The economic burden of depression among adults with rheumatoid arthritis in the United States

Aims: Depression is the most frequent comorbidity reported among patients with rheumatoid arthritis (RA). Comorbid depression negatively impacts RA patients’ health-related quality-of-life, physical function, mental function, mortality, and experience of pain and symptom severity. The objective of this study was to assess healthcare utilization, expenditures, and work productivity among patients with RA with or without depression.

Materials and methods: Data from adult patients who had at least two visits each related to RA and depression over a 1-year period were extracted from the Truven Health MarketScan research databases. Outcomes comprised healthcare resource utilization, work productivity loss, and direct healthcare costs comparing patients with RA with depression (n?=?3,478) vs patients with RA without depression (n?=?43,222).

Results: Patients with RA and depression had a significantly greater relative risk of hospitalization and number of all-cause and RA-related hospitalizations, utilization of emergency services, days spent in the hospital, physician visits, and RA-related surgeries compared with RA patients without depression. Patients with RA and depression had a higher risk of and experienced more events and days of short-term disability compared with patients without depression. The incremental adjusted annual all-cause and RA-related direct costs were $8,488 (95% CI = $6,793–$10,223) and $578 (95% CI = –$98–$1,243), respectively, when comparing patients with RA and depression vs RA only.

Limitations: The current analysis is subject to the known limitations of retrospective studies based on administrative claims data.

Conclusions: This study suggested increased healthcare utilization, work productivity loss, and economic burden among RA patients due to comorbid depression. These findings emphasize the importance of managing depression and including depression as a factor when devising treatment algorithms for patients with RA.     

乡村旅游核心利益相关者协调发展评价研究——以青海省海东市互助土族自治县小庄村为例

文章基于利益相关者理论的视角，选取青海省海东市互助县小庄村为案例地，通过田野调查和文献梳理分析出核心利益相关者的利益诉求和矛盾冲突，并构建乡村旅游核心利益相关者协调发展评价体系，采用EWM-Fuzzy综合评价模型和灰色关联模型对地方政府、旅游企业、社区居民及外来游客四类核心利益相关者利益诉求的紧急程度、利益关系协调发展状态及整体协调发展关系进行测评分析。研究表明，小庄村四类核心利益相关者对不同利益诉求的整体感知较好，不同利益诉求的紧急程度和协调发展状态均存在如下较大差异:四类核心利益相关者的利益诉求主要处于中度协调和轻度协调两种发展状态，优质协调发展状态的利益诉求表现相对较少，且存在濒临失调发展状态的利益诉求表现；小庄村旅游核心利益相关者相互间的协调发展关系呈现出多元化的发展状态，地方政府、旅游企业同其他利益相关者的利益关系协调发展的影响大小顺序完全一致，地方政府、社区居民同其他利益相关者的利益关系协调发展的影响大小顺序相对应，而外来游客、社区居民同其他利益相关者的利益关系协调发展的影响大小顺序基本相反；小庄村旅游核心利益相关者协调发展路径组合未达到纳什均衡状态，其协调发展模式为非对称互惠协调发展模式。上述验证结果与小庄村旅游发展的实际情况基本吻合，证明了评价体系的科学性。     

高分1号冬小麦解译面积核算方法研究

[目的]以高分1号(GF-1)融合2m卫星遥感影像为基础数据源,结合土地利用现状数据、高分多源遥感影像和地面样方等数据,对冬小麦分类提取中存在的面积误差问题进行研究和分析。[方法]文章以河南省永城市为研究区,在冬小麦提取结果聚类处理基础上,基于线性地物缓冲区数据,采用GIS空间运算实现线性地物面积扣除,接着分析了样方数据和土地利用现状数据再扣除零星地物面积比例上的差异,并采用样方零星地物平均扣除系数对全市各乡镇耕地与非耕地中冬小麦提取面积进行了相关统计和误差分析。[结果]永城市冬小麦最终解译面积11. 29万hm~2,其中线性地物和零星地物扣除面积分别为6 613. 08hm~2和3 875. 22hm~2,占研究区冬小麦解译面积的5. 86%和3. 32%,与统计上报数据相比,其处理前后误差由14. 12%降低至4. 41%,有效地提高冬小麦提取面积精度。[结论]误差来源分析与修正对冬小麦解译面积核算精度具有重要影响,该研究为县级区域尺度下冬小麦面积提取核算提供了思路和借鉴。     

A Real Options Model of Real Estate Development with Entitlement Risk

Most development projects encounter a highly uncertain entitlement process that is largely uncontrollable by developers. In this study, entitlement is modeled as a separate stage within a compound real option, where developers begin with minimal control (maximum risk) and each successful stage increases control (decreases risk). We solve the model analytically, provide three‐dimensional numerical comparisons, and empirically test the model's predictions using hand collected rezoning petitions. Our main result refines the classic development option model: developers first invest early (secure entitlements) in order to obtain the option to subsequently delay investment (construct the optimal building at the optimal time).     

A Note on a Framework for Valuation Ratios Based on Fundamentals*

Valuation ratios divide stock price by accounting metrics such as earnings, earnings growth, and book value. This study adapts the general valuation framework in Ohlson and Juettner-Nauroth (2005) and Ohlson (2005) to present a unified approach for developing valuation ratios based on fundamentals, referred to as fundamental valuation ratios. One starts with a valuation model that is driven by an accounting metric a and its abnormal growth, then divides the valuation model by a to get a fundamental valuation ratio. For any valuation ratio, one can find a corresponding fundamental valuation ratio, as long as the valuation model is based on the same metric a as the valuation ratio denominator.     

Childhood adversity and the propensity for entrepreneurship: A quasi-experimental study of the Great Chinese Famine

Studies on the determinants of entrepreneurship emphasize that challenged adults tend to become entrepreneurs. However, research has not addressed the childhood origins surrounding the propensity for entrepreneurship. This article links childhood adversity to the propensity of individuals to become migrant entrepreneurs later in life. We test hypotheses derived from this theory in the context of whether, and when, children who survived the Great Chinese Famine of 1959–1961 became migrant entrepreneurs. Results strongly indicate that those who survived greater hardship during the Famine are more likely to become entrepreneurs, especially when they were younger during the famine years. We also find that being younger at the time of migration increased the likelihood of becoming entrepreneurs in their new locale. Overall, this study casts light on why, how and when childhood adversity shapes the propensity for entrepreneurship.     

高质量发展导向下国家级新区空间优化——基于双效评价与四分图分析

国家级新区是国家区域空间生产策略的体现,新时期高质量发展对其空间优化提出新要求.基于产城融合、区域协同与双效提升的高质量发展目标体系,构建国家级新区空间优化效果—效率双评价四分图模型,比较分析浦东、滨海等6个国家级新区2011～2017年空间优化水平.研究发现:(1)6个国家级新区空间优化水平整体呈现马太效应,低效果—低效率的新区间差距呈扩大趋势.(2)国家级新区空间优化水平存在南高北低的区域差异,南部4个新区中,2010年前成立的新区空间优化水平更高.(3)国家级新区空间优化效果与效率总体均值呈现类雁形与"乀"形变化.从以动态评价赋能精准施策、以绿色创新推动产城融合、以开放协调带动新区合作、以双效提升引导差异化发展等方面提出国家级新区空间优化的建议.     

An Empirical Analysis of Green Experiential Loyalty: A Case Study

The purpose of this study is to elaborate the structural relationships among the experiential quality dimensions, experiential trust, emotional attachment, experiential image, switching experience, experiential satisfaction, and experiential loyalty from the green perspective. The study findings are based on structural equation modeling (SEM) analysis of a convenience sample of 560 customers at one green restaurant in Taipei City, Taiwan. The findings show that investing resources in an increase in the experiential quality dimensions and a decrease in green switching experience is useful to enhance green experiential trust, green emotional attachment, green experiential image, green experiential satisfaction, and green experiential loyalty.     

关系质量对企业知识创造绩效的作用机理：一个被调节的中介模型

基于嵌入性视角，分别引入知识转移、合作模式作为中介变量和调节变量，深入探究关系质量影响企业知识创造绩效的内在机理。利用277份来自全国多地的制造业及高新技术企业调查问卷，采用多元回归方法进行实证研究。结果表明：经济型和社会型关系质量均正向影响企业知识创造绩效；社会型关系质量通过元素知识和架构知识转移正向影响企业知识创造绩效。在契约治理模式下，经济型关系质量更倾向于通过元素知识转移正向影响企业知识创造绩效；在股权治理模式下，社会型关系质量更倾向于通过架构知识转移正向影响企业知识创造绩效。     

基于社会服务的示范性高职院校师资队伍建设——以广东农工商职业技术学院为例

服务是高职院校的第一宗旨,而社会服务能力的高低关键在于示范院校师资队伍建设。该文从广东农工商职业技术学院社会服务能力的实际情况出发,分析了该院师资队伍建设存在的问题,认为,首先应通过体制创新,提高教师社会服务意识;其次通过不同途径打造"双师型"教师团队,从而提升教师社会服务能力。