarities when the biotechnology firm is younger. Another noteworthy finding is that proxies for broad capabilities appear to be at least as effective, if not more so, in predicting alliance formation compared to fine‐grained science and technology‐related indicators, like patent cross‐citations or patent common citations. We conclude by suggesting that future studies on alliance formation need to take into account interactions across levels; for example, how dyadic capabilities interact with firm‐level factors, and the advantages and disadvantages of more or less fine‐grained measures of organizational capabilities. Copyright © 2007 John Wiley & Sons, Ltd.     

What is sustainable agriculture? Empirical evidence of diverging views in Switzerland and New Zealand

Public debates on sustainable agriculture tend to be shaped by dominant political stakeholders with a particular political agenda. They simultaneously contribute and respond to the formation of public opinion. In this paper, we investigate to what extent stakeholder attitudes and interests help explain national conceptions of sustainable agriculture and how these conceptions diverge between countries with different agricultural policies.For that purpose, we conducted two stakeholder perception surveys in Switzerland and New Zealand. The data analysis revealed that there are significant differences in perception between the two countries. While Swiss respondents felt that Swiss agriculture is already quite sustainable and that international trade and new technologies are likely to render it less sustainable, New Zealand respondents generally thought that economic and technological change is necessary to make agriculture more sustainable. The conservative Swiss attitude is in accordance with the country's defensive agricultural policy while the more progressive New Zealand attitude is clearly linked to its need to reconcile agricultural sustainability with national competitiveness.     

技术专家办企业的农业生物技术推广模式探讨

技术推广模式是关系到科技成果转化和相关产业稳定发展的重要因素.在对我国原有四种农业技术推广模式分析的基础上,构建和完善了技术专家领衔办企业的农业生物技术推广模式及运行机制,并对这种模式的未来发展定位问题进行了探讨.