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1.
Aims: Depression is the most frequent comorbidity reported among patients with rheumatoid arthritis (RA). Comorbid depression negatively impacts RA patients’ health-related quality-of-life, physical function, mental function, mortality, and experience of pain and symptom severity. The objective of this study was to assess healthcare utilization, expenditures, and work productivity among patients with RA with or without depression.

Materials and methods: Data from adult patients who had at least two visits each related to RA and depression over a 1-year period were extracted from the Truven Health MarketScan research databases. Outcomes comprised healthcare resource utilization, work productivity loss, and direct healthcare costs comparing patients with RA with depression (n?=?3,478) vs patients with RA without depression (n?=?43,222).

Results: Patients with RA and depression had a significantly greater relative risk of hospitalization and number of all-cause and RA-related hospitalizations, utilization of emergency services, days spent in the hospital, physician visits, and RA-related surgeries compared with RA patients without depression. Patients with RA and depression had a higher risk of and experienced more events and days of short-term disability compared with patients without depression. The incremental adjusted annual all-cause and RA-related direct costs were $8,488 (95% CI = $6,793–$10,223) and $578 (95% CI = –$98–$1,243), respectively, when comparing patients with RA and depression vs RA only.

Limitations: The current analysis is subject to the known limitations of retrospective studies based on administrative claims data.

Conclusions: This study suggested increased healthcare utilization, work productivity loss, and economic burden among RA patients due to comorbid depression. These findings emphasize the importance of managing depression and including depression as a factor when devising treatment algorithms for patients with RA.  相似文献   
2.
COVID-19 put unprecedented external pressure on small businesses to adopt or increase use of social media while not all small businesses are internally ready for this rapid change. This study investigated the roles of external pressures and organizational culture of openness and learning in driving small retail business owners'/managers' social media use decisions by impacting their perceived usefulness and barriers, based on the innovation-decision process model from the diffusion of innovations theory and the theory of reasoned action. An online survey with structured measurements was administered to 411 U.S. small retail business owners/managers. Results from structural equation modeling revealed that external pressures positively influenced small business owners'/managers’ perceived usefulness and barriers and social media use intention. In addition, the culture of openness and learning positively influenced the perceived usefulness while mitigating the perceived barriers, thereby directly and indirectly influencing the social media use intention. Theoretical and managerial implications are discussed.  相似文献   
3.
以往关于时间压力对冲动性购买影响的研究结论具有两面性,即促进或抑制。文章引入交易效用和感知风险两个调节变量,通过两个实验探讨了时间压力对网络冲动性购买倾向影响的边界条件。首先,当交易效用较高时,时间压力的增加会导致其网络冲动性购买倾向的提高;而当交易效用较低时,时间压力的增加会导致其网络冲动性购买倾向的降低(实验一)。其次,当人们感知风险较低时,时间压力的增加会导致其网络冲动性购买倾向的提高;而当人们感知风险较高时,时间压力的增加会导致其网络冲动性购买倾向的降低(实验二)。研究结论可以帮助电商企业进一步了解消费者的冲动性购买行为,充分利用时间压力的影响,制定更灵活有效的促销策略。  相似文献   
4.
本文在体育锻炼能够增强体质,提高健康水平的生物学基础上和群众体育锻炼与专业训练的区别上,提出群众体育锻炼中如何合理安排运动量。  相似文献   
5.
本文通过分析2001至2004年上市银行年报非经常性损益的披露状况,对照监管部门法规,发现存在披露不充分的现象,对非经常性损益的确认也有理解偏颇,由此造成很多重大的可疑事项未计入非经常性损益。本文认为这对银行利润的真实性产生一定的影响,故建议政策制定者制定更详细的法规来规范披露行为,并就一些特殊事项做出释疑。  相似文献   
6.
This paper provides further evidence of price and volume effects associated with index compositional changes by analysing the inclusions (exclusions) from the French CAC40 and SBF120 indices, as well as the FTSE100. I find evidence supporting the price pressure hypothesis associated with index fund rebalancing, but weak or no evidence for the imperfect substitution, liquidity and information hypotheses. The results improve on recent evidence from the S&P500 index. The evidence for the FTSE100 additions shows, in particular, that markets learn about an imminent inclusion and incorporate this information into prices, even before the announcement date.  相似文献   
7.
廖敏 《基建优化》2006,27(2):125-126
地下水压力过大引起房屋地下室底板钢筋混凝土开裂,甚至被破坏,文章介绍采用钻孔桩加固技术进行结构处理,并新作防水层防水。  相似文献   
8.
The announcement of a convertible bond call is associated with an average contemporaneous abnormal stock price decline of 1.75% and an ensuing price recovery in the conversion period. A price fall and the subsequent recovery suggest price pressure as the explanation for the announcement effect. However, in general the option to convert is not exercised early and hence, the increase in the number of shares outstanding does not occur at the announcement date. Instead, this paper argues and provides evidence that hedging-induced short selling causes at least part of the short-run price pressure.  相似文献   
9.
Following Parsian and Farsipour (1999), we consider the problem of estimating the mean of the selected normal population, from two normal populations with unknown means and common known variance, under the LINEX loss function. Some admissibility results for a subclass of equivariant estimators are derived and a sufficient condition for the inadmissibility of an arbitrary equivariant estimator is provided. As a consequence, several of the estimators proposed by Parsian and Farsipour (1999) are shown to be inadmissible and better estimators are obtained. Received January 2001/Revised May 2002  相似文献   
10.
在人口老龄化背景下,地方政府的财政支出选择存在外在压力和内在激励。在理论分析人口老龄化影响地方财政支出偏好的作用机制基础上,采用中国省级财政数据检验老龄化背景下地方财政选择偏好。研究结果表明:地方政府财政支出是提高社会福利支出的外在压力和增强地方财政可持续性的内在激励的多路径效应结果,这种影响效应具有财政自给率和老龄化程度的非对称性。为了实现地方财政可持续性和有效应对老龄化社会的公众诉求压力,有必要尽快完善地方政府考核体系,完善地方公共支出的需求表达机制,改善当前财政支出责任地方化的状态。  相似文献   
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