Cost-effectiveness of selective internal radiation therapy using yttrium-90 resin microspheres in treating patients with inoperable colorectal liver metastases in the UK

Abstract

Objective:

Selective internal radiation therapy (SIRT) using SIR-Spheres® ⁹⁰Y-labeled resin microspheres has been shown to be a well-tolerated, effective treatment in patients with inoperable liver-dominant chemotherapy–refractory metastatic colorectal cancer (mCRC). This study estimated the cost-effectiveness of ⁹⁰Y-resin microspheres compared to best supportive care (BSC) from a UK perspective.