培养基灭菌温度与时间的选择

用湿热灭菌方法对培养基灭菌时,加热的温度和时间对微生物死亡和营养成分的破坏均有作用。由于培养基营养成分的破坏和菌体死亡都属于一级动力学反应,其反应速度常数与温度的关系皆可用阿累尼乌斯方程式表示;由此公式导出,当灭菌温度上升时,微生物杀死速率的提高要超过培养基成分的破坏速率的增加。所以采用高温快速灭菌方法,即可达到杀死培养基中的全部有生命的有机体,又可减少营养成分的破坏。     

三网融合解决方案的探讨

本文简单介绍了三网融合的含义、发展前景,分析了三网融合过程中的关键技术及存在的问题。现在兴起的IPTV对三网融合虽然是有力地推动,但是同时也指出三网融合的过程不是一蹴而就的。     

控制爆破快速清除氧化铝厂回转窑炉高温结疤

经过实践,找到了一种在保证不停产情况下对回转窑炉下料口结疤的快速装药爆破技术,在3分钟内能够完成药包投放和起爆工作,同时该方法也可用于指导该窑炉窑皮结疤的清理作业。文章叙述了如何在高温结疤部位吹孔,如何对炸药雷管实施有效隔热,如何快速装药起爆作业,同时介绍了施工过程中的作业注意事项和事故应急处理方案,为类似爆破作业提供参考经验。     

轨道车辆弯门快速设计系统研究

快速设计技术是在当今企业为快速响应市场对产品多样化需求的制造模式下提出并发展起来的,是以缩短产品开发周期为目的的一切设计技术与方法的总称。快速设计系统为了使产品快速设计成型并投入市场就必须要根据客户的需求快速地生成所需要的产品。对轨道车辆弯门快速设计系统进行了需求分析、总体方案设计以及研究与开发。为协助公司提高其快速反应能力奠定了良好的基础。     

几种真菌毒素快速检测技术分析

简便、快速、灵敏、准确、经济的真菌毒素分析方法是预防真菌毒素污染,保障食品安全的重要工具。近年来,随着色谱技术、免疫化学以及光、电、声等领域的不断发展,真菌毒素的检测技术出现了新的进展,特别是快速筛选和现场检测方面。综述了这些方面的一些进展,并重点介绍了基于抗原-抗体反应的快速检测方法,如试纸法、横向流动免疫检测技术、免疫生物传感器,以及其他正在发展的快速检测方法如光谱筛选方法等。这些方法将有望在今后的真菌毒素分析中得到广泛的应用。     

The potential value of rapid,cloud-enabled onsite testing for the diagnosis of rheumatoid arthritis in the United States

Abstract

Aims: Improvements in information technology have granted the recent development of rapid, cloud-enabled, onsite laboratory testing for rheumatoid arthritis (RA). This study aims to quantify the value to payers of such technologies.

Materials and methods: To calculate the value of rapid, cloud-enabled, onsite laboratory testing to diagnose RA relative to traditional, centralized laboratory testing, an Excel-based decision tree model was created that simulated potential cost-savings to payers who cover routine evaluations of RA patients in the US. First, a conceptual framework was created to identify the value components of rapid, cloud-enabled onsite testing. Second, value associated with patient time savings, savings on visit fees, change in treatment costs, and QALY improvements was measured, leveraging existing literature and information from an observational study. Lastly, these value components were combined to estimate the total incremental value accruing to payers per patient-year relative to centralized laboratory testing.

Results: Rapid, cloud-enabled, onsite testing is estimated to save one office and 1.81 laboratory visits during the evaluation period for the average patient. Results from an observational study found that rapid, cloud-enabled testing increased the likelihood of completing diagnostic orders from 84.5% to 97%, resulting in an increased probability of early treatment (3.5 percentage points) with disease-modifying anti-rheumatic drugs among patients eligible for treatment. The combined total value was $5,648 per evaluated patient-year. This value is primarily attributed to health benefits of early treatment ($5,048), fewer visit payments ($459), and patient time savings due to fewer office ($216) and laboratory visits ($255).

Limitations and conclusions: Data on the impact of rapid, cloud-enabled, onsite testing on patient health, care delivery, and clinical decision-making is scarce. More robust real-world data would confirm the validity of our model. Rapid, cloud-enabled, onsite testing has the potential to generate significant value to payers.     

快速掘进技术在突出煤层的应用

九里山矿作为突出矿井之一,为了保证其开采的安全和高效,在实际的开采中使用了水力挤出快速掘进方法,取得了很大的成效。我们对这一矿井的开采方式进行全面的探究,以期能使今后的矿井开采更加的顺利、安全、高效。     

乌鲁木齐市快速公交系统开发研究

在对乌鲁木齐市公交系统研究的基础上,通过技术方案的对比分析,设计出新型的适用于乌鲁木齐市现况的快速公交系统方案。     

Redistributive effects of bus rapid transit (BRT) on development patterns and property values in Seoul, Korea

This study investigates the redistributive effects of Seoul's bus rapid transit (BRT) system on development patterns and property values using an urban simulation model. The Seoul Metropolitan Integrated Urban Model (SMIUM) combines the Seoul metropolitan input-output model with random utility-based location choice models and endogenous real estate markets.The major findings of this study can be highlighted as follows. First, Seoul's BRT contributes to increased development density in urban centers, acting as a centripetal force to attract firms from the suburbs into urban cores and supporting arguments for Smart Growth proponents. Second, unlike its redistributive effects on nonresidential activities, the BRT has a limited effect on the redistribution of residential activities, implying that residential locations are less sensitive to accessibility improvements made by the BRT than are nonresidential locations. Third, reflecting the transferred space demands from the suburbs to the urban cores, the CBD reaps the highest property value gains, while all of the outer ring zones suffer from reduced property values.     

先进制造工艺技术及先进制造技术的未来

概述了当前各种先进制造工艺技术的特点和发展水平及先进制造技术的发展前景和制造业存在的问题及其对策。