Biologische waardebepalingen van geneesmiddelen

The aim of standardization is to make sure that different batches of a drug do not vary in their potency. With most drugs this can be done by chemical methods, for a certain number of drugs however biological methods are still necessary. The best procedure to standardize a drug is to use a standard preparation. In this lecture it is discussed which demands must be made upon standard and the criterion. The measurement of the pyrogenic activity of drugs is discussed as an example.