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Preference-based measures of health-related quality-of-life including, but not limited to, the EQ-5D, HUI2 and the SF-6D have been increasingly used in calculations of quality-adjusted life years for cost effectiveness analyses. However, the uncertainty around the measures’ value sets is commonly ignored in economic evaluation. There are several types of uncertainties, including methodological, structural, and parameter uncertainties, with the latter being the focus of this review paper. The objective is to highlight the gap in the literature regarding the existence of uncertainty in the value sets, focusing mainly on the EQ-5D and SF-6D. To the best of the authors’ knowledge, this is the first systematic review revolving around uncertainty. After searching extensively for studies involving uncertainties in all preference-based measures, the results showed that uncertainty has been approached through different means, while parameter uncertainty has been ignored in most, if not all, cases. These findings suggest that uncertainty should be accounted for when using preference-based measures in economic evaluations. Ignoring this additional information could impact misleadingly on policy decisions. 相似文献
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In recent years, the prevalence of infertility has increased due to delayed childbearing and an increase in the rate of male infertility. Given the high cost of fertility treatment, this option is not valid for families with a low income, and those who can afford it usually choose to have multiple embryo transfer, which has led to an increase in multiple birth rates and an increase in the cost of perinatal care. Due to the expected increase in infertility and decrease in the national live birth rate, the US should set a plan to fund infertility treatment and lead a policy for single embryo transfer. This will offset the decrease in the national birth rates and decrease expenditure on perinatal and neonatal complications resulting from multiple births. 相似文献
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This paper examines the relationship between organizational learning culture, learning transfer climate, and organizational innovation. The objective was to test the ability of learning organization culture to account for variance in learning transfer climate and subsequent organizational innovation, and to examine the role of learning transfer climate as a mediator between learning organization culture and innovation. Results showed that organizational learning culture predicted learning transfer climate, and both these factors accounted for significant variance in organizational innovation. 相似文献
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Decision making in public companies follows an organized structure dominated by risk aversion. The decisions in private entrepreneurial firms tend to be driven by overconfidence and reliance on trial and error. Such entrepreneurial attitudes are reinforced by high levels of profitability. The authors argue that this difference in decision-making paradigms limits the wealth effect of blockholder formation by the profitable private target's owners in mergers and acquisitions. Blockholder formation by private target owners is associated with substantial acquirer shareholder gains in the acquisitions of targets with relatively low and moderate profitability levels. To the opposite, the market reacts to blockholder formation by the owners of highly profitable targets with skepticism. Such announcements are associated with insignificant wealth effects overall and substantial acquirer losses in acquisitions in human capital-intensive sectors whereby disagreements are likely to be consequential. Acquirers understand these wealth effects and reduce the extent of stock financing when acquiring highly profitable targets. 相似文献
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Consider a linear regression model and suppose that our aim is to find a confidence interval for a specified linear combination of the regression parameters. In practice, it is common to perform a Durbin–Watson pretest of the null hypothesis of zero first‐order autocorrelation of the random errors against the alternative hypothesis of positive first‐order autocorrelation. If this null hypothesis is accepted then the confidence interval centered on the ordinary least squares estimator is used; otherwise the confidence interval centered on the feasible generalized least squares estimator is used. For any given design matrix and parameter of interest, we compare the confidence interval resulting from this two‐stage procedure and the confidence interval that is always centered on the feasible generalized least squares estimator, as follows. First, we compare the coverage probability functions of these confidence intervals. Second, we compute the scaled expected length of the confidence interval resulting from the two‐stage procedure, where the scaling is with respect to the expected length of the confidence interval centered on the feasible generalized least squares estimator, with the same minimum coverage probability. These comparisons are used to choose the better confidence interval, prior to any examination of the observed response vector. 相似文献
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Samer Sarofim Elizabeth Minton Amabel Hunting Darrell E. Bartholomew Saman Zehra William Montford Frank Cabano Pallab Paul 《The Journal of consumer affairs》2020,54(3):1028-1061
Religion is an indelible force in society, yet research examining its influence on consumption, particularly in the context of financial well-being is lacking. Thus, this paper presents a conceptual framework of factors influencing, and outcomes associated with, the effects of religion on financial well-being. Specifically, this paper introduces a conceptual framework aimed at understanding how religion influences financial decisions and well-being, both from a consumer and a business perspective. Focus groups were conducted with consumers and financial practitioners to support the development of the conceptual framework. Most novel to this framework is the identification of potential process mechanisms explaining this relationship, including trust, affect, risk propensity, and perceived personal control. The framework concludes with potential interventions targeted at consumers and businesses to improve financial well-being. This propositions-based conceptual framework serves as a research agenda to guide and aid scholars, consumer advocacy groups, policymakers, and marketers in promoting greater financial well-being. 相似文献
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This paper explores the development of market roles and transactions in fuel-efficient stoves in Darfur from 1997 to 2008 as a grounded example of how subsistence markets are socially constructed in post-conflict settings. Using a combination of archival texts, interviews, and real-time discourses by protagonists, this study explains the who, what, why and how of emergent marketplaces by showing how development interventions come to imbue market participants and transactions with socially (re)constructed meanings. The fitful emergence of subsistence marketplaces for fuel-efficient in Darfur is punctuated by development interventions which at times under- or misrepresent market participants and by successes and failures in bringing together trainers, producers, sellers, consumers and users of fuel-efficient stoves. Subsidies and handouts delay and distort the emergence of grassroots demand, choices, and prices; a plurality of competing development interventions re-shape the supply. By the end of 2008, the subsistence market for fuel-efficient stoves catches momentum, engaging over 52% of the Darfuri communities in market transactions for the product. As market participants gain voice and influence they reshape the market to favour mud stoves over metal stoves. Reports by several development organizations suggest that among fuel-efficient stove users, 90% use mud models, and 49% of women who own both mud and metal stoves prefer mud stoves. 相似文献
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Highway maintenance marginal costs have been estimated in the literature using the perpetual overlay indirect approach. This approach uses the equivalent single axle load (ESAL) as the unit for traffic loading, which implies that pavement deterioration caused by an axle is proportional to the fourth power of the axle weight. This paper answers the following question: how inaccurate are maintenance marginal cost estimates when a highway agency uses ESAL? We find that the inappropriate use of ESAL does not affect the sum of maintenance marginal cost prices paid by all vehicles (at current equilibrium); however, it impacts distribution among vehicles, which reduces equity and efficiency. 相似文献
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