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71.
72.
党的十八届四中全会通过的《中共中央关于全面推进依法治国若干重大问题的决定》为全面推进依法治国作出重大部署.我们不仅要从历史和全局的高度学习贯彻十八届四中全会精神和《决定》内涵,以实事求是的精神全面推进依法治国,同时又要以依法治国方针为指导,全面推进高职教育事业健康快速发展.  相似文献   
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Objective: With a high prevalence of chronic kidney disease (CKD) in type 2 diabetes (T2DM) in Thailand, the appropriate treatment for the patients has become a major concern. This study aimed to evaluate long-term cost-effective of dipeptidyl peptidase-4 (DPP-4) inhibitor monothearpy vs sulfonylurea (SFU) monotherapy in people with T2DM and CKD.

Methods: A validated IMS CORE Diabetes Model was used to estimate the long-term costs and outcomes. The efficacy parameters were identified and synthesized using a systematic review and meta-analysis. Baseline characteristics and cost parameters were obtained from published studies and hospital databases in Thailand. Costs were expressed in 2014?US Dollars. Outcomes were presented as an incremental cost-effectiveness ratio (ICER). One-way and probabilistic sensitivity analyses were performed to estimate parameter uncertainty.

Results: From a societal perspective, treatment with DPP-4 inhibitors yielded more quality-adjusted life years (QALYs) (0.024) at a higher cost (>66,000 Thai baht (THB) or >1,829.27 USD) per person than SFU, resulting in the ICER of >2.7 million THB/QALY (>74,833.70 USD/QALY). The cost-effectiveness results were mainly driven by differences in HbA1c reduction, hypoglycemic events, and drug acquisition cost of DPP-4 inhibitors. At the ceiling ratio of 160,000 THB/QALY (4,434.59 USD/QALY), the probability that DPP-4 inhibitors are cost-effective compared to SFU was less than 10%.

Conclusions: Compared to SFU, DPP-4 inhibitor monotherapy is not a cost-effective treatment for people with T2DM and CKD in Thailand.  相似文献   
75.
2005年以来英语专业四级考试完形填空试题的考点效度比以前有所提高,但句子层次考点数量仍然偏高。教师在教学过程中应注重培养学生的语篇理解能力和逻辑分析能力,提高学生的语言综合运用能力。  相似文献   
76.
茅台酒的发展历程,也是我国酒文化的发展历程,在不断的传承和发展中逐渐形成了茅台酒特有的口感和独特的文化品牌价值,更为其赢得了国酒的美誉,雄踞高档白酒的顶端。通过对茅台进行SWOT分析,可以发现茅台发展也面临一定的挑战,基于4P战略为茅台提出营销策略。  相似文献   
77.
This paper analyses the extent to which the level of bank competition influences monetary policy transmission. Using a large panel dataset of 978 banks from 55 countries, and employing the Lerner index model as a measure of market structure, our results show that an increase in banking sector competition weakens the effectiveness of monetary policy on bank lending. The findings are robust to a broad array of sensitivity checks including control of alternative measurements of the Lerner index, different samples and different methodological specifications. By extension, these results have important policy implications for regulators in assessing the effectiveness of monetary policy transmission mechanisms.  相似文献   
78.
The Federal Home Loan Bank (FHLB) System is a large cooperatively owned government‐sponsored liquidity facility that lends predominately to U.S. depository institutions. This paper documents the significant role played by the FHLB System at the outset of the recent financial crisis and provides evidence on the uses of FHLB funding by member banks and thrifts during that time. We then compare lending activity by the FHLB System and the Federal Reserve during 2007 and 2008, discuss the types of institutions seeking government‐sponsored liquidity at various times, and identify the trade‐offs faced by borrowers eligible to tap liquidity from both facilities.  相似文献   
79.
Abstract

Subsequent to the first-ever Public Company Accounting Oversight Board (PCAOB) censure of a US Big 4 firm (Deloitte) in December 2007, there were two other PCAOB US Big 4 firm censures as of 2016 year-end. We examine whether these two post-2007 PCAOB censures of US Big 4 firms conveyed new information to the audit market. For both censures, we find little or no evidence of any change in the factual audit quality of the censured firm over a three-year window surrounding the censure. Our findings suggest that the quality control deficiencies (identified during inspection of specific audit engagements) that triggered the PCAOB censure were isolated occurrences rather than systemic to the firm at large, i.e., the censures do not imply an impairment in the US Big 4 firm's overall factual audit quality. We also find that the negative response of investors and audit committees documented in prior research for the 2007 Deloitte censure disappeared for the later US Big 4 firm censures. Given that the PCAOB inspects (and can censure) non-US auditors who audit US-listed foreign companies, our findings are of potential interest to regulators, investors and audit committees outside the US.  相似文献   
80.
随着我国汽车行业的迅猛发展,汽车产品和品牌日益丰富,客户需求也日益提高,我国汽车产业的格局发生了巨大的变化。目前,我国汽车营销正处于"大洗牌"的时期,在这一时期中,为了寻求发展,很多汽车企业都引入了市场营销中广为流传的4C理论。但是随着这一理论的广泛引用,很多内容已经不适用于当今汽车营销的发展。因此,需要对这一理论进行完善。在这一背景下,笔者提出了汽车营销的6C模型。  相似文献   
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