The economic burden of depression among adults with rheumatoid arthritis in the United States

Aims: Depression is the most frequent comorbidity reported among patients with rheumatoid arthritis (RA). Comorbid depression negatively impacts RA patients’ health-related quality-of-life, physical function, mental function, mortality, and experience of pain and symptom severity. The objective of this study was to assess healthcare utilization, expenditures, and work productivity among patients with RA with or without depression.

Materials and methods: Data from adult patients who had at least two visits each related to RA and depression over a 1-year period were extracted from the Truven Health MarketScan research databases. Outcomes comprised healthcare resource utilization, work productivity loss, and direct healthcare costs comparing patients with RA with depression (n?=?3,478) vs patients with RA without depression (n?=?43,222).

Results: Patients with RA and depression had a significantly greater relative risk of hospitalization and number of all-cause and RA-related hospitalizations, utilization of emergency services, days spent in the hospital, physician visits, and RA-related surgeries compared with RA patients without depression. Patients with RA and depression had a higher risk of and experienced more events and days of short-term disability compared with patients without depression. The incremental adjusted annual all-cause and RA-related direct costs were $8,488 (95% CI = $6,793–$10,223) and $578 (95% CI = –$98–$1,243), respectively, when comparing patients with RA and depression vs RA only.

Limitations: The current analysis is subject to the known limitations of retrospective studies based on administrative claims data.

Conclusions: This study suggested increased healthcare utilization, work productivity loss, and economic burden among RA patients due to comorbid depression. These findings emphasize the importance of managing depression and including depression as a factor when devising treatment algorithms for patients with RA.     

军民融合协同创新驱动产业园区高质量发展研究

军民融合产业园区高质量发展对于推进军民深度融合、在全国形成可复制可推广经验具有重要意义。军民融合协同创新通过促进新知识涌现、推进新产业集聚发展，最终汇聚经济发展新动能，驱动园区高质量发展。在提出军民融合协同创新驱动园区高质量发展的机理与组织框架基础上，将发展模式归纳为以分享经济为背景的资源共享模式、以新型研发机构为核心的第三方模式、以产业联盟为核心的产业链拓展模式和以交易平台为核心的“PPP”模式，最后提出相关对策建议。     

国有风险资本与企业融资约束: 如愿以偿还是事与愿违?

我国国有风险资本是否实现了设立之初的目标,即是否纾解了企业融资困难呢?文章基于上市企业微观数据和手动采集的国有风险资本数据对此进行了系统研究.实证结果稳健地显示,国有风险资本可有效缓解企业后续融资约束,我国政府参与风险投资活动是有效的.进一步地,高持股比例、多联合投资、高政治层级的国有风险资本对受资助企业融资约束的缓解作用更强;且国有风险资本对经济欠发达、低制度质量环境下的企业、面临高环境不确定性和高竞争程度企业、民营企业、成长期与动荡期企业能产生更大的影响.机制检验表明,国有风险资本既能通过认证作用显著降低企业信息不对称程度,又能发挥政治关联的资源效应,包括显著促进银企关系和企业的商业信贷获取能力,并提升企业获得政府补贴的水平,从而减轻企业资金负担,缓解其融资约束.经济后果分析表明,国有风险资本能显著降低企业外部融资的股权资金成本和债务资金成本,帮助改善企业融资贵的难题,而且国有风险资本有助于企业在创新和经营方面的良性发展.但国有风险资本并未起到有效监督作用,不能缓解企业代理问题,尤其是会导致第一类代理成本的明显提高,而高管薪酬提升是其中的重要原因.据此,文章认为在未来的国有风险资本发展中,要把握"政府角色"介入的尺度,完善国有风险资本对企业的监督管理机制.同时适当兼顾各地区发展不平衡的情况,对中西部地区的国有风险资本发展提供适当且必要的帮助,以促进国有风险资本在新时期的长足发展.     

管理层权力制衡强度、债务约束与企业创新投资

企业创新是国家经济可持续增长的关键，受到管理层意愿的影响，因而需要对内部经营者的权力进行制衡。以2010-2018年我国A股上市公司为研究样本，实证检验管理层权力制衡强度对企业创新投资的影响，以及不同债务约束情境下高商业信用配置、高负债水平的调节效应，此外，还考察了产权性质的差异化影响。研究表明，管理层权力制衡强度越大，企业创新投资水平越高；高商业信用强化了该促进作用，而高负债水平弱化了该促进作用。进一步研究发现，管理层权力制衡强度与企业创新投资的关系在民企中更显著；国企能够更好地获得和运用商业信用，使其高商业信用对该关系的强化效应更显著；民企具有更强的债务约束，其高负债水平对该关系的弱化效应更明显。     

利用价值工程在棚户区项目拆迁地块选址决策的模型建立

本文以价值工程理论为基础,收集现有不同地块基础数据,利用多元线性回归方法确定备选方案棚户区改造项目的成本系数.通过分析影响拆迁地块选址决策影响因素,利用层次分析法确定各备选方案功能系数.对各备选方案的价值系数进行计算后,以价值系数为评价值确定最优拆迁地块.     

The Role of Ethical Standards in the Relationship Between Religious Social Norms and M&A Announcement Returns

Journal of Business Ethics - Prior studies suggest that firms headquartered in areas with strong religious social norms have higher ethical standards. In this study, we examine whether the ethical...     

经济带:新发展阶段的新愿景

经济带已成为承东启西、连南贯北的"经济主骨架",在国民经济整体格局中的战略地位日益凸显,对我国经济发展具有重大战略意义.经济带的形成有其深刻的理论基础和现实条件,我国"两横"——长江经济带和陇海兰新经济带,以及"三纵"——沿海经济带、京广京哈经济带、包昆经济带五条经济带,需要进一步集聚经济要素,破除要素流动壁垒,提升节点城市能级,推动区域经济合作,以经济带建设推动我国经济高质量发展.     

Who benefits from partial tax coordination?

In this paper, we investigate whether partial tax coordination is beneficial to countries within and outside a tax union, in which countries are supposed to compete in taxes and infrastructure. Our results demonstrate that a subgroup of countries agreeing on a common tax rate can harm both member and nonmember states. This is in contrast to the classical findings that partial tax harmonisation is Pareto improving. When a minimum tax rate is imposed within a tax union, we demonstrate that it does not necessarily improve the welfare of the member countries. Moreover, both the high‐tax and low‐tax countries can be worse off. This conclusion is at odds with the classical result that a high‐tax country benefits from the imposition of a lower tax bound.     

金融科技对传统银行行为的影响——基于互联网理财的视角

本文使用2011-2015年263家银行的年报数据和北京大学数字金融研究中心基于蚂蚁金服用户数据构建的地市级数字金融普惠指数,探究金融科技的发展对银行行为的影响。研究发现金融科技的发展实质上推动了一种变相的利率市场化,改变了银行的负债端结构,使得银行负债端越来越依赖于同业拆借等批发性资金。负债端结构的改变导致银行资产端风险承担偏好上升,但是借贷利率和净息差都有所下降。即银行选择了更高风险的资产来弥补负债端成本上升所造成的损失,但并没有将成本向下游企业转移。此外,本文还发现规模越大的银行受到金融科技的冲击越小。