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1.
We introduce a new type of heavy‐tailed distribution, the normal reciprocal inverse Gaussian distribution (NRIG), to the GARCH and Glosten‐Jagannathan‐Runkle (1993) GARCH models, and compare its empirical performance with two other popular types of heavy‐tailed distribution, the Student's t distribution and the normal inverse Gaussian distribution (NIG), using a variety of asset return series. Our results illustrate that there is no overwhelmingly dominant distribution in fitting the data under the GARCH framework, although the NRIG distribution performs slightly better than the other two types of distribution. For market indexes series, it is important to introduce both GJR‐terms and the NRIG distribution to improve the models’ performance, but it is ambiguous for individual stock prices series. Our results also show the GJR‐GARCH NRIG model has practical advantages in quantitative risk management. Finally, the convergence of numerical solutions in maximum‐likelihood estimation of GARCH and GJR‐GARCH models with the three types of heavy‐tailed distribution is investigated.  相似文献   
2.
Aims: The EINSTEIN-Extension trial (EINSTEIN-EXT) found that continued treatment with rivaroxaban for an additional 6 or 12 months (vs placebo) after 6–12 months of initial anticoagulation significantly reduced the risk of recurrent venous thromboembolism (VTE) with a small non-significant increased risk of major bleeding (none fatal or in critical site). This study aimed to compare total healthcare cost between rivaroxaban and placebo, based on the EINSTEIN-EXT event rates.

Methods: Total healthcare cost was calculated as the sum of treatment and clinical event costs from a US managed care perspective. Treatment duration and event rates were obtained from the EINSTEIN-EXT study. Adjustment on treatment duration was made by assuming a 10% non-adherence rate. Drug costs were based on wholesale acquisition costs. Cost estimates for clinical events (i.e. recurrent deep vein thrombosis [DVT], recurrent pulmonary embolism, major bleeding, clinically relevant non-major bleeding) were determined from the literature. Results were examined over a ±20% range of each cost component and over 95% confidence intervals (CIs) of event rate differences in deterministic (one-way) and probabilistic sensitivity analyses (PSA).

Results: Total healthcare cost was $1,454 lower for rivaroxaban-treated (vs placebo-treated) patients in the base-case, with a lower clinical event cost fully offsetting drug cost. The cost savings of recurrent DVT alone (–$3,102) was greater than drug cost ($2,723). Total healthcare cost remained lower for rivaroxaban in the majority (73%) of PSA (cost difference [95% CI]?=?–$1,454 [–$2,396, $1,231]).

Limitations: This study was conducted over the 1-year observation period of the EINSTEIN-EXT trial, which limited “real-world” applicability and examination of long-term economic impact. Assumptions on drug and clinical event costs were US-based and, thus, not applicable to other healthcare systems.

Conclusions: Total healthcare costs were estimated to be lower for patients continuing rivaroxaban therapy compared to those receiving placebo in VTE patients who had completed 6–12 months of VTE treatment.  相似文献   
3.
资源依赖型地区产业转型是保障国家资源安全和促进经济社会可持续发展的关键。我国资源依赖型地区数量多且分布广,现阶段此类地区开发阶段不同,所以进行产业转型的路径存在差异,其过程任重而道远。针对我国资源依赖型地区产业发展的现状进行分析并找出其问题,基于此,科学全面的探讨适合此类地区实现产业转型的五个战略,并进一步分别从地区资源开发阶段和地区利益相关主体两个维度,制定出符合资源依赖型地区产业转型的对策。  相似文献   
4.
对西部特色农业结构调整的思考   总被引:1,自引:0,他引:1  
西部开发战略的重要内容之一,就是开发西部特色农业,而开发西部特色农业首先要搞好农业结构调整.农业结构调整的内容有:农产品品种结构、农业生产内部结构、农产品加工转化增值和食粮主产区域结构的调整.农业结构调整也要注意一些问题,趋利避害,从实际出发,因地因时制宜,把握全局,平稳进行.  相似文献   
5.
以对照方法介绍了《技术制图》与《机械制图》中三个基础标准的适用范围、采标情况及基本内容。  相似文献   
6.
网上证券交易的国际比较和借鉴   总被引:2,自引:0,他引:2  
涂斌 《国际经贸探索》2003,19(4):33-35,53
网上证券交易是全球证券经纪业务发展的一大趋势,而我国在这方面尚处于初步发展阶段,文章主要阐述借鉴其他国家在网上证券交易的相关做法,结合我国现状提出对发展我国网上证券业务的建议。  相似文献   
7.
Yoshiharu Takamura 《Socio》2003,37(2):85-102
As a national project of Japan, plans for the relocation of several government agencies out of Tokyo have been ongoing. This paper is concerned with the problem of site selection for this project. The National Land Agency, the agency responsible for this project, has declared that the process of site selection should be rational, open to the public and easily understandable. In an effort to meet these requirements, we propose a consensus-making method for reaching a group decision, based on a combination of the analytic hierarchy process (AHP) and the Assurance Region model of data envelopment analysis (DEA). Several strategic uses of these methodologies, e.g., Delphi procedures, are also discussed. Based on these analyses, the “Wise Men” Committee for deciding the best site has chosen two from among ten contenders, one from the North-East and the other from the Central part of Japan, as candidates for the best relocation site. We could not discriminate between the two with respect to the multiple criteria chosen for evaluating sites. The Committee recommended the two sites to the Prime Minister at the end of December 1999. The Prime Minister reported this conclusion to the Diet. This topic is currently the focus of political discussions in the Diet. In this report, the authors summarize the decision-making processes that the Wise Men Committee followed, putting emphasis on the methodological aspects.  相似文献   
8.
区域金融创新体系研究   总被引:1,自引:1,他引:0  
陈晶莹 《改革与战略》2008,24(11):111-114
金融创新是金融发展的主要推动力之一,由于每一地区的经济、金融环境各不相同,有必要对区域金融创新体系的建立进行探索与研究,这样才能有针对性的对区域金融、经济的发展提出建设性的建议。因此,为了促进具有区域特色的金融创新的产生和发展,并使金融创新促进本地区的产业升级和经济发展,针对现有研究,文章对区域金融创新体系的概念界定、要素构成、运行机制、功能作用和构建中的实践问题等几个方面进行了分析研究。  相似文献   
9.
基于1978—2003年的统计数据,采用协整关系检验法和格兰杰(Granger)因果检验法对东北地区金融发展与产业结构优化之间的关系进行了实证检验。分析结果表明东北区域产业结构优化与金融发展之间存在长期动态均衡关系及单向因果关系,即金融发展对东北区域产业结构优化具有支持作用,从而为政府经济决策提供了政策依据。  相似文献   
10.
文章介绍了外向型经济的概念、内容、类型,分析了中部地区的基本情况及存在的问题,论述了外向型经济对中国中部崛起的影响。  相似文献   
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