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Aims: Depression is the most frequent comorbidity reported among patients with rheumatoid arthritis (RA). Comorbid depression negatively impacts RA patients’ health-related quality-of-life, physical function, mental function, mortality, and experience of pain and symptom severity. The objective of this study was to assess healthcare utilization, expenditures, and work productivity among patients with RA with or without depression.

Materials and methods: Data from adult patients who had at least two visits each related to RA and depression over a 1-year period were extracted from the Truven Health MarketScan research databases. Outcomes comprised healthcare resource utilization, work productivity loss, and direct healthcare costs comparing patients with RA with depression (n?=?3,478) vs patients with RA without depression (n?=?43,222).

Results: Patients with RA and depression had a significantly greater relative risk of hospitalization and number of all-cause and RA-related hospitalizations, utilization of emergency services, days spent in the hospital, physician visits, and RA-related surgeries compared with RA patients without depression. Patients with RA and depression had a higher risk of and experienced more events and days of short-term disability compared with patients without depression. The incremental adjusted annual all-cause and RA-related direct costs were $8,488 (95% CI = $6,793–$10,223) and $578 (95% CI = –$98–$1,243), respectively, when comparing patients with RA and depression vs RA only.

Limitations: The current analysis is subject to the known limitations of retrospective studies based on administrative claims data.

Conclusions: This study suggested increased healthcare utilization, work productivity loss, and economic burden among RA patients due to comorbid depression. These findings emphasize the importance of managing depression and including depression as a factor when devising treatment algorithms for patients with RA.  相似文献   
3.
军民融合产业园区高质量发展对于推进军民深度融合、在全国形成可复制可推广经验具有重要意义。军民融合协同创新通过促进新知识涌现、推进新产业集聚发展,最终汇聚经济发展新动能,驱动园区高质量发展。在提出军民融合协同创新驱动园区高质量发展的机理与组织框架基础上,将发展模式归纳为以分享经济为背景的资源共享模式、以新型研发机构为核心的第三方模式、以产业联盟为核心的产业链拓展模式和以交易平台为核心的“PPP”模式,最后提出相关对策建议。  相似文献   
4.
企业创新是国家经济可持续增长的关键,受到管理层意愿的影响,因而需要对内部经营者的权力进行制衡。以2010-2018年我国A股上市公司为研究样本,实证检验管理层权力制衡强度对企业创新投资的影响,以及不同债务约束情境下高商业信用配置、高负债水平的调节效应,此外,还考察了产权性质的差异化影响。研究表明,管理层权力制衡强度越大,企业创新投资水平越高;高商业信用强化了该促进作用,而高负债水平弱化了该促进作用。进一步研究发现,管理层权力制衡强度与企业创新投资的关系在民企中更显著;国企能够更好地获得和运用商业信用,使其高商业信用对该关系的强化效应更显著;民企具有更强的债务约束,其高负债水平对该关系的弱化效应更明显。  相似文献   
5.
Organizations increasingly depend on employee efforts to innovate. However, the quality of relationships between leaders and employees may affect the recognition that employees receive for their innovative work behaviors. Drawing from a social cognition perspective, we tested a model in which leader–member exchange (LMX) moderates the impact of employee innovative work behavior on supervisory ratings of employee performance. Results from two multisource studies combining self, colleague, and supervisor ratings consistently showed that employees receive more favorable performance ratings by engaging in innovative work behavior when they have high‐quality LMX relationships. Moreover, we found that this interactive relationship was mediated by leader perceptions of innovative employee efforts, providing support for a moderated mediation model. Implications for the literatures on performance appraisal, LMX, and innovation are discussed.  相似文献   
6.
This article examines the role of national culture, measured by conflict avoidance, on the relationship between leader–member exchange (LMX) and individual employee voice. Using data collected from automotive industry employees in the United States and Korea, the findings show that conflict avoidance is negatively related to employee voice and also moderates the relationship between LMX and employee voice in the Korean sample. In particular, the relationship between LMX and voice becomes less positive when conflict avoidance is high. On the other hand, conflict avoidance does not have a direct effect on employee voice as well as an interactive effect with LMX on employee voice in the U.S. sample. This study, therefore, highlights the importance of the national culture in the comparative study of employee voice.  相似文献   
7.
We use several U.S. and euro‐area surveys of professional forecasters to estimate a dynamic factor model of inflation featuring time‐varying uncertainty. We obtain survey‐consistent distributions of future inflation at any horizon, both in the U.S. and the euro area. Equipped with this model, we propose a novel measure of the anchoring of inflation expectations that accounts for inflation uncertainty. Our results suggest that following the Great Recession, inflation anchoring improved in the United States, while mild de‐anchoring occurred in the euro area. As of our sample end, both areas appear to be almost equally anchored.  相似文献   
8.
We provide evidence on how corporate bond investors react to a change in yields, and how this behaviour differs in times of market‐wide stress. We also investigate ‘reaching for yield’ across investor types, as well as providing insights into the structure of the corporate bond market. Using proprietary sterling corporate bond transaction data, we show that insurance companies, hedge funds and asset managers are typically net buyers when corporate bond yields rise. Dealer banks clear the market by being net sellers. However, we find evidence for this behaviour reversing in times of stress for some investors. During the 2013 ‘taper tantrum’, asset managers were net sellers of corporate bonds in response to a sharp rise in yields, potentially amplifying price changes. At the same time, dealer banks were net buyers. Finally, we provide evidence that insurers, hedge funds and asset managers tilt their portfolios towards higher risk bonds, consistent with ‘reaching for yield’ behaviour.  相似文献   
9.
农机社会化服务采纳、禀赋差异与农村经济相对贫困缓解   总被引:1,自引:0,他引:1  
进入以缓解相对贫困为重点的后扶贫时代,农村经济相对贫困问题仍不容忽视。农机社会化服务作为小农户与现代农业有机衔接的桥梁,对于推进乡村振兴战略和脱贫攻坚有序衔接具有重要作用。文章讨论的核心议题是农机社会化服务采纳如何缓解农村经济相对贫困,并尝试建立了“农机社会化服务采纳——禀赋差异缩小——农村经济相对贫困缓解”的理论分析框架。为此,文章首先对农机社会化服务采纳影响农村经济相对贫困的作用机制进行了理论分析,然后利用2750份河南省农户问卷调查数据,运用Logit模型,实证检验农机社会化服务采纳对农村经济相对贫困的影响,并通过替代核心自变量和变更样本的方法进行稳健性检验,运用PSM模型和IVProbit模型以及ERM模型进行内生性讨论,最后通过中介效应模型对其作用机制进行验证。结果表明,农机社会化服务采纳对农村经济相对贫困具有显著负向影响,缓解了农村经济相对贫困。考虑内生性后,结论仍具有稳健性。进一步的机制验证发现,农机社会化服务采纳通过缩小劳动力禀赋差异和技术禀赋差异,缓解农村经济相对贫困,劳动力禀赋差异缩小和技术禀赋差异缩小的中介效应占比分别为21.22%和7.36%。可见,应将完善农机社会化服务供需体系纳入农户相对贫困治理机制考虑范畴,引导农户从传统家庭化生产转向现代社会化生产,扩大农机社会化服务采纳范围;同时完善就业服务等相关配套体系以吸纳释放的弱劳动力,促进农户收入增长,缓解农村经济相对贫困。  相似文献   
10.
我们选择市场经济,是因为迄今为止的历史证明市场经济是可以富其国裕其民的。然而,我们所要的富裕,不是少数人的富裕,而是人民群众的共同富裕。不仅要富裕,而且必须是共同富裕的市场经济。因此,我们必须对市场经济进行改造,创造出我们自己的市场经济,这就是有中国特色的社会主义市场经济。该文遵循实事求是和历史唯物主义的原则,从市场经济旨在提高效率、社会主义则是坚持党的领导和社会公正、路径依赖和历史沿革体现了市场经济的中国特色等四个方面论证了中国共产党领导全国人民选择社会主义市场经济是一个具有历史必然性的伟大选择。这样的选择使得中国经济发展和人民富裕。  相似文献   
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