The economic burden of depression among adults with rheumatoid arthritis in the United States

Aims: Depression is the most frequent comorbidity reported among patients with rheumatoid arthritis (RA). Comorbid depression negatively impacts RA patients’ health-related quality-of-life, physical function, mental function, mortality, and experience of pain and symptom severity. The objective of this study was to assess healthcare utilization, expenditures, and work productivity among patients with RA with or without depression.

Materials and methods: Data from adult patients who had at least two visits each related to RA and depression over a 1-year period were extracted from the Truven Health MarketScan research databases. Outcomes comprised healthcare resource utilization, work productivity loss, and direct healthcare costs comparing patients with RA with depression (n?=?3,478) vs patients with RA without depression (n?=?43,222).

Results: Patients with RA and depression had a significantly greater relative risk of hospitalization and number of all-cause and RA-related hospitalizations, utilization of emergency services, days spent in the hospital, physician visits, and RA-related surgeries compared with RA patients without depression. Patients with RA and depression had a higher risk of and experienced more events and days of short-term disability compared with patients without depression. The incremental adjusted annual all-cause and RA-related direct costs were $8,488 (95% CI = $6,793–$10,223) and $578 (95% CI = –$98–$1,243), respectively, when comparing patients with RA and depression vs RA only.

Limitations: The current analysis is subject to the known limitations of retrospective studies based on administrative claims data.

Conclusions: This study suggested increased healthcare utilization, work productivity loss, and economic burden among RA patients due to comorbid depression. These findings emphasize the importance of managing depression and including depression as a factor when devising treatment algorithms for patients with RA.     

Contracting and Reporting Conservatism around a Change in Fiduciary Duties*

We exploit an influential 1991 Delaware court ruling to examine simultaneously two types of conservatism that play important roles in resolving creditor–owner agency conflicts: contracting conservatism and reporting conservatism. The ruling expanded managerial fiduciary duties in favor of creditors for Delaware-incorporated firms in the vicinity of insolvency. In those firms, following the ruling, debt contracts are less likely to include conservative adjustments to accounting numbers used for covenant compliance (i.e., contracting conservatism decreases), while public financial reporting becomes more conservative (i.e., reporting conservatism increases). The decrease in contracting conservatism is concentrated in firms that exhibit a greater increase in reporting conservatism, suggesting that reporting conservatism is more cost-effective in resolving agency conflicts. In addition, the substitution effect is more pronounced in firms facing greater business uncertainty and firms with greater board independence.     

Who benefits from partial tax coordination?

In this paper, we investigate whether partial tax coordination is beneficial to countries within and outside a tax union, in which countries are supposed to compete in taxes and infrastructure. Our results demonstrate that a subgroup of countries agreeing on a common tax rate can harm both member and nonmember states. This is in contrast to the classical findings that partial tax harmonisation is Pareto improving. When a minimum tax rate is imposed within a tax union, we demonstrate that it does not necessarily improve the welfare of the member countries. Moreover, both the high‐tax and low‐tax countries can be worse off. This conclusion is at odds with the classical result that a high‐tax country benefits from the imposition of a lower tax bound.     

Using a dual-frame design to improve phone surveys on political attitudes: developing a weighting strategy for limited external information in Hong Kong

Quality & Quantity - In recent years, rapid increases in mobile phone ownership and decreases in landline users have led to potential biases in landline phone survey estimations. Mobile-only...     

基于社会服务的示范性高职院校师资队伍建设——以广东农工商职业技术学院为例

服务是高职院校的第一宗旨,而社会服务能力的高低关键在于示范院校师资队伍建设。该文从广东农工商职业技术学院社会服务能力的实际情况出发,分析了该院师资队伍建设存在的问题,认为,首先应通过体制创新,提高教师社会服务意识;其次通过不同途径打造"双师型"教师团队,从而提升教师社会服务能力。     

C++对象布局分析

分析了目前最为流行的面向对象的开发工具C 的对象布局，并进一步分析了其形成原因。     

利用规划放线成果修测城市地形图

一种根据规划放线验线成果修测地形图的方法——内业修测法，它可以及时反映城市地形地物的变化，保持地形图的现势性，较之传统的修测方法省时、省力、经济。     

Contagion or Inductance? Crisis 1997 Reconsidered

We provide the simple example of a refinancing game with incomplete information, where the lack of transparency is both necessary and sufficient for the propagation of local financial distress across disjoint financial networks. JEL Classification Number: F4.
And the truth shall make you free. John 8: 32     

关于开展航海职业教育扶贫工作的探讨

建设新农村的核心环节是提高农民收入。对贫困地区进行扶贫是党和政府解决贫困地区农民问题的重要手段之一,其中心工作是提高农民收入。通过开展航海职业教育扶贫工作可以有效地帮助转移农村富余劳动力,提高农民综合素质,增加农民收入,增强农民自身的造血功能,彻底改变贫穷的面貌;同时也有利于促进航运业和航海职业教育的发展。开展航海职业教育扶贫工作是一个多方合作共赢的过程。     

《技术制图》新旧标准对照

以对照方法介绍了《技术制图》与《机械制图》中三个基础标准的适用范围、采标情况及基本内容。