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正交试验法优选黄芪西洋参口服液提取工艺的研究
引用本文:张明晶,迟云峰.正交试验法优选黄芪西洋参口服液提取工艺的研究[J].中国药物经济学,2012(4):24-25.
作者姓名:张明晶  迟云峰
作者单位:哈药集团制药六厂,黑龙江哈尔滨,150056
摘    要:目的 优选黄芪西洋参口服液的最佳提取工艺条件.方法 以总皂苷含量为指标,对影响提取的重要因素 A 加水量,B 提取次数,C 提取时间进行 L9(34)正交试验设计.结果 与结论最佳提取工艺为药材加 6 倍量水,提取 2 次,提取 1.5h/次,优选得到的工艺稳定可行.

关 键 词:黄芪西洋参口服液  总皂苷  正交试验

Optimization of the Extraction Process of Astragalus Membranaceus American Gineseng Oral Solution
Zhang Mingjing , Chi Yunfeng.Optimization of the Extraction Process of Astragalus Membranaceus American Gineseng Oral Solution[J].China Journal of Pharmaceutical Economics,2012(4):24-25.
Authors:Zhang Mingjing  Chi Yunfeng
Institution:Zhang Mingjing Chi Yunfeng
Abstract:Objective To study the best extraction process of Astragalus membranaceus American gineseng oral solution.Methods Using the orthogonal design which contained 3 factors(amount of water;extracted times;extracted hour)and 3 levels to detemine the content of total saponins as the index of evaluation.Results and conclusion The optimum conditions for the extraction of total saponins were 6 times of water,extracted twice and each time lasted 1.5 hours.The extraction process was stable and usable.
Keywords:Astragalus membranaceus American gineseng Oral Solution  Total saponins  Orthogonal design
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