丙泊酚复合利多卡因静脉麻醉在高血压患者结肠镜检查中的应用

目的探讨丙泊酚复合利多卡因静脉麻醉在高血压患者结肠镜检查中的安全性及效果。方法回顾性分析47例高血压患者的结肠镜检查资料,将其分为常规组、无痛组。无痛组静脉缓慢注射丙泊酚和利多卡因混合液,使患者入睡后进镜检查。监测并记录两组在检查前、检查中、检查后的收缩压、舒张压、心率、血氧饱和度及镜检时间。无痛组记录麻醉诱导时间、苏醒时间、计算力及提问对答恢复正常时间。结果无痛组全部到达检查终点,常规组有2例未达到回盲部;无痛组镜检时间明显低于常规组,两组比较差异有统计学意义(P<0.05);无痛组的收缩压、舒张压、心率在检查中较检查前明显下降(P<0.05);常规组收缩压、舒张压、心率在检查中比检查前明显增高(P<0.05);两组检查结束后收缩压、舒张压、心率均恢复至检查前水平;血氧饱和度在两组的各个检查中无明显变化。无痛组麻醉诱导时间为(1.9±0.6)min、清醒时间为(6±5)min,计算力及提问对答恢复正常时间为(6±5)min。结论应用丙泊酚复合利多卡因静脉麻醉对高血压患者进行无痛结肠镜检查是可靠的。

Anesthesia via propofol and lidocaine combined intravenous injection in hypertensive patients during the process of Colonoscopy

Objective To investigate the safety and efficacy of anesthesia via propofol and lidocaine combined intravenous injection in hypertensive patients during the process of colonoscopy.Methods The colonoscopy data of 47 cases of hypertensive patients was retrospectively analyzed.The patients were divided into routine and painless groups.For the painless group,patients were intravenously administered propofol and lidocaine.After sleeping,the endoscopy study was performed.The systolic pressure,diastolic pressure,heart rate,oxygen saturation and examination time of the two groups were monitored and recorded,before,during and after the examination, respectively.The anesthesia induction time,recovery time,and calculating/answering recovering time of the painless group were recorded,respectively.Results Al patients in the painless group completed the examination, whereas the colonoscopy of 2 patients in the routine group did not reach the ileocecal;There was significant difference between two groups（P〈0.05）;for the painless group,the systolic and diastolic blood pressure,and heart rate during the inspection was significantly lower than that before the inspection（P〈0.05）;for the routine group,the systolic and diastolic blood pressure,and heart rate during the inspection was significantly increased compared with that before the inspection（P〈0.05）;after examination,the systolic and diastolic blood pressure and heart rate in both groups came back to the level before examination;the blood oxygen saturation did not shown significant difference during the examination for the two groups.For the painless group,the anesthesia induction time was（1.9 ±0.6）minutes;the awaking time was（6±5）minutes;the calculating/answering recovering time was （6± 5）minutes.Conclusion Anesthesia via propofol and lidocaine combined intravenous injection is reliable for the painless colonoscopy examination of patients with hypertension.