The economic burden of depression among adults with rheumatoid arthritis in the United States

Aims: Depression is the most frequent comorbidity reported among patients with rheumatoid arthritis (RA). Comorbid depression negatively impacts RA patients’ health-related quality-of-life, physical function, mental function, mortality, and experience of pain and symptom severity. The objective of this study was to assess healthcare utilization, expenditures, and work productivity among patients with RA with or without depression.

Materials and methods: Data from adult patients who had at least two visits each related to RA and depression over a 1-year period were extracted from the Truven Health MarketScan research databases. Outcomes comprised healthcare resource utilization, work productivity loss, and direct healthcare costs comparing patients with RA with depression (n?=?3,478) vs patients with RA without depression (n?=?43,222).

Results: Patients with RA and depression had a significantly greater relative risk of hospitalization and number of all-cause and RA-related hospitalizations, utilization of emergency services, days spent in the hospital, physician visits, and RA-related surgeries compared with RA patients without depression. Patients with RA and depression had a higher risk of and experienced more events and days of short-term disability compared with patients without depression. The incremental adjusted annual all-cause and RA-related direct costs were $8,488 (95% CI = $6,793–$10,223) and $578 (95% CI = –$98–$1,243), respectively, when comparing patients with RA and depression vs RA only.

Limitations: The current analysis is subject to the known limitations of retrospective studies based on administrative claims data.

Conclusions: This study suggested increased healthcare utilization, work productivity loss, and economic burden among RA patients due to comorbid depression. These findings emphasize the importance of managing depression and including depression as a factor when devising treatment algorithms for patients with RA.     

乡村振兴背景下西藏村庄规划的意义、考量和特色——以那曲市凯玛村为例

在全面实施乡村振兴战略的时代背景下,对包括西藏那曲市凯玛村在内的全国乡村进行村庄规划,不仅是非常必要的,也是极为现实的.从村庄规划是实施乡村振兴战略的首要前提、是加强国土空间治理的重要手段、是保护生态加快发展的基本路径三个方面,鲜明指出村庄规划的时代背景和现实意义;从生态环境和自然资源、产业结构与经济基础、村庄布局和人口密度、地理位置和交通状况、基础设施和公共服务、国家政策和内地帮扶六个方面,深入分析了那曲市凯玛村进行村庄规划的考量因素;从充分体现以人为本、民生为要,保护环境、生态优先,以经济为主题、以高质量发展为主线,尊重藏族文化、传承藏区民俗,居安思危、防灾减灾的五个理念,深刻阐述了凯玛村村庄规划的主要特征.     

基于社会服务的示范性高职院校师资队伍建设——以广东农工商职业技术学院为例

服务是高职院校的第一宗旨,而社会服务能力的高低关键在于示范院校师资队伍建设。该文从广东农工商职业技术学院社会服务能力的实际情况出发,分析了该院师资队伍建设存在的问题,认为,首先应通过体制创新,提高教师社会服务意识;其次通过不同途径打造"双师型"教师团队,从而提升教师社会服务能力。     

C++对象布局分析

分析了目前最为流行的面向对象的开发工具C 的对象布局，并进一步分析了其形成原因。     

教师情绪与课堂教学效果

教师情绪影响其行为和健康，也影响课堂教学效果。情绪对人的行为和活动的影响，主要通过情绪的动机性、信号性以及感染性功能起作用。教师掌握调适与消除消极情绪的方法、保持愉快的心境，有利于课堂教学效果的提高。     

政治体制上端改革:反腐败斗争的迫切需要

我国的反腐败已经进入了一个特殊的高原期,能否实现政治体制上端的重大改革,是决定中国反腐败能否实现突破的关键。政治体制上端改革要坚持三个不动摇、发展党内民主、完善人民代表大会制度和改革政党制度,可以建立"廉洁岛"式的政治特区。     

关于开展航海职业教育扶贫工作的探讨

建设新农村的核心环节是提高农民收入。对贫困地区进行扶贫是党和政府解决贫困地区农民问题的重要手段之一,其中心工作是提高农民收入。通过开展航海职业教育扶贫工作可以有效地帮助转移农村富余劳动力,提高农民综合素质,增加农民收入,增强农民自身的造血功能,彻底改变贫穷的面貌;同时也有利于促进航运业和航海职业教育的发展。开展航海职业教育扶贫工作是一个多方合作共赢的过程。     

中国银行业跨国并购的同心圆战略

当前的全球银行跨国并购浪潮，是在第五次全球企业并购浪潮下产生的，中国银行业要抓住这一历史机遇，通过实施“同心圆”战略，从企业竞争上升到产业竞争的高度去整合全球金融资源，建立起自己的产业价值链优势，在国际金融博弈中获得先发优势。     

关税、配额与补贴：效果分析与政策取向

关税、配额与补贴是一个国家用来保护国内市场、帮助国内厂商抵御国外对手竞争的常用措施.由于保护机制不同,关税、配额与补贴对不同利益主体的利益再分配会产生不同的影响.因此,一个国家可以根据其要保护的利益主体不同采取相应的保护措施.     

Innovative productivity and returns to scale in the pharmaceutical industry

This study shows that firms in the pharmaceutical industry experience decreasing returns to scale in R & D as the level of R & D expenditures rises. The paper presents the results of our study of the innovative output of 16 pharmaceutical firms over a 19 year period. Given the strong correlation between R & D budgets and firm size, our study suggests the wave of mergers in the industry may yield less innovative productivity than managers expect.