| 通路相关不确定系数在化学品风险评定中的应用 |
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| 引用本文： | 龙再浩,马中春,陈小青.通路相关不确定系数在化学品风险评定中的应用[J].检验检疫科学,2011(6):52-55,17. |
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| 作者姓名： | 龙再浩 马中春 陈小青 |
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| 作者单位： | 宁波出入境检验检疫局; |
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| 基金项目： | 宁波市自然科学基金(2009A610177) |
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| 摘 要： | 制定化学品安全限量时需要使用不确定系数来减少不确定性，确保能充分保护暴露人群。本文简述人群包括成年人、老年人、儿童、新生儿和种族群体的单态性代谢和多态性代谢通路基础上不确定系数，它的应用将有助于提高我国化学品风险评定水平。
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| 关 键 词： | 化学品 毒代动力学 不确定系数 通路相关不确定系数 |
The Application of Pathway-Related Uncertainty Factor in Risk Assessment for Chemicals |
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| Long Zaihao,Ma Zhongchun,Chen Xiaoqing.The Application of Pathway-Related Uncertainty Factor in Risk Assessment for Chemicals[J].Inspection and Quarantine Science,2011(6):52-55,17. |
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| Authors: | Long Zaihao Ma Zhongchun Chen Xiaoqing |
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| Institution: | Long Zaihao,Ma Zhongchun,Chen Xiaoqing(Ningbo Entry-Exit Inspection and Quartine Bureau,Ningbo,Zhejiang,315012) |
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| Abstract: | When establishing the safe level of chemicals for risk assessment,the uncertainty factors will be applied to accommodate the uncertainty so as to make sure that the exposed-human population is adequately protected.This article introduced the PRUF of both monomorphic and polymorphic metabolism for adults,the old,children,neonates and ethnicity,which would be helpful to the improvement in the ability of risk assessment. |
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| Keywords: | Chemicals Toxicokinetics Uncertainty Factor Pathway-Related Uncertainty Factor |
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