The economic burden of depression among adults with rheumatoid arthritis in the United States

Aims: Depression is the most frequent comorbidity reported among patients with rheumatoid arthritis (RA). Comorbid depression negatively impacts RA patients’ health-related quality-of-life, physical function, mental function, mortality, and experience of pain and symptom severity. The objective of this study was to assess healthcare utilization, expenditures, and work productivity among patients with RA with or without depression.

Materials and methods: Data from adult patients who had at least two visits each related to RA and depression over a 1-year period were extracted from the Truven Health MarketScan research databases. Outcomes comprised healthcare resource utilization, work productivity loss, and direct healthcare costs comparing patients with RA with depression (n?=?3,478) vs patients with RA without depression (n?=?43,222).

Results: Patients with RA and depression had a significantly greater relative risk of hospitalization and number of all-cause and RA-related hospitalizations, utilization of emergency services, days spent in the hospital, physician visits, and RA-related surgeries compared with RA patients without depression. Patients with RA and depression had a higher risk of and experienced more events and days of short-term disability compared with patients without depression. The incremental adjusted annual all-cause and RA-related direct costs were $8,488 (95% CI = $6,793–$10,223) and $578 (95% CI = –$98–$1,243), respectively, when comparing patients with RA and depression vs RA only.

Limitations: The current analysis is subject to the known limitations of retrospective studies based on administrative claims data.

Conclusions: This study suggested increased healthcare utilization, work productivity loss, and economic burden among RA patients due to comorbid depression. These findings emphasize the importance of managing depression and including depression as a factor when devising treatment algorithms for patients with RA.     

军民融合协同创新驱动产业园区高质量发展研究

军民融合产业园区高质量发展对于推进军民深度融合、在全国形成可复制可推广经验具有重要意义。军民融合协同创新通过促进新知识涌现、推进新产业集聚发展，最终汇聚经济发展新动能，驱动园区高质量发展。在提出军民融合协同创新驱动园区高质量发展的机理与组织框架基础上，将发展模式归纳为以分享经济为背景的资源共享模式、以新型研发机构为核心的第三方模式、以产业联盟为核心的产业链拓展模式和以交易平台为核心的“PPP”模式，最后提出相关对策建议。     

电气继电保护装置的检修和运行维护探讨

在当前社会经济高速运转的时代,电力资源的需求量与日俱增,电力安全问题也越来越受到人们的重视,这就对电气继电保护装置提出了更高的要求,加强继电保护装置的检修和运行维护,可以极大地提升电力系统的运行效率,并保证电力运行的安全性.但是,就目前情况来说,我国电气继电保护装置的运行过程中还是存在一些故障问题,需要采取措施加以改进.基于此,本文将围绕电气继电保护装置运行中的常见故障展开分析,然后对继电保护装置的检修方法以及运行维护措施进行了详细的探讨与研究,以供相关人员参考.     

Research on Crop Irrigation Schedules Under Deficit Irrigation—A Meta-analysis

Water Resources Management - Increasing water consumption in agriculture due to global climate change has posed considerable challenges to food security, thus improving the efficiency of water...     

An Enhanced Beetle Antennae Search Algorithm Based Comprehensive Water Quality Index for Urban River Water Quality Assessment

Water Resources Management - Urban river not only has the important function in urban hydrological environment, but also is an area for entertainment. Water quality assessment is the core technique...     

管理层权力制衡强度、债务约束与企业创新投资

企业创新是国家经济可持续增长的关键，受到管理层意愿的影响，因而需要对内部经营者的权力进行制衡。以2010-2018年我国A股上市公司为研究样本，实证检验管理层权力制衡强度对企业创新投资的影响，以及不同债务约束情境下高商业信用配置、高负债水平的调节效应，此外，还考察了产权性质的差异化影响。研究表明，管理层权力制衡强度越大，企业创新投资水平越高；高商业信用强化了该促进作用，而高负债水平弱化了该促进作用。进一步研究发现，管理层权力制衡强度与企业创新投资的关系在民企中更显著；国企能够更好地获得和运用商业信用，使其高商业信用对该关系的强化效应更显著；民企具有更强的债务约束，其高负债水平对该关系的弱化效应更明显。     

设计部门现场管理的建设方案与实施

开展现场管理是提高企业管理水平、提高生产效率、提升产品质量、提升人员素质的有效途径.本文针对设计部门现场管理的建设思路与目标、实施过程进行了研究与实践,取得了良好的效果,为设计部门现场管理与建设提供了参考.     

生态护坡特点及关键技术探讨

随着我国基础设施建设深入践行"两山"生态环境理论,传统边坡防护不能满足新时代生态文明建设要求.文章介绍了植被对边坡的影响及岩质边坡生态护坡的常用方法,对岩质边坡的生态护坡特点进行了分析,对固土结构、基层材料、非生态装饰等关键问题进行了分析探讨,得到支护结构应与基层进行耦合分析、基层材料采用多孔材料有利于植被生长,基层填固应考虑与岩体嵌固附着作用,辅助装饰材料可达到较好的景观效果,具有一定工程社会意义,同时为类似生态护坡工程提供参考.