疫苗药物经济学评价中有关成本和效果的测算方法探讨

与一般药物相比,疫苗具有外部性、保护率和作用时间不确定等特性,因此疫苗的经济学评价应当有其特殊性.本文回顾了近十几年世界有关疫苗经济学评价的研究报道,综合概括了疫苗经济学评价方法的最新进展.本文讨论的主要内容包括间接成本法、边际成本法、选择合适流行病学模型测量健康结果、成本和效果的贴现等.

Discussion the Methodology of Evaluating the cost and effectiveness in the economic evaluation of vaccines

Because there are some specific areas for the vaccines,comparing to classical,School of International Pharmaceutical Business,China Pharmaceutical University,Nanjing,211198,China general economic evaluation methodology does not suit to the vaccine.Reviewing the literature on the economic evaluation of vaccines in the last decades,and find some differences from cure intervention in some places.The indirect cost,marginal cost,choosing appropriate models to evaluate the effectiveness of the vaccine,estimating valuing health outcome and discounting of the input and outcome are discussed in this paper