干扰素在儿科的临床应用

目的研究干扰素在儿科中的临床疗效。方法应用重组人干扰素α1b对上呼吸道、水痘、流行性感冒、手足口病、流行性腮腺炎患儿进行治疗,肌肉注射重组人干扰素α1b50～100U/次,每天一次,疗程为3-5天。结果重组人干扰素α1b治疗上呼吸道感染、水痘、流行性感冒、手足口病、流行性腮腺炎的总有效率分别为96.03%、92.08%、94.05%、94.05%、91.08%。有少数患儿出现发热、白细胞减少、血小板减少等异常,停药后即恢复正常,未发生其他明显的副作用。结论干扰素应用简单,疗效确切,且副作用少,在儿科有广泛的应用。

Interferon in pediatric clinical application

Objective:To investigate the application of interferon in pediatric clinical.Methods Recombinant human interferon α1b was used treat the upper respiratory tract,chicken pox,influenza,hand foot and mouth disease,mumps.Muscle injected recombinant human interferon α1b 50-100U/time,once a day,period of treatment for 3～5 days.Results:The total effective rate of them were 96.03%、92.08%、 94.05%、94.05%、91.08% respectively.A few occur in children with fever,Leucopenia,thrombocytopenia,abnormal,Withdrawal,return to normal,There was no other obvious side effects.Conclusion:interferon application simple,good efficacy and fewer side effects,and wide application in Pediatrics.