| 血清胱抑素C在2型糖尿病肾病早期诊断中的临床意义 |
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| 引用本文： | 柯箫韵. 血清胱抑素C在2型糖尿病肾病早期诊断中的临床意义[J]. 黄石理工学院学报, 2012, 28(3): 58-59,67 |
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| 作者姓名： | 柯箫韵 |
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| 作者单位： | 湖北理工学院医学院,湖北黄石,435003 |
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| 摘 要： | 为探讨血清胱抑素C在2型糖尿病肾病早期诊断中的临床意义,随机选择34例早期2型糖尿病肾病(T2DN)患者和34例无肾脏损伤的单纯2型糖尿病(T2DM)患者,分别作为DN组和DM组,另随机选择同期健康者34例为对照组,分别检测并分析3组患者的空腹血糖(FPG)、糖化血红蛋白(HbA1c)、血清胱抑素C(CysC)、血肌酐(SCr)和尿素氮(BUN)。结果为:DN组和DM组CysC水平明显高于对照组(P<0.05);DN组CysC水平明显高于DM组(P<0.05);DN组和DM组比较SCr和BUN无明显差异(P>0.05)。在2型糖尿病肾病早期诊断中,检测血清胱抑素C有一定的临床应用价值。
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| 关 键 词： | 糖尿病肾病 胱抑素C 糖化血红蛋白 血肌酐 尿素氮 |
Clinical Significance of Serum Cystatin C in the Early Diagnosis of Type 2 Diabetic Nephropathy |
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| KE Xiaoyun. Clinical Significance of Serum Cystatin C in the Early Diagnosis of Type 2 Diabetic Nephropathy[J]. Journal of Huangshi Institute of Technology, 2012, 28(3): 58-59,67 |
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| Authors: | KE Xiaoyun |
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| Affiliation: | KE Xiaoyun(School of Medicine,Hubei Polytechnic University,Huangshi Hubei 435003) |
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| Abstract: | To investigate the clinical significance of serum cystatin C in the early diagnosis of type 2 diabetic nephropathy,34 patients with early type 2 diabetic nephropathy(T2DN) and 34 patients with type 2 diabetes(T2DM) alone were randomly selected as DN group and DM group respectively.Meanwhile 34 healthy subjects were selected as control group.Fasting plasma glucose(FPG),glycosylated hemoglobin(HbA1c),serum cystatin C(cystatin C),serum creatinine(SCr) and blood urea nitrogen(BUN) were detected in the three groups.Results showed that CysC level in DN group and DM group was significantly higher than control group(P<0.05).CysC leve in DN group was significantly higher than DM group(P<0.05).SCr and BUN There was no significant difference in SCr and BUN between DN group and DM group(P>0.05).Conclusion can be concluded that serum cystatin C is a valuable reference in the early diagnosis of type 2 diabetic nephropathy. |
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| Keywords: | diabetic nephropathy cystatin C glycosylated hemoglobin serum creatinine blood urea nitrogen |
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