| 凉粉草水煎液的高效液相色谱离子阱质谱分析研究 |
| |
| 引用本文： | 刘兰军,宋伟峰.凉粉草水煎液的高效液相色谱离子阱质谱分析研究[J].中国药物经济学,2013(3):61-63. |
| |
| 作者姓名： | 刘兰军 宋伟峰 |
| |
| 作者单位： | [1]佛山市禅城区澜石医院,广东佛山528041 [2]中山大学附属第三医院,广东广州510630 |
| |
| 摘 要： | 目的建立凉粉草水煎液化学成分的高效液相色谱离子阱质谱分析方法。方法凉粉草采用水煎煮,煎煮液采用高效液相色谱离子阱质谱对其主要化学成分进行分析研究。结果在优化的实验条件下,凉粉草水煎液的高效液相色谱质谱图中有16个明显的色谱峰,其中8个通过离子阱多级质谱进行了结构推测鉴定,5个通过对照品得到了化合物确证。结论高效液相色谱离子阱质谱是凉粉草化学成分分析鉴定的有效手段。
|
| 关 键 词： | 高效液相色谱 离子阱质谱 凉粉草 水煎液 化学成分 |
Identification of the Chemical Components in Water Extract of Mesona Chinensis Benth.by High-performance Liquid Chromatography Coupled With Ion Trap Mass Spectrometry |
| |
| Liu Lanjun SongWeifeng.Identification of the Chemical Components in Water Extract of Mesona Chinensis Benth.by High-performance Liquid Chromatography Coupled With Ion Trap Mass Spectrometry[J].China Journal of Pharmaceutical Economics,2013(3):61-63. |
| |
| Authors: | Liu Lanjun SongWeifeng |
| |
| Institution: | Liu Lanjun SongWeifeng |
| |
| Abstract: | Objective A high-performance liquid chromatography coupled with ion trap mass spectrometry （HPLC-IT-MS） method was established for the identification of the chemical components in water extract of Mesona chinensis Benth. Methods Mesona chinensis Benth. was extracted with water, and the extract was analyzed by HPLC-IT-MS. Results Under the optimized experimental conditions, 16 major peaks were obtained in the chromatogram, and 8 of them were identified by the MS and MSn information obtained by IT-MS. Moreover, 5 of the 8 identified compounds were confirmed according to the reference substances. Conclusion HPLC-IT-MS is a powerful tool for the rapid identification of the chemical components present in Mesona chinensis Benth. |
| |
| Keywords: | High-performance liquid chromatography Ion trap mass spectrometry Mesona chinensis Benth Water extract Chemical components |
| 本文献已被 维普 等数据库收录！ |
