Representation and Educational Background of European Economists in Top Journals of Economics

We assess the contribution of European authors to 10 topjournals of economics from 1980 to 1998. Despite efforts on the European Union and national levels topromote academic excellence, European authors still play a minor role in top journals. Examining the development overtime we find little evidence for an increasing share of European contributions. Particular attention has been paidto the educational background of European authors. There is still a segmentation of academic education alonglanguage barriers in continental Europe. However, a considerable proportion of European authors has received a PhD from the US.     

2002～2005年间我国不同地区高校科技创新效率比较研究

利用SPSS13.0对2002～2005年间我国各省、市、自治区高校科技创新活动进行了聚类分析,并采用DEA的CCR模型对这4年中我国各省、市、自治区高校科技创新过程中经费支出,以及人员投入的效率问题进行了比较研究,结果发现有24个地区DEA有效,6个地区非DEA有效。最后给出了非DEA有效地区的改进方向。     

我国农业生态系统营养循环链的断裂与重建

完整的营养循环是农业生态系统健康、可持续发展的重要保障。我国传统农业属于环境友好型生态农业。农业生态系统的营养循环结构完整，持续健康、繁荣。但是，随着工业化、城市化、市场经济的发展以及农业耕作方式的转变，农业生态系统营养循环的结构遭到严重破坏，导致一系列资源、环境、经济与社会问题。通过秸秆还田以及城市生活废弃物（排泄物、厨房垃圾等）向农业生态系统的返还，重建农业生态系统完整的营养循环，是我国农业生态系统持续健康发展的必由之路。     

Health Damage of Air Pollution: An Estimate of a Dose–Response Relationship for the Netherlands

This paper estimates the dose-response relationship between air pollution and the number of work loss days for the Netherlands. The study is based on illness data (work loss days) for the Dutch labour population and average year concentrations of air pollution in 29 districts. The dose-response relationship has been estimated by means of two different techniques: the ordinary least squares method (OLS) and the one-way fixed-effects method (OWFEM), which we consider to be more adequate. In general health effects are much smaller when OWFEM is applied than if OLS is used. With OWFEM a significant relationship is found between sulphate aerosol (SO₄), ammonia (NH₃) and the number of work loss days (WLDs). Particulates (TSP), O₃ and SO₂ have no significant effect on the number of WLDs. These results differ from those obtained in studies in the United States, which indicate that particulates (TSP) and other small particles, ozone (O₃) and to a lesser extent SO₄ and SO₂ significantly influence the number of WLDs.     

高等职业技术学校学生岗位适应性研究

高等职业技术学校办学质量的途径和方法,即确立以素质教育为本位的职业教育内容,尤其要加强学生的心理素质教育.职业学校要做好师资配备工作,突出职业学校的办学特色;要协同家庭和企业,做好学生的职业就业指导工作,以出口带动入口,形成职业学校办学的良性循环.     

2017年北京社区卫生服务中心处方集中点评结果

目的汇总分析北京市16个区县近100家社区卫生服务中心处方抽样点评的结果,比较各区之间的差异,细化点评结果,促进全市合理用药。方法抽取2017年6月第2周,全门诊不包括草药处方,共计50189张处方,进行精细化集中点评。结果2017年北京16个区县社区卫生服务中心平均处方金额为160.07元,注射剂使用率为5.56%,全部基本药物占比为68.29%,处方的不合理率为8.8%。结论对于北京市社区卫生服务中心门诊处方集中点评最应改进的为统一点评标准,其次还应完善处方管理,强化药剂师自身的业务学习.     

A review and validation of overall survival extrapolation in health technology assessments of cancer immunotherapy by the National Institute for Health and Care Excellence: how did the initial best estimate compare to trial data subsequently made available?

Background: Validation of overall survival (OS) extrapolations of immune-checkpoint inhibitors (ICIs) during the National Institute for Health and Care Excellence (NICE) Single Technology Assessment (STA) process is limited due to data still maturing at the time of submission. Inaccurate extrapolation may lead to inappropriate decision-making. The availability of more mature trial data facilitates a retrospective analysis of the plausibility and validity of initial extrapolations. This study compares these extrapolations to subsequently available longer-term data.

Methods: A systematic search of completed NICE appraisals of ICIs from March 2000 to December 2017 was performed. A targeted search was also undertaken to procure published OS data from the pivotal clinical trials for each identified STA made available post-submission to NICE. Initial Kaplan-Meier curves and associated extrapolations from NICE documentation were extracted to compare the accuracy of OS projections versus the most mature data.

Results: The review identified 11 STAs, of which 10 provided OS data upon submission to NICE. The extrapolations undertaken considered parametric or piecewise survival models. Additional data cut-offs provided a mean of 18 months of OS beyond the end of the original data. Initial extrapolations typically under-estimated OS from the most mature data cut-off by 0.4–2.7%, depending on the choice of assessment method and use of the manufacturer- or ERG-preferred extrapolation.

Conclusion: Long-term extrapolation of OS is required for NICE STAs based on initial immature OS data. The results of this study demonstrate that the initial OS extrapolations employed by manufacturers and ERGs generally predicted OS reasonably well when compared to more mature data (when available), although on average they appeared to underestimate OS. This review and validation shows that, while the choice of OS extrapolation is uncertain, the methods adopted are generally aligned with later-published follow-up data and appear appropriate for informing HTA decisions.     

Definitions and progress of ecosystem health and ecological security

1. Introduction Development of human industrial civilization and predatory exploitation of natural resources have in- duced tremendous changes of ecological environment. In recent years, territorial and global environmental problems have increased, such as greenhouse effect, depletion of ozone, global warming, water scarcity, water pollution, acid rain, decrease of biodiversity, soil erosion desertification etc. These changes seriously intimidate the health and security of ecosystems, and dist…     

基于风景健康的海南省自贸区人居环境 空间研究

海南经过30年的经济特区建设已正式迈入自贸区建设的新时代，所面临的地区发展与生态维育矛盾逐步加剧。为保育海南优良的生态品质，提升海南人居环境空间质量，基于“健康、生态、人居”三元耦合与互动多赢的发展关系，提出与之适宜的风景园林健康理论；结合前人经验，以人居环境空间规划为切入点，解析人居环境空间研究内容。运用ArcGIS 10.2.2空间分析和Fragstats 4.2景观格局分析，解析海南省域三生空间敏感性、资源利用效率可持续性，以及资源服务范围与开发建设空间适宜性，结合人居环境空间发展特征，提出从全岛国土空间、资源统筹和空间营造3个方面进行规划引导，并提出以下观点：1)人类活动对资源环境和空间利用的合理性是有效保障海南人居环境空间的前提基础；2)遵循风景园林健康理论指导的全域国土空间规划、资源统筹规划和空间营造规划是提升海南人居环境空间的根本路径；3)“健康、生态、人居”三元耦合和互动多赢的关系均衡与协调是提升海南人居环境空间的终极目标。     

Managing academic innovation in Taiwan: Towards a ‘scientific-economic’ framework

Since the passage of the Science and Technology Basic Law in 1999, Taiwanese universities have taken a more “scientific-economic” approach to protect and commercialize their research. This research mainly examines innovation activities such as patenting, licensing, and incubated startups in the context of Taiwanese higher education institutions (HEIs). The “scientific-economic” framework used to analyze the strategic aspects influencing these academic innovations includes (1) intellectual property managerial capabilities, (2) the strength of external industrial partnerships, (3) the university entrepreneurial orientation, and (4) government research policy. Four hypotheses were developed. Data were collected via a questionnaire with all 122 HEIs in Taiwan surveyed.The research reveals that the aspects of intellectual property managerial capability, HEI-industry partnerships, and academic entrepreneurial orientation are useful to distinguish the university's innovation performance on patent grants, licensing incomes, and firm incubation. Also, government support on research plays a moderating role in academic innovation. Managerial and policy implications for managing innovation effectively in universities were drawn.