Why Regenerative Agriculture?

Regenerative agriculture is both an attitude and a suite of practices that restores and maintains soil health and fertility, supports biodiversity, protects watersheds, and improves ecological and economic resilience. It focuses on creating the conditions for life above and below ground and takes its cues from nature, which has a very long track record of successfully growing things. By re-carbonizing soils via photosynthesis and biology, particularly on degraded land, regenerative agriculture can also sequester increasing quantities of atmospheric carbon (CO₂) underground, making it a low-cost “shovel-ready” solution to climate change. Its multiple co-benefits, including the production of healthy, nutritious food, means it will be a critical component of our response to rising climate instability.     

Readying a region: temporally exploring the development of an Australian regional quadruple helix

Understanding how innovation drives regional development has important economic and social outcomes. Models such as Smart Specialisation and the quadruple helix are increasingly adopted given their sensitivity to place-based contexts. But although innovation processes are dynamic and facilitated by individuals’ interactions, our understanding of how these connections are developed and sustained during helix collaboration development remains under-investigated. This research adopts an action research approach, focused on a regional Australian case study, to test a multi-disciplinary conceptual framework exploring key human-centred, micro-processes driving quadruple helix development: trust building; power relationships; regional readiness; and time and sphere centrality. The findings demonstrate the interactive nature of these processes, with trust-building facilitating the deployment of power bases by critical innovation agents which then foments regional readiness for change, subsequently driving the helix spheres towards overlap. These processes were also driven by changing sphere centrality and unique regional temporal structures. Practically, these outcomes offer insights into the human capital dynamics of regional helix collaborations, particularly for identifying the key individuals required to drive their development.     

Benefits and challenges of conducting multiple methods research in marketing

Using multiple methods to study a phenomenon is proposed to produce results that are more robust and compelling than single method studies. This research note investigates the implementation of multiple methods research in marketing. In the main study, we conducted a content analysis of articles published in five leading marketing journals from 1990 to 2008: Journal of the Academy of Marketing Science, Journal of Consumer Research, Journal of Marketing, Journal of Marketing Research, and Marketing Science. To aid in interpretation of findings from the content analysis, we gathered verbal data from authors of recent multiple methods studies to gain further insight into the benefits and challenges of conducting and publishing multiple methods research.     

Overall survival,costs, and healthcare resource use by line of therapy in Medicare patients with newly diagnosed metastatic urothelial carcinoma

Aims: Medicare patients with metastatic or surgically unresectable urothelial carcinoma (mUC) often receive platinum-based chemotherapy as first line of therapy (LOT), but invariably progress, requiring additional LOTs and healthcare resource use (HCRU). To better understand the evolving mUC treatment landscape, the economic burden of chemotherapy-based mUC treatments among US Medicare patients was estimated.

Methods: Newly diagnosed Medicare patients with mUC were identified from the Surveillance, Epidemiology, and End Results (SEER)-Medicare database. Patients were followed from diagnosis to death, disenrollment, or end of study to characterize LOTs (first [LOT1], second [LOT2], and third or greater [LOT3+]). Kaplan-Meier methods were used to estimate overall survival (OS) by LOT. HCRU and mean costs were reported over the follow-up period, LOT duration, and maximum LOT received.

Results: Among 1,873 eligible patients with mUC (median age?=?77?years; median follow-up?=?7.5?months), 1,035 (55%) received no chemotherapy. Among chemotherapy-treated patients, 61% had LOT1 only, 25% had LOT1 and LOT2 only, and 14% had LOT3+. Median OS was 8.1?months, range was 4.3 (untreated) to 29.8 (LOT3+) months. HCRU frequency increased with additional LOTs. Mean cumulative per-patient cost was $82,912 for all patients, increasing with additional LOTs (untreated?=?$57,207; LOT1?=?$99,213; LOT2?=?$125,190; LOT3+?=?$163,884). Mean per patient per month cost was $18,827 for all patients, decreasing with increasing number of LOTs received (untreated?=?$27,211; LOT1?=?$9,601; LOT2?=?$7,325; LOT3+?=?$6,017).

Limitations: Potential for treatment misclassification when using the algorithm defining LOTs and non-generalizability of results to younger patients.

Conclusions: Over 50% of Medicare patients with mUC received no chemotherapy. Among chemotherapy-treated patients, most received only one LOT. Additional LOTs led to higher mean costs and HCRU, but as patients were followed longer, monthly costs decreased. As treatments evolve to include immuno-oncology agents, these findings provide a clinically relevant economic benchmark for mUC treatment across different traditional LOTs.     

The Organization of Innovation Brokers: An International Review

Research on networks of innovation has typically focused on relationships of competition and collaboration between firms in the network, sometimes extending the analysis to sources of new ideas such as universities. More recently, attention has been paid to the activities of intermediaries in such networks, which facilitate the innovation process, which are positioned between the sources and users of innovations. This paper focuses on the organization of a distinctive type of intermediary, which we have defined as an innovation broker, by providing an analysis of 10 case studies of organizations dedicated to innovation broking from around the world. Innovation brokers in our definition are organizations that are founded especially to undertake an intermediary role, rather than performing that role as a by-product of their principal activities. The results of this analysis suggest that the key role played by innovation brokers in the innovation process is the independent validation of new ideas, thereby facilitating diffusion. In order to carry out this task, innovation brokers are organized on a not-for-profit basis, typically as a public-private partnership. The paper concludes by discussing the implications of the findings for innovation theory and research in networks of innovation.     

Inter-vivos Transfers and Exchange

Most parents divide their bequests equally among their children, whereas inter-vivos transfers are usually unequal. We propose that exchange is better for inducing inter-vivos transfers than bequests. Inter-vivos transfers can be adjusted quickly to the amount of care, are less costly than writing a will, and can be kept secret from other family members and the public. The results from national longitudinal data show that, as expected, if a parent gives any inter-vivos transfers, she is more likely to give to children who provide informal care. Informal care has no effect on the equality of intended bequests.     

The influence of hospitable design and service on patient responses

ABSTRACT

A study of 216 respondents examined a medical center environment’s influence on patient responses. A stimulus–organism–response (S-O-R) model was adapted to the theory that more hospitable healthcare servicescape elements will affect patients’ overall satisfaction with healthcare experience, loyalty intentions, and willingness to pay out-of-pocket expenses for healthcare services. Servicescape elements included atmospherics of the healthcare environment, service delivery by healthcare staff, physical design of the healthcare environment, and wayfinding. Results of structural equation modeling confirmed that the four servicescape elements – had a significant impact on patients’ overall satisfaction with the healthcare experience. Furthermore, overall satisfaction with the healthcare experience predicted patients’ loyalty intentions and willingness to pay out-of-pocket expenses for healthcare services. The study makes a significant contribution to the empirical modeling of patients’ behavioral responses to hospitable healthcare environments.     

The Organization of Innovation Brokers: An International Review

Research on networks of innovation has typically focused on relationships of competition and collaboration between firms in the network, sometimes extending the analysis to sources of new ideas such as universities. More recently, attention has been paid to the activities of intermediaries in such networks, which facilitate the innovation process, which are positioned between the sources and users of innovations. This paper focuses on the organization of a distinctive type of intermediary, which we have defined as an innovation broker, by providing an analysis of 10 case studies of organizations dedicated to innovation broking from around the world. Innovation brokers in our definition are organizations that are founded especially to undertake an intermediary role, rather than performing that role as a by-product of their principal activities. The results of this analysis suggest that the key role played by innovation brokers in the innovation process is the independent validation of new ideas, thereby facilitating diffusion. In order to carry out this task, innovation brokers are organized on a not-for-profit basis, typically as a public–private partnership. The paper concludes by discussing the implications of the findings for innovation theory and research in networks of innovation.