Simulation driven inferences for multiply imputed longitudinal datasets*

In this article, we demonstrate by simulations that rich imputation models for incomplete longitudinal datasets produce more calibrated estimates in terms of reduced bias and higher coverage rates without duly deflating the efficiency. We argue that the use of supplementary variables that are thought to be potential causes or correlates of missingness or outcomes in the imputation process may lead to better inferential results in comparison to simpler imputation models. The liberal use of these variables is recommended as opposed to the conservative strategy.     

我国建筑业全生命周期价值链的应用研究

长期以来,我国建筑业缺乏对全生命周期价值链管理的整体关注,价值链中各个环节相互脱节,没有共同的价值目标,导致了成本较高的现状。本文旨在通过对建筑业全生命周期价值链的分析,拓展我国建筑业成本管理的关注面。并通过工程总承包模式对现有价值链进行优化,把勘察、设计、施工归集在同一个主体下管理,提高用户对建筑产品的满意度,降低产品成本。     

An efficient budget allocation policy for decentralisation of responsibility for site decontamination projects

Selection and execution of site decontamination projects is often best left to local authorities, in accordance with the subsidiarity principle, even though the budget for such projects is made available through a central authority. In this paper we suggest a practical budget allocation policy which a central authority can employ to allocate budgets to local authorities, while still optimising the central authority's environmental objective function. The procedure is fully consistent with the principle of decentralisation of responsibility for selection and execution of projects, and requires a minimum information exchange between local and central levels. Despite the information asymmetry between local and central levels, incentive compatibility problems can be (partially) prevented by choosing an appropriate evaluation mechanism. At the same time, the procedure is computationally effective and efficient, and can guarantee a fair budget allocation, making it easy to implement and politically acceptable.     

产品内贸易、技术创新与中国企业可持续发展

在科技革命和经济全球化的共同作用下，特别是随着FDI的增长和跨国公司的全球布点，传统意义上的以商品贸易为基础的国际分工正在被打破，国际分工逐步深入到企业内部，分工方式由产业间分工向产业内部产品分工和要素分工延伸。本文以当前新贸易现象为实践基础，以贸易分工理论为理论基础，初步构建产品内贸易的理论模型及其利益分配机制，从产品内分工视角分析产品内贸易模式对发展中国家贸易条件的影响，并认为中国企业应该在国际分工价值链上进行攀升，进行技术创新，提升在国际贸易中的地位，化比较优势为竞争优势，实现企业的可持续发展。     

Cost Uncertainty and Unilateral Abatement

Unilateral abatement is sometimes advocated in order to set a good example that will make other countries follow. The aim of this paper is to investigate whether existence of correlated cost uncertainty provides an incentive for a country to undertake unilateral abatement. The theoretical model is driven by two main mechanisms; first, a learning effect, as the follower country might reduce its risk premium as it can observe the cost level in the leader country. Second, there is the public good effect, i.e., the marginal benefit of abatement declines when abatement is a public good and other countries contribute to pollution reductions. Results shows that unilateral abatement would be efficient in reducing uncertainty about the unit costs of abatement if a country with low cost uncertainty would undertake abatement first, while a country with initially high cost uncertainty would follow. However, countries may prefer to act simultaneously because of the larger uncertainties that are inherent in a sequential game.      

中外建筑企业项目成本控制比较研究——兼谈建筑企业项目成本控制体系和公司财务的整合

随着建筑市场的日趋成熟,建筑施工企业在建筑项目上的竞争愈加激烈,项目的利润空间越来越小.这就要求各施工企业加强自身的成本控制,降低成本,向管理要效益,争取利润的最大化.本文拟分析和比较中外建筑企业在项目成本控制方面存在的差异,以期能改进我国建筑企业的项目成本控制体系,使其更具竞争力.     

A landscape approach for assessing the biodiversity value of indigenous forest remnants: Case study of the Manawatu/Wanganui region of New Zealand

To halt the decline of biodiversity in New Zealand, the government has formulated a strategy of maintaining and restoring a full range of remaining natural habitats to a healthy functioning state. Many indigenous forest remnants exist on private land, and these could be utilised to increase biodiversity. Resources for conservation of forest remnants are limited, so they must be used wisely to deliver the greatest possible biodiversity gain. This paper presents a rapid method for valuing the biodiversity of a region's indigenous forest remnants to help prioritise conservation resources. The region is divided into environmentally distinct areas called land environments. A detailed land-cover map is derived from satellite imagery and used to estimate the proportion of natural habitats remaining in each land environment; from this the biodiversity value of any forest remnant may be calculated. The method is rapid and does not require detailed biodiversity information. When combined with conservation costs, it may be used to create a priority list of forest remnants for conservation. The Manawatu/Wanganui region of New Zealand is used as a case study to demonstrate the method.     

A cost analysis of SIR-Spheres yttrium-90 resin microspheres versus tyrosine kinase inhibitors in the treatment of unresectable hepatocellular carcinoma in France,Italy, Spain and the UK

Abstract

Background and aims: A wide range of treatment options are available for hepatocellular carcinoma (HCC), including systemic treatment with tyrosine kinase inhibitors (TKIs) such as sorafenib and lenvatinib, immunotherapies, locoregional therapies such as selective internal radiation therapy (SIRT) and treatments with curative intent such as resection, radiofrequency ablation and liver transplantation. Given the substantial economic burden associated with HCC treatment, the aim of the present analysis was to establish the cost of using SIRT with SIR-Spheres yttrium-90 (Y-90) resin microspheres versus TKIs from healthcare payer perspectives in France, Italy, Spain and the United Kingdom (UK).

Methods: A cost model was developed to capture the costs of initial systemic treatment with sorafenib (95%) or lenvatinib (5%) versus SIRT in patients with HCC in Barcelona Clinic Liver Cancer (BCLC) stages B and C. A nested Markov model was utilized to model transitions between progression-free survival (PFS), progression and death, in addition to transitions between subsequent treatment lines. Cost and resource use data were identified from published sources in each of the four countries.

Results: Relative to TKIs, SIRT with SIR-Spheres Y-90 resin microspheres were found to be cost saving in all four country settings, with the additional costs of the microspheres and the SIRT procedure being more than offset by reductions in drug and drug administration costs, and treatment of adverse events. Across the four country settings, total cost savings with SIR-Spheres Y-90 resin microspheres fell within the range 5.4–24.9% and SIRT resulted in more patients ultimately receiving treatments with curative intent (4.6 vs. 1.4% of eligible patients).

Conclusion: SIR-Spheres Y-90 resin microspheres resulted in cost savings relative to TKIs in the treatment of unresectable HCC in all four country settings, while increasing the proportion of patients who become eligible for treatments with curative intent.     

基于研发成本考虑的市场结构优化解析

研发直接带来厂商成本的变化，进而由于技术复杂度的不断提高及研发带来的规模经济，会导致多数产业市场集中度逐渐提高。在专利保护与许可证制度下，当研发导致的沉没成本比较小时，会因其研发速度更快而使厂商数量较多的竞争性市场的福利好于寡占或垄断市场。合作创新与国内竞争可以优化市场结构，提升我国企业研发能力，应对经济全球化的挑战。     

上市公司经理层激励机制模式改进研究

文章基于马斯洛的需要层次理论，提出上市公司经理层激励机制的组成并分析了它们的相互关系，概括了我国上市公司经理层激励机制的现有模式并提出改进建议，指出了在充分发达的经理市场环境下经理层激励机制的理想选择应该具备的模式。