Evaluations of Drug-Testing Programs

In three experiments undergraduate students at an urban university evaluated drug-testing programs described in scenarios. Evaluations were inversely related to the false positive rate and were more favorable when a positive test result led to rehabilitation than when it led to termination of employment. Inconsistent effects on evaluations were observed for ability of the test to distinguish between previous drug use and current drug-based impairment, false negative rate, and implications of drug-impaired performance for public safety. There was also mixed evidence concerning the relation between evaluations and respondent belief in a just world. These results provide some support for Crant and Bateman's (1989) justice-based model of reactions to drug-testing and have implications for organizational drug-testing policies.     

Information Policy in Tournaments with Sabotage

Sabotage is one of the main problems of tournament‐like reward schemes. Workers who are leading in a tournament are more dangerous rivals, and are therefore sabotaged more heavily. This implies that there is an extra cost to becoming a leader and, hence, to choosing high productive effort in the early stages of a tournament. The incentives to exert productive effort are thereby reduced. We show that this problem can be solved by concealing intermediate information on the performances of workers (i.e., by clever information management). Moreover, we offer experimental evidence indicating that such information management does increase productive efforts.     

Kohlekraftwerke mit CO<Subscript>2</Subscript>-Abscheidung: Strategien,Rahmenbedingungen und umweltseitige Auswirkungen

A successful implementation of CO₂-capture in power plants is mainly depending on the energy political or economical environment. The future role of lignite and hard coal power production varies widely in presumed energy scenarios. This report considers the actual projections of BDEW. Increasing demand, the replacement of old plants and the compensation of efficiency losses due to CCS-technology cause highly ambitious expansion rates, assuming a retrofit time horizon of 10 years starting in 2020. The corresponding coal demand increases strongly. Therefore, a solely concentration of CO₂-reduction potential is not sufficient. Other environmental impacts triggered through emissions are low compared to the total German impacts. Nevertheless, the compliance with national ceilings for NO_x emissions for example can only be reached by compensation measures in other sectors.     

Cost-effectiveness of denosumab versus zoledronic acid for preventing skeletal-related events in the Czech Republic

Aims: This study assessed the cost-effectiveness of the subcutaneous RANKL inhibitor, denosumab, vs the intravenous bisphosphonate, zoledronic acid, for the prevention of skeletal-related events (SREs) in patients with prostate cancer, breast cancer, and other solid tumors (OST) in the Czech Republic.

Materials and methods: A lifetime Markov model was developed to compare the effects of denosumab and zoledronic acid on costs (including drug costs and administration, patient management, SREs, and adverse events), quality-adjusted life-years (QALYs), and incremental cost-effectiveness ratios from a national payer perspective. Different discount rates, time horizons, SRE rates, distributions, and nature (asymptomatic vs all SREs), and the inclusion of treatment discontinuation were considered in scenario analyses. The robustness of the model was tested using deterministic and probabilistic sensitivity analyses.

Results: Across tumor types, denosumab was associated with fewer SREs, improved QALYs, and higher total costs over a lifetime. The incremental cost per QALY gained for denosumab vs zoledronic acid was 382,673 CZK for prostate cancer, 408,450 CZK for breast cancer, and 608,133 CZK for OST. Incremental costs per SRE avoided for the same tumor type were 54,007 CZK, 51,765 CZK, and 94,426 CZK, respectively. In scenario analyses, the results remained similar to baseline, when different discount rates and time horizons were considered. At a non-official willingness-to-pay threshold of 1.2 million CZK, the probabilities of denosumab being cost-effective vs zoledronic acid were 0.64, 0.67, and 0.49 for prostate cancer, breast cancer, and OST, respectively.

Limitations: The SRE rates used were obtained from clinical trials; studies suggest rates may be higher in clinical practice. Additional evidence on real-world SRE rates could further improve the accuracy of the modeling.

Conclusions: Compared with zoledronic acid, denosumab provides a cost-effective treatment option for the prevention of SREs in patients with prostate cancer, breast cancer, and OST in the Czech Republic.     

1987: AIDS erreicht Deutschland

When, and how, was the issue of AIDS first established in the broad population in (West-)Germany? Our case study shows that 〉Bild〈 (the leading national tabloid newspaper) may have played an important part in establishing the issue. The people’s concern about AIDS runs astonishingly parallel with the intensity of coverage in 〉Bild〈. Even priming effects, such as the number of HIV-Tests performed, appear to be inspired by 〉Bild〈. At the same time, it becomes clear that coverage in 〉Bild〈 did not necessarily follow topical events.     

The Architecture Improvement Method: cost management and systemic learning about strategic product architectures

The architecture improvement method (AIM) is a method for multidisciplinary product architecture improvement, addressing uncertainty and complexity and incorporating feedback loops, facilitating trade-off decision making during the architecture creation process. The research reported in this paper demonstrates the ability of the AIM to contribute to cost management and systemic learning in the creation of strategic product architectures, throughout the entire product life cycle. Application of the method in five case studies within two divisions of Royal Philips Electronics shows that in cases of medium uncertainty, substantial cost management benefits can be achieved and that the AIM facilitates systemic learning through the accumulation of architectural competence, thus facilitating organizational memory.     

Monetary policy committees and interest rate setting

This paper shows that it is preferable for monetary policy to be conducted by a committee instead of a single policy maker if there is uncertainty about potential output. We examine three decision procedures - an optimal procedure, averaging and voting - and find that the latter is the appropriate way to reach decisions if policy makers are not equally skilled. Finally, we demonstrate that efficient decision procedures reduce the persistence of shocks.     

Manual dishwashing habits: an empirical analysis of UK consumers

This study presents an overview of the washing up behaviour of consumers in the UK. Peoples' individual attitudes were observed as were the amount of water and energy used, the time taken and the cleaning performance. Additionally, manual dishwashing was compared with the use of automatic dishwashers. Participants were recruited to represent all geographic regions of the UK as well as forming a representative cross‐section of the population. Each of the 150 participants washed a full load of soiled tableware based on the standard EN 50242 ‘Electric Dishwashers for Household Use – Methods for Measuring the Performance’. For comparison, the best selling dishwasher in the UK in 2007 was tested under the same conditions as those in the consumer trial. Additionally, consumers who owned a full‐size dishwasher were asked to load it to the point when they decided that the dishwasher was full. The study shows that these consumers, on average, used 49 l of water and 1.7 kWh of energy, whereas the dishwasher used 13 l of water and 1.3 kWh of energy on average for the same amount of dishes under the conditions tested. Statistical analysis showed that these differences are significant. The dishes washed by hand were found to be slightly less clean than dishes washed in a dishwasher. For washing a full dishwasher load by hand, the participants needed, on average, 60 min, while they only took 9 min on average to load and unload the same amount of dishes in a dishwasher. The average participants were able to fill almost the full load into the dishwasher (96% of the items as used in a test following EN 50242).