The economic burden of depression among adults with rheumatoid arthritis in the United States

Aims: Depression is the most frequent comorbidity reported among patients with rheumatoid arthritis (RA). Comorbid depression negatively impacts RA patients’ health-related quality-of-life, physical function, mental function, mortality, and experience of pain and symptom severity. The objective of this study was to assess healthcare utilization, expenditures, and work productivity among patients with RA with or without depression.

Materials and methods: Data from adult patients who had at least two visits each related to RA and depression over a 1-year period were extracted from the Truven Health MarketScan research databases. Outcomes comprised healthcare resource utilization, work productivity loss, and direct healthcare costs comparing patients with RA with depression (n?=?3,478) vs patients with RA without depression (n?=?43,222).

Results: Patients with RA and depression had a significantly greater relative risk of hospitalization and number of all-cause and RA-related hospitalizations, utilization of emergency services, days spent in the hospital, physician visits, and RA-related surgeries compared with RA patients without depression. Patients with RA and depression had a higher risk of and experienced more events and days of short-term disability compared with patients without depression. The incremental adjusted annual all-cause and RA-related direct costs were $8,488 (95% CI = $6,793–$10,223) and $578 (95% CI = –$98–$1,243), respectively, when comparing patients with RA and depression vs RA only.

Limitations: The current analysis is subject to the known limitations of retrospective studies based on administrative claims data.

Conclusions: This study suggested increased healthcare utilization, work productivity loss, and economic burden among RA patients due to comorbid depression. These findings emphasize the importance of managing depression and including depression as a factor when devising treatment algorithms for patients with RA.     

军民融合协同创新驱动产业园区高质量发展研究

军民融合产业园区高质量发展对于推进军民深度融合、在全国形成可复制可推广经验具有重要意义。军民融合协同创新通过促进新知识涌现、推进新产业集聚发展，最终汇聚经济发展新动能，驱动园区高质量发展。在提出军民融合协同创新驱动园区高质量发展的机理与组织框架基础上，将发展模式归纳为以分享经济为背景的资源共享模式、以新型研发机构为核心的第三方模式、以产业联盟为核心的产业链拓展模式和以交易平台为核心的“PPP”模式，最后提出相关对策建议。     

管理层权力制衡强度、债务约束与企业创新投资

企业创新是国家经济可持续增长的关键，受到管理层意愿的影响，因而需要对内部经营者的权力进行制衡。以2010-2018年我国A股上市公司为研究样本，实证检验管理层权力制衡强度对企业创新投资的影响，以及不同债务约束情境下高商业信用配置、高负债水平的调节效应，此外，还考察了产权性质的差异化影响。研究表明，管理层权力制衡强度越大，企业创新投资水平越高；高商业信用强化了该促进作用，而高负债水平弱化了该促进作用。进一步研究发现，管理层权力制衡强度与企业创新投资的关系在民企中更显著；国企能够更好地获得和运用商业信用，使其高商业信用对该关系的强化效应更显著；民企具有更强的债务约束，其高负债水平对该关系的弱化效应更明显。     

失败学习对企业绩效的影响机制研究

已有文献认为失败学习对企业绩效具有重要作用，但失败学习通过何种途径促进企业绩效提升的研究并不完善。基于失败学习理论，引入资源拼凑和机会识别作为中介变量，构建失败学习影响企业绩效的多路径模型，探索失败学习对企业绩效的驱动路径及内在机理。实证结果表明：失败学习对企业绩效具有显著积极作用，资源拼凑和机会识别分别在失败学习与企业绩效之间起中介作用，资源拼凑和机会识别在失败学习对企业绩效驱动过程中存在链式中介作用，战略柔性能够强化资源拼凑与企业绩效之间的关系，并正向调节资源拼凑的中介作用。研究结论拓展了失败学习对企业绩效的影响路径，对企业复苏和成长具有重要启示。     

普惠金融发展的地区差异、收敛性及影响因素研究*——基于中国省级面板数据的检验

本文利用2005—2016年省级面板数据，对我国各地区普惠金融发展水平进行测度，并在此基础上探讨其收敛性及影响因素。结果表明：（1）我国普惠金融发展水平在考察期内总体偏低，并且呈现出显著的地区差异性。（2）绝对β收敛在全国、中部和西部均存在，而东部不存在；条件β收敛在全国、东部和西部均存在，而中部不存在。（3）政府干预程度、市场化程度、人力资本质量、非正规金融以及外商直接投资对普惠金融发展均具有重要的影响。     

Structural estimation of behavioral heterogeneity

We develop a behavioral asset pricing model in which agents trade in a market with information friction. Profit‐maximizing agents switch between trading strategies in response to dynamic market conditions. Owing to noisy private information about the fundamental value, the agents form different evaluations about heterogeneous strategies. We exploit a thin set—a small sub‐population—to point identify this nonlinear model, and estimate the structural parameters using extended method of moments. Based on the estimated parameters, the model produces return time series that emulate the moments of the real data. These results are robust across different sample periods and estimation methods.     

Stochastic Payments per Claim Incurred

We propose a Bayesian model to quantify the uncertainty associated with the payments per claim incurred (PPCI) algorithm. Based on the PPCI algorithm, two submodels are proposed for the number of reported claims run-off triangle and the PPCI run-off triangle, respectively. The model for the claims amount is then derived from the two submodels under the assumption of independence between the number of incurred claims and the PPCI. The joint likelihood of the number of reported claims and claims amount is derived. The posterior distribution of parameters is estimated via the Hamiltonian Monte Carlo (HMC) sampling approach. The Bayesian estimator, the process variance, the estimation variance, and the predictive distribution of unpaid claims are also studied. The proposed model and the HMC inference engine are applied to to an empirical claims dataset of the WorkSafe Victoria to estimate the unpaid claims of the doctor benefit. The Bayesian modeling procedure is further refined by including a preliminary generalized linear model analysis. The results are compared with those in a PwC report. An alternative model is compared with the proposed model based on various information criteria.     

继续为多边贸易体制贡献中国力量

入世20年来,中国切实履行入世承诺,逐步从多边贸易体系的学习者、参与者成长为关键角色.中国经济的快速发展得益于多边贸易体系和经济全球化的深度发展,中国独特的经济体制与结构,为WTO以及多边贸易体系的稳定发展提供了源源不断的动力,为全球经济贸易发展注入持久动能,为发展中经济体参与多边贸易体系作出积极贡献.当前,经济全球化迈向新阶段,呈现出许多新的特征,而WTO本身也发生了结构性变化.中国作为推动WTO改革进程、权力结构调整和利益分配的关键力量,在坚定自身立场的同时,应及时顺应全球化变化,积极响应多边贸易治理新需求,为WTO改革贡献中国智慧、中国方案、中国力量,推动多边贸易体系行稳致远.     

江淮汽车成功开拓哈萨克斯坦市场的经验与启示

产能合作是当前和未来促进中哈两国经济协同发展的核心方式,江淮汽车成功进入哈萨克斯坦,对于推进两国制造业产能合作具有重要意义.充分利用国家政策、对接哈萨克斯坦汽车工业发展战略和市场需求、选择恰当国际市场进入模式和营销策略、培植核心竞争力以及积极应对哈萨克斯坦市场的激烈竞争是江淮汽车成功进入哈萨克斯坦市场的关键因素.我国企业应有效对接哈萨克斯坦经济战略,积极参与中哈产能合作;精准目标市场定位,优化产品结构;选择合适的市场进入模式,积极开展本地化生产;不断提升企业的核心竞争力.