External technology acquisition in large multi-technology corporations

Based on different contractual forms and their associated degrees of organizational integration, a typology of strategies for technology acquisition (sourcing) is constructed. Based on a sample of corporations in Europe, Japan and US, it is shown that external acquisition of technology through various strategies increases in importance in general. Product case studies further show that external acquisition of technology is associated with technology diversification into increasingly costly new technologies. As a result corporations become multi-technological ('multech'). At the same time quasi-integrated corporate systems of innovation arise in which in-house R&D is managed together with a mix of strategies for external acquisition of technology, using various contractual forms. This presents new challenges to traditional in-house R&D management. Technology diversification is moreover shown to be associated with growth of sales as well as with growth of R&D expenditures. A high level of external technology acquisition presents risks that ought to lead companies to consider technology based product diversification.     

Aspects of the integration of technical functions for efficient product development

It is probably safe to say that today it is universally accepted and often common knowledge that cooperation between product development and the market functions is crucial for the ability of companies to develop market oriented products. Likewise, there are some strong indications that well functioning cooperation between production and product development is crucial for the development of products that are efficient to manufacture. However, no satisfactory solutions have yet been found to the issues of integration and cooperation. Although there is a consensus of opinion among companies that the need for cooperation is very great, a number of issues still remain to be solved. It is, for example, not clear on which issues cooperation should take place, nor which functions should be involved, nor yet how this should be done. This paper tries to answer some of these questions.     

Institutions,Entrepreneurship, and Growth: Biomedicine and Polymers in Sweden and Ohio

This paper examines the role of institutions in explaining the differences in performance with respect to entrepreneurship and growth in two industry clusters in two countries: the biomedical/biotechnology and polymer-based industry clusters in Sweden and Ohio. Both clusters are about twice as large in Ohio as in Sweden, even though the industrial history and the composition of industrial output in general are quite similar in the two regions, and even though the Ohio economy is only about 25% larger than that of Sweden.Four types of institutional factors are examined: The science base and mechanisms of technology transfer; the density of networks and the role of business support services and companies in related industries; the entrepreneurial climate, especially the availability of finance; and the policy environment and other infrastructure.Major findings are that the science base plays a different role in the two clusters and that the regions differ in the absorption of new technology, partly due to the differences in the size and structure of firms, that bridging institutions have contributed significantly to connectivity of networks in Ohio, and that the greater availability of venture capital and entrepreneurial management skills makes the Ohio environment for entrepreneurship more supportive than that in Sweden.     

Small firms,business dynamics and differential development of economic well-being

In recent years a growing stream of research has examined the relationships between structural characteristics of regions and their levels of new firm formation. This empirical study aims at supplementing such findings with analyses that include other forms of business dynamics, and also the possible well-being effects of such dynamics. From a unique and comprehensive data set that tracks all births, deaths, expansions, and contractions of commercial business establishments in Sweden 1985–89, six groups of regions with different patterns of dynamics are extracted by means of cluster analysis. The clusters' structural characteristics and their development of economic well-being are also compared. The results suggesta) that the patterns of business dynamics are contingent on the structural characteristics of regions,b) that high formation and turnover of establishments are associated with a relative increase in economic well-being, andc) that small, autonomous firms have a vital role in this process.     

Cost effectiveness of benralizumab for severe,uncontrolled oral corticosteroid–dependent asthma in Sweden

Abstract

Aim: We investigated cost effectiveness of benralizumab vs. standard of care (SOC) plus oral corticosteroids (OCS) for patients with severe, eosinophilic OCS-dependent asthma in Sweden.

Materials and methods: A three-state, cohort-based Markov model of data from three Phase III benralizumab clinical trials (ZONDA [NCT02075255], SIROCCO [NCT01928771], and CALIMA [NCT01914757]) was used to assess the incremental cost-effectiveness ratio of benralizumab vs. SOC plus OCS. Health outcomes were estimated in terms of quality-adjusted life-years (QALYs). The model included costs and disutilities associated with extrapolated OCS-related adverse events. Patients with severe asthma were defined as those receiving OCS ≥5?mg/day.

Results: Benralizumab demonstrated a cost-effectiveness ratio vs. SOC plus OCS of 2018 Swedish Kronor (SEK) 366,855 (€34,127) per QALY gained, based on increases of 1.33 QALYs and SEK 488,742 (€45,344) per patient. Benralizumab treatment costs contributed most to incremental costs. The probability of benralizumab’s being cost-effective with willingness-to-pay (WTP) thresholds between SEK 429,972 (€40,000) and SEK 752,452 (€70,000) ranged from 75% to 99%.

Limitations: Potential limitations of these analyses include the use of combined data from three different clinical trials, a one-way sensitivity analysis that did not include mortality and transition estimates, and Observational & Pragmatic Research Institute (OPRI) data from the UK as a proxy of the Swedish health care system.

Conclusions: The results of these analyses demonstrate that benralizumab has a high probability of being cost-effective compared with SOC plus OCS for a subgroup of patients with severe, eosinophilic asthma receiving regular OCS treatment and may support clinicians, payers and patients in making treatment decisions.     

Technology Sharing in Manufacturing Business Groups

Technology represents the primordial force for companies and organizations in securing long‐term competitiveness. In the intensive search to access new technology, organizations are more and more looking beyond the borders of the focal firm and becoming involved in various networks with suppliers, consultants, partners, and others. However, the distinction between the focal firm, on the one hand, and networks, on the other, is in this paper argued to be too extensive without intermediating nuances. Less focus is given to an in‐between perspective configured by business groups or concerns here defined as parent corporations with subsidiary companies. It is this perspective of business groups with characteristics between individual firms and open networks that is of interest in this paper. The focus is on manufacturing business groups in which the companies will typically have individual as well as common technologies. The research aim is to develop a framework to be used as an analytical tool for understanding and organizing technology sharing in manufacturing business groups. The research approach was to study technology sharing in a natural setting combining multiple in‐depth sources of evidence in a clinical research setting. A prestudy identified key dimensions in classifying cases leading to four clusters of typified cases. Data were gathered from meetings with 24 managers from various research and development (R&D) units who met regularly every other week during seven months, in‐depth interviews, internal documents and protocols, and workshops. Following the clinical field‐study approach, findings are theoretically validated in relation to literature. The analysis identifies and depicts four different types of technology‐sharing scenarios in manufacturing business groups. Each type has particular characteristics of its own. The four scenarios together provide a synthesized portfolio with different types of dimensions. A first dimension makes a distinction between sharing new technology development versus existing technology. Another distinguishes between technologies aimed at the whole business group and those aimed at specific segments. The two dimensions together comprise four different types of technology‐sharing alternatives. Each one of them can be used at the focal firm, and together, they are applicable from a business group perspective comprising technology‐sharing portfolios of manufacturing business groups.     

Effects of commitment on intentional loyalty at the person-to-person and person-to-firm levels

This study explores how customers’ affective commitment and calculative commitment to the personal adviser and bank, respectively, affect their intentional loyalty to the personal adviser and bank. Data were collected using a web survey of mass affluent customers of a major Swedish bank. Responses were measured and analysed using factor, correlation, and regression analyses. The results reveal that the person-to-person and person-to-firm loyalty categories are influenced by affective and calculative commitment to the personal advisor and by affective commitment to the bank, but not by calculative commitment to the bank. Moreover, there is a strong relationship between customer loyalty to the personal adviser and to the bank. It can be concluded that affective commitment has a stronger overall impact on customer loyalty than does calculative commitment, indicating the importance of creating affective ties with customers, and that personal advisers are central to bank – customer relationships. The importance of financial issues to mass affluent customers implies that both affective commitment and calculative commitment to the personal adviser are important in building customer loyalty to a bank or brand.     

Flexible technology and industrial structure in the U.S.

This paper analyzes the development over the postwar period of output, employment, and the number of plants in manufacturing in the United States. It is shown that the distribution of flexible technology in the form of machine tools (NCMTs) shifted markedly toward small plants during the 1980s. It is found that the probability of adoption and the penetration rate of NCMTs are higher in large than in small plants, even though the number of NCMTs per worker is much higher in small plants. This apparent paradox is explained. It is also suggested that the shift of output towards smaller plants is correlated with the increased use of flexible technology, and that this reflects changes in the division of labor among plants of various sizes, as well as changes in the composition and organization of production in large plants.The authors would like to thank Bennett Harrison, an unknown referee, and the editors of this Journal for valuable comments. Any remaining errors are the responsibility of the authors.