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Bayesian MCMC Mapping of Quantitative Trait Loci in a Half-sib Design: a Graphical Model Perspective
N.A. Sheehan B. Gulbrandtsen M.S. Lund D.A. Sorensen 《Revue internationale de statistique》2002,70(2):241-267
Graphical models provide a powerful and flexible approach to the analysis of complex problems in genetics. While task-specific software may be extremely efficient for any particular analysis, it is often difficult to adapt to new computational challenges. By viewing these genetic applications in a more general framework, many problems can be handled by essentially the same software. This is advantageous in an area where fast methodological development is essential. Once a method has been fully developed and tested, problem-specific software may then be required. The aim of this paper is to illustrate the potential use of a graphical model approach to genetic analyses by taking a very simple and well-understood problem by way of example. 相似文献
3.
Abstract: This paper examines the characteristics of firms that account for deferred tax liabilities related to government investment grants under an extended adoption timing period. Not only the recognition but also the timing decision is associated with changes in future performance and changes in the debt structure. Recognisers outperform non‐recognisers in the future, while early recognition is related to post recognition performance but only for those firms that currently perform well. Changes in the balance sheet structure are also related to both decisions. Firms with recent increases in the debt level tend to postpone recognition, while currently well‐performing firms that increase their future debt level are less likely to recognise deferred taxes. 相似文献
4.
Leslie A. Hayduk 《Quality and Quantity》2006,40(4):629-649
Bentler and Raykov (2000, Journal of Applied Psychology 85: 125–131), and Jöreskog (1999a, http://www.ssicentral.com/lisrel/column3.htm, 1999b http://www.ssicentral. com/lisrel/column5.htm) proposed procedures for calculating R 2 for dependent variables involved in loops or possessing correlated errors. This article demonstrates that Bentler and Raykov’s procedure can not be routinely interpreted as a “proportion” of explained variance, while Jöreskog’s reduced-form calculation is unnecessarily restrictive. The new blocked-error-R 2 (beR 2) uses a minimal hypothetical causal intervention to resolve the variance-partitioning ambiguities created by loops and correlated errors. Hayduk (1996) discussed how stabilising feedback models – models capable of counteracting external perturbations – can result in an acceptable error variance which exceeds the variance of the dependent variable to which that error is attached. For variables included within loops, whether stabilising or not, beR 2 provides the same value as Hayduk’s (1996) loop-adjusted-R 2. For variables not involved in loops and not displaying correlated residuals, beR 2 reports the same value as the traditional regression R 2. Thus, beR 2 provides a conceptualisation of the proportion of explained variance that spans both recursive and nonrecursive structural equation models. A procedure for calculating beR 2 in any SEM program is provided. 相似文献
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For Poisson inverse Gaussian regression models, it is very complicated to obtain the influence measures based on the traditional
method, because the associated likelihood function involves intractable expressions, such as the modified Bessel function.
In this paper, the EM algorithm is employed as a basis to derive diagnostic measures for the models by treating them as a mixed Poisson regression
with the weights from the inverse Gaussian distributions. Several diagnostic measures are obtained in both case-deletion model
and local influence analysis, based on the conditional expectation of the complete-data log-likelihood function in the EM algorithm. Two numerical examples are given to illustrate the results. 相似文献
7.
This paper proposes a definition of relative uncertainty aversion for decision models under complete uncertainty. It is shown that, for a large class of decision rules characterized by a set of plausible axioms, the new criterion yields a complete ranking of those rules with respect to the relative degree of uncertainty aversion they represent. In addition, we address a combinatorial question that arises in this context, and we examine conditions for the additive representability of our rules. 相似文献
8.
会计只能提供相对相关和可靠的信息,在控制逆向选择和道德风险方面作用有限,形成了会计目标实现的障碍,这迫使投资者不得不去寻找其他信息渠道,以期更有效地决策。现金股利就是投资者寻找的信息渠道之一,它和会计信息在提高信息的相关性、可靠性以及控制逆向选择和道德风险方面共同发挥作用,并形成竞争态势,这种竞争态势实质上起到了对会计信息的治理作用。 相似文献
9.
《International Journal of Forecasting》2014,30(4):963-980
We extend the recently introduced latent threshold dynamic models to include dependencies among the dynamic latent factors which underlie multivariate volatility. With an ability to induce time-varying sparsity in factor loadings, these models now also allow time-varying correlations among factors, which may be exploited in order to improve volatility forecasts. We couple multi-period, out-of-sample forecasting with portfolio analysis using standard and novel benchmark neutral portfolios. Detailed studies of stock index and FX time series include: multi-period, out-of-sample forecasting, statistical model comparisons, and portfolio performance testing using raw returns, risk-adjusted returns and portfolio volatility. We find uniform improvements on all measures relative to standard dynamic factor models. This is due to the parsimony of latent threshold models and their ability to exploit between-factor correlations so as to improve the characterization and prediction of volatility. These advances will be of interest to financial analysts, investors and practitioners, as well as to modeling researchers. 相似文献
10.
利用农户土地流转问卷调查所得到的微观数据,采用统计分析、Probit multiple choicemodel方法,将农户经济行为中的保障性行为、投资行为、就业行为和产业选择行为引入土地流转的实证研究领域。研究结果显示:目前的土地流转多为暂时性流转,土地流转结构性供需矛盾严重;农户对土地的需求目的更多来自于保障性需要;农户的投资行为、就业行为、社会保障行为对土地流转有着重要影响。 相似文献