Bayesian MCMC Mapping of Quantitative Trait Loci in a Half-sib Design: a Graphical Model Perspective

Graphical models provide a powerful and flexible approach to the analysis of complex problems in genetics. While task-specific software may be extremely efficient for any particular analysis, it is often difficult to adapt to new computational challenges. By viewing these genetic applications in a more general framework, many problems can be handled by essentially the same software. This is advantageous in an area where fast methodological development is essential. Once a method has been fully developed and tested, problem-specific software may then be required. The aim of this paper is to illustrate the potential use of a graphical model approach to genetic analyses by taking a very simple and well-understood problem by way of example.     

抓好速度耐力,突出强度,提高密度——高校中长跑训练方式之谈

高校进行中长跑训练是高校办高水平运动队的产物,运动员以在校大学生为主,运动员一边学习一边训练,属于＂边学边训性＂,运动训练具有较强的业余性。这一特点决定了高校运动队不能采用专业队的训练方法和标准,而应立足于自身的现实条件,去寻找适合自己的训练方法。高校中长跑项目的教学、训练应结合高校体育教育的特点,抓好速度耐力,突出专项,突出强度,提高密度,对运动员运动成绩的提高效果比较理想。     

中国区域经济差距研究综述

近年来中国东、中、西部地区经济差距有逐渐扩大的趋势,再次引起了政府和学术界的关注。中央在十八大明确提出要实施全国经济协调发展战略,让不同地区的人民都能实现中国梦。实现中国梦的第一前提是公平。而区域差距的扩大显然有违公平原则,在这个大背景下,缩小区域差距便成为中国当前时期一个亟待解决的艰巨任务。参考大量国内外研究区域经济差距的重要文献,按照逐步深入的顺序,从区域经济差距的研究方法到中国区域差距度量和变化趋势,再到中国区域经济差距的成因和对策,依次进行概括总结,并进行了相关评述,提出了一个缩小区域差距的新思路,作为下一步研究的重点方向。     

“室内设计原理”课程的教学改革探讨

＂室内设计原理＂课程是室内设计方向的主干课程之一,在专业课程教学中占有重要的地位。针对＂室内设计原理＂课程的教学现状及存在的问题,提出从教学方法、教学手段及考核评价机制入手对＂室内设计原理＂课程教学改革进行探讨,以期成为室内设计方向其他专业课程教学改革的重要切入点。     

2＋1教学模式转变下思政课教法改革思考

思政课在高职院校的教学中与本科院校的教学特点不同,在高职院校培养“应用型人才”的目标下,2＋1教学模式的转变是整体的趋势,在2＋1教学模式下,思政课教学可以分为理论教学与实践教学两个部分,在理论教学中可以采用启发式教学法、讨论式教学法、辩论式教学法、案例式教学法、演讲式教学法、角色互挟式教学法、专题式教学法;在实践教学中可以采用实地考察法、社会调查法、工作实践法,从而提高教学的实际效果。     

顺应理论下的翻译策略与方法——以《红楼梦》杨宪益英译本为例

Verschueren的顺应理论为从语用学的角度研究翻译提供了新的理论框架。翻译策略和方法的选择应该分别实现对宏观交际语境和微观语言语境的动态顺应。归化和异化是实现动态顺应的翻译策略,直译和意译则是翻译方法。《红楼梦》的杨宪益译本为顺应论视角下翻译策略和方法的成功选择提供了例证。     

关注“90后”大学生思想特点创新高校思想政治教育方法

＂90后＂是当前大学生的主体,因成长环境的不同造成了其身上具有不同于70、80年代大学生的特性,这给高校思想政治教育带来了现实的挑战。思想政治教育者应根据＂90后＂的思想特点,创新思想政治教育方法,增强思想政治教育的针对性和实效性。     

Detecting Abnormal Bid-Ask Spread: A Comparison of Event Study Methods

This study examines empirical issues associated with the use of bid-ask spreads in event studies. The simulation results indicate that the distribution of average standardized abnormal spread shows little deviation from normality. Simulation results also indicate that the widely used percent spread metric results in test statistics with low power. In contrast, use of a standardized raw spread metric and a simple mean-adjusted expectation model results in well specified and reasonably powerful Patell and Brown-Warner type test statistics. As the abnormal spread series is characterized by high first order serial correlation, it is important to adjust for this serial correlation when using multi-day event windows.     

Testing equality of variances in the analysis of repeated measurements

The problem of comparing the precisions of two instruments using repeated measurements can be cast as an extension of the Pitman-Morgan problem of testing equality of variances of a bivariate normal distribution. Hawkins (1981) decomposes the hypothesis of equal variances in this model into two subhypotheses for which simple tests exist. For the overall hypothesis he proposes to combine the tests of the subhypotheses using Fisher's method and empirically compares the component tests and their combination with the likelihood ratio test. In this paper an attempt is made to resolve some discrepancies and puzzling conclusions in Hawkins's study and to propose simple modifications.
The new tests are compared to the tests discussed by Hawkins and to each other both in terms of the finite sample power (estimated by Monte Carlo simulation) and theoretically in terms of asymptotic relative efficiencies.