The economic burden of depression among adults with rheumatoid arthritis in the United States

Aims: Depression is the most frequent comorbidity reported among patients with rheumatoid arthritis (RA). Comorbid depression negatively impacts RA patients’ health-related quality-of-life, physical function, mental function, mortality, and experience of pain and symptom severity. The objective of this study was to assess healthcare utilization, expenditures, and work productivity among patients with RA with or without depression.

Materials and methods: Data from adult patients who had at least two visits each related to RA and depression over a 1-year period were extracted from the Truven Health MarketScan research databases. Outcomes comprised healthcare resource utilization, work productivity loss, and direct healthcare costs comparing patients with RA with depression (n?=?3,478) vs patients with RA without depression (n?=?43,222).

Results: Patients with RA and depression had a significantly greater relative risk of hospitalization and number of all-cause and RA-related hospitalizations, utilization of emergency services, days spent in the hospital, physician visits, and RA-related surgeries compared with RA patients without depression. Patients with RA and depression had a higher risk of and experienced more events and days of short-term disability compared with patients without depression. The incremental adjusted annual all-cause and RA-related direct costs were $8,488 (95% CI = $6,793–$10,223) and $578 (95% CI = –$98–$1,243), respectively, when comparing patients with RA and depression vs RA only.

Limitations: The current analysis is subject to the known limitations of retrospective studies based on administrative claims data.

Conclusions: This study suggested increased healthcare utilization, work productivity loss, and economic burden among RA patients due to comorbid depression. These findings emphasize the importance of managing depression and including depression as a factor when devising treatment algorithms for patients with RA.     

Bitcoin price and its marginal cost of production: support for a fundamental value

This study back-tests a marginal cost of production model proposed to value the digital currency Bitcoin. Results from both conventional regression and vector autoregression (VAR) models show that the marginal cost of production plays an important role in explaining Bitcoin prices, challenging recent allegations that Bitcoins are essentially worthless. Even with markets pricing Bitcoin in the thousands of dollars each, the valuation model seems robust. The data show that a price bubble that began in the Fall of 2017 resolved itself in early 2018, converging with the marginal cost model. This suggests that while bubbles may appear in the Bitcoin market, prices will tend to this bound and not collapse to zero.     

Organizational versus Market Knowledge: From Concrete Embodiment to Abstract Representation

Synopsis In contrast to the neoclassical economic presumption in favor of markets, we argue that organizations, not markets should be taken as our default assumption. We do so on information processing grounds. We distinguish between Zen and market Knowledge. The first is embodied and hard to articulate and the second abstract-symbolic. In human evolution, the first type of knowledge came first, and, on any pragmatic definition of knowledge, it still incorporates most of what we mean by the term. We take codification and abstraction as the two data processing activities that lead to the articulation of knowledge into an abstract-symbolic form. We develop a conceptual framework, the Information-Space (I-Space) to show how far the articulation of knowledge leads to its being shared. Whereas an unlimited sharing of information and knowledge leads to market-oriented outcomes, a more limited sharing leads to organizational outcomes. A market-oriented economics has tended to look to physics for its models; the field of organization theory has tended to look to biology. A more organization-oriented economics would thus look more to biology for its models.     

如何计算认股权证的资本成本

认股权证作为一种长期资金的筹资方式 ,其资本成本必须予以考虑。但是使用传统资本成本计算方法不能反映其真实成本。本文尝试使用B -S和CAPM模型来计算其资本成本 ,并用实例说明     

关于成本管理改革的探讨

随着社会主义市场经济和现代企业制度的逐步建立和完善，深化成本管理改革也日益成为一个突出而又迫切的问题。优胜劣汰是竞争的基本法则，企业要生存、求发展，就必须若练内功，采取各种措施降低成本，以低于竞争对手的成本进行生产经营，企业才能在竞争中立于不败之地。成本管理改革应对传统成本管理做出客观公正的评价，并在吸收西方先进的成本管理方法的基础上，正确把握成本管理改革的方向，为我国成本管理的理论研究和改革实践提供借鉴。     

农民工城乡迁移个人机会成本的构成及定量分析

农民工城乡迁移的个人机会成本可归纳为经济性个人机会成本、社会性个人机会成本和政治性个人机会成本三大类，基于笔者主持的1012名城乡迁移农民工的问卷调查，文章分析了这三类个人机会成本各自的构成，并对它们进行了定量分析。     

Goodwill—an Example of Puzzle-Solving in Accounting—a Reply

Grinyer and Russell's (G&R, 1992) contention that Ma and Hopkins (1988) have imposed the mutually exclusive rules of the valuation-based paradigm on the matching-based paradigm that underlies accounting practice is overly defensive and misguided. Our 1988 paper was an attempt to throw light on why there was so little agreement on the rules governing the treatment of goodwill. G&R's comment does not change our view that the only answer to the 'puzzle' lies in the lack of a full understanding of the nature of goodwill.     

供应链构建的机制分析

介绍了供应链的概念，交易成本经济学的基本理论，并把二者结合从经济学的角度分析了供应链构建的经济学机理，为供应链理论的发展提供了一个新的研究方向。     

商业银行成本控制方略

加入世贸组织后 ,我国商业银行将面临更加严峻的竞争环境。成本控制在商业银行经营管理中将发挥着越来越重要的作用。因此 ,有必要研究商业银行的成本控制方略     

Analysis on Sourcing Cost under E-commerce ＆ Sole Supplier

Supplier problem is a hotspot on the field of supply chain management. This paper makes hypotheses on supplier＇s delivery and the course of customers＇ ordering under the mode of e-commerce trade. Based on the existing （S, Q） model, this paper proposes the sourcing cost model with sole supplier under the situation of c-commerce, and analyzes the solving scheme in detail. This paper has established the foundation for further research.