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1.
Background: There is a critical need to focus limited resources on sub-groups of patients with obesity where we expect the largest return on investment. This paper identifies patient sub-groups where an investment may result in larger positive economic and health outcomes.

Methods: The baseline population with obesity was derived from a public survey database and divided into sub-populations defined by demographics and disease status. In 2016, a validated model was used to simulate the incidence of diabetes, absenteeism, and direct medical cost in five care settings. Research findings were derived from the difference in population outcomes with and without weight loss over 15 years. Modeled weight loss scenarios included initial 5% or 12% reduction in body mass index followed by a gradual weight regain. Additional simulations were conducted to show alternative outcomes from different time courses and maintenance scenarios.

Results: Univariate analyses showed that age 45–64, pre-diabetes, female, or obesity class III are independently predictive of larger savings. After considering the correlation between these factors, multivariate analyses projected young females with obesity class I as the optimal sub-group to control obesity-related medical expenditures. In contrast, the population aged 20–35 with obesity class III will yield the best health outcomes. Also, the sub-group aged 45–54 with obesity class I will produce the biggest productivity improvement. Each additional year of weight loss maintained showed increased financial benefits.

Conclusions: This paper studied the heterogeneity between many sub-populations affected by obesity and recommended different priorities for decision-makers in economic, productivity, and health realms.  相似文献   
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The Sustainable Tourism Attitude Scale (SUS-TAS) has been used as a tool to gauge the sentiment of local residents toward sustainable tourism development. This scale has been validated in cross-cultural settings by several scholars. In a like manner, in order to validate this scale, data were collected in the Cape Verde islands (off the coast of Africa) and the results showed (1) a parsimonious version of the 21-item SUS-TAS that facilitates the process of data collection without compromising its robustness and psychometric properties, (2) a validated second-order factor model, confirming that the seven factors of SUS-TAS can be loaded in two broader dimensions named “perceived tourism impacts” and “expected tourism sustainability”, (3) a SUS-TAS second-order factor model with validity in predicting residents’ support for sustainable tourism development, (4) that SUS-TAS can be interpreted by seven individual factors and/or as a global factor as indicated by the hierarchical measurement model and predictive validity. Methodological and theoretical interpretations are discussed and future refinement and applications are also offered.  相似文献   
3.
We consider communication of quality via cheap talk and dissipative advertising expenditures, when consumers have heterogeneous tastes for quality, and price information must be acquired through costly search. For search pods, cheap talk communicates quality when fixed costs are roughly constant across quality levels, while if fixed costs vary greatly with quality, then firms having the higher fixed-cost quality level use dissipative advertising. For experience goods, quality can be communicated by cheap talk in a range where low-quality firms have greater fixed costs, and low-quality firms use dissipative advertising if their fixed costs are greater still.  相似文献   
4.
This paper offers a new theory of limit pricing. Incumbents from different markets or regions "compete" against one another, with each attempting to price in a manner that deflects entry into the others' markets. An entrant is imperfectly informed as to the incumbents' respective investments in cost reduction and seeks to enter markets in which incumbents have high costs. In a focal equilibrium, the entrant uses a simple "comparison strategy," in which it enters only the highest-priced markets, and incumbents engage in limit-pricing behavior. The influence on pricing of the number of markets and the scope of entry is also reported. Throughout, the central feature of the analysis is that an incumbent's price affects its investment incentives, with lower prices being complementary to greater investment.  相似文献   
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The role offamily social support in the relationship between stressful life events and distress and well-beingfor high school seniors was explored. Ensel and Lin's independent, deterioration, and counteractive models were examined through the use of structural equation modeling. Both stress-deterring and stress-coping models were supported. The implicationsfor understanding the relationships proposed in these models enables adolescents and their families to use their resources of support to their greatest potential.  相似文献   
6.
This study tests five potential drivers underlying the acceptance of SMS advertising. After developing a scale to measure behavioral responses to SMS advertising, the relationships between the acceptance of SMS advertising, intention to receive SMS advertising and behavioral responses to SMS advertising are tested. A convenience sampling method was employed. Survey questionnaires were distributed across Western Australia. The return yielded 203 usable questionnaires from the respondents. Several factors emerge as significant drivers of acceptance of SMS advertising including utility of SMS advertisements, context of SMS advertisements and attitudes to advertising in general. Contrary to expectation, control over SMS advertisements did not emerge as a significant driver for acceptance of SMS advertising. Trust in advertisers and laws did not emerge as a significant driver of the acceptance of SMS advertising among Australian respondents. Advertisers who pursue consumer acceptance should strive to build utility and context considerations into their SMS campaigns. Future research opportunities include testing the drivers of SMS advertising to further investigate the impact of control and trust on acceptance of SMS advertising in other countries where the SMS advertising has not been explored yet.  相似文献   
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Journal of Business Ethics - Prior research has demonstrated a strong relationship between team performance and team members’ team efficacy beliefs and perceptions of social integration....  相似文献   
9.
Making as a design-centered learning activity has recently received significant attention in education. We use literacies—how individuals use representations to learn—to explore the STEM literacy practices of experienced designers and makers. Describing makers’ representational practices in STEM contexts can inform the design of literacy supports for young makers that can encourage their use of representations to connect STEM disciplines and design practices. We interviewed experienced makers to describe one literacy practice central to design: identifying, organizing, and integrating information. Makers enacted this practice within specific making processes—e.g., designing—with the purpose of sourcing and navigating information related to their chosen problems. The research supports efforts to bridge learning while making with learning in schools by positioning STEM literacies as central practices involved in the processes of designing and making.  相似文献   
10.
    
The purpose of this paper is to contrasts four different multivariate methods; multiple regression using principal components, factors analysis, discriminant analysis involving another use of principal components, and canonical correlation. The method adopted to compare and constrast the techniques is to make careful note of the assumptions involved in each model and to apply each form of analysis to variables drawn from the same set of data.  相似文献   
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