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蛇床子干乳剂的制备与稳定性考察
引用本文:姜霁洺,杨婧,邱金双,王艳宏,李永吉,王锐. 蛇床子干乳剂的制备与稳定性考察[J]. 黑龙江商学院学报, 2014, 0(4): 409-412
作者姓名:姜霁洺  杨婧  邱金双  王艳宏  李永吉  王锐
作者单位:黑龙江中医药大学药学院,哈尔滨150040
基金项目:黑龙江省教育厅科学技术研究项目(12531629).
摘    要:制备蛇床子干乳剂并考察其稳定性.超声法提取的蛇床子脂溶性提取物,应用冷冻干燥法制成蛇床子干乳剂,对其进行高温、高湿、强光照试验并预测其有效期.在高温、高湿试验中,蛇床子干乳剂外观颜色无明显变化,且其溶解度、质量以及质量分数变化不大.强光照试验中,蛇床子干乳剂的颜色有明显变化,指标含量也明显降低.有效期实验推测其在25℃,贮存期约为2 a.蛇床子干乳剂对于高温与高湿条件系统较稳定,但对光线敏感,需避光阴凉处保存.

关 键 词:蛇床子  干乳剂  稳定性考察

Preparation and stability test of cnidium monnieri dry emulsions
JIANG Ji-ming,YANG Jing,QIU Jin-shuang,WANG Yan-hong,LI Yong-ji,WANG Rui. Preparation and stability test of cnidium monnieri dry emulsions[J]. Journal of Harbin Commercial University(Natural Sciences Edition), 2014, 0(4): 409-412
Authors:JIANG Ji-ming  YANG Jing  QIU Jin-shuang  WANG Yan-hong  LI Yong-ji  WANG Rui
Affiliation:(School of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin 150040 , China)
Abstract:This paper investigated the preparation of cnidium monnieri dry emulsion and its stability .Alcohol extraction of cnidium monnieri was transformed to cnidium monnieri dry e-mulsion by freeze-drying method and the dry emulsion was detected under high temperature , high humidity , strong light , besides its predictive validity .The result showed that in the high temperature and high humidity conditions , the color , solubility , weight and content of cnidi-um monnieri dry emulsion had no significant changes .In contrast, in the strong light condi-tion, the color, solubility, weight and content of cnidium monnieri dry emulsion had signifi-cant changes .The validity experiments speculated that its storage period was about 2 years at 25 ℃.This paper showed that cnidium monnieri dry emulsion was relatively stable in high temperature and high humidity conditions , but was sensitive to light , needing preservation in dark and cool place .
Keywords:cnidium monnieri  dry emulsion  stability test
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