Strategic design and operational management optimization of a multi stage physical distribution system

Design and management of logistic networks is one of the most critical issues in supply chain management. However, the literature does not contain any effective models, methods, and applications that simultaneously support management decisions in the strategic design of the distribution system, in the operational planning and organization of vehicles, and in container trips organization adopting different modes of transportation. The aim of this paper is to illustrate an original framework for the design and optimization of a multi echelon and multi level production/distribution system that combines mixed-integer linear programming modeling with cluster analysis, heuristic algorithms, and optimal transportation rules. A significant case study is illustrated revealing the effectiveness of the approach and tools proposed.