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1.
Aims: Depression is the most frequent comorbidity reported among patients with rheumatoid arthritis (RA). Comorbid depression negatively impacts RA patients’ health-related quality-of-life, physical function, mental function, mortality, and experience of pain and symptom severity. The objective of this study was to assess healthcare utilization, expenditures, and work productivity among patients with RA with or without depression.

Materials and methods: Data from adult patients who had at least two visits each related to RA and depression over a 1-year period were extracted from the Truven Health MarketScan research databases. Outcomes comprised healthcare resource utilization, work productivity loss, and direct healthcare costs comparing patients with RA with depression (n?=?3,478) vs patients with RA without depression (n?=?43,222).

Results: Patients with RA and depression had a significantly greater relative risk of hospitalization and number of all-cause and RA-related hospitalizations, utilization of emergency services, days spent in the hospital, physician visits, and RA-related surgeries compared with RA patients without depression. Patients with RA and depression had a higher risk of and experienced more events and days of short-term disability compared with patients without depression. The incremental adjusted annual all-cause and RA-related direct costs were $8,488 (95% CI = $6,793–$10,223) and $578 (95% CI = –$98–$1,243), respectively, when comparing patients with RA and depression vs RA only.

Limitations: The current analysis is subject to the known limitations of retrospective studies based on administrative claims data.

Conclusions: This study suggested increased healthcare utilization, work productivity loss, and economic burden among RA patients due to comorbid depression. These findings emphasize the importance of managing depression and including depression as a factor when devising treatment algorithms for patients with RA.  相似文献   
2.
已有文献认为失败学习对企业绩效具有重要作用,但失败学习通过何种途径促进企业绩效提升的研究并不完善。基于失败学习理论,引入资源拼凑和机会识别作为中介变量,构建失败学习影响企业绩效的多路径模型,探索失败学习对企业绩效的驱动路径及内在机理。实证结果表明:失败学习对企业绩效具有显著积极作用,资源拼凑和机会识别分别在失败学习与企业绩效之间起中介作用,资源拼凑和机会识别在失败学习对企业绩效驱动过程中存在链式中介作用,战略柔性能够强化资源拼凑与企业绩效之间的关系,并正向调节资源拼凑的中介作用。研究结论拓展了失败学习对企业绩效的影响路径,对企业复苏和成长具有重要启示。  相似文献   
3.
We develop a behavioral asset pricing model in which agents trade in a market with information friction. Profit‐maximizing agents switch between trading strategies in response to dynamic market conditions. Owing to noisy private information about the fundamental value, the agents form different evaluations about heterogeneous strategies. We exploit a thin set—a small sub‐population—to point identify this nonlinear model, and estimate the structural parameters using extended method of moments. Based on the estimated parameters, the model produces return time series that emulate the moments of the real data. These results are robust across different sample periods and estimation methods.  相似文献   
4.
We propose a Bayesian model to quantify the uncertainty associated with the payments per claim incurred (PPCI) algorithm. Based on the PPCI algorithm, two submodels are proposed for the number of reported claims run-off triangle and the PPCI run-off triangle, respectively. The model for the claims amount is then derived from the two submodels under the assumption of independence between the number of incurred claims and the PPCI. The joint likelihood of the number of reported claims and claims amount is derived. The posterior distribution of parameters is estimated via the Hamiltonian Monte Carlo (HMC) sampling approach. The Bayesian estimator, the process variance, the estimation variance, and the predictive distribution of unpaid claims are also studied. The proposed model and the HMC inference engine are applied to to an empirical claims dataset of the WorkSafe Victoria to estimate the unpaid claims of the doctor benefit. The Bayesian modeling procedure is further refined by including a preliminary generalized linear model analysis. The results are compared with those in a PwC report. An alternative model is compared with the proposed model based on various information criteria.  相似文献   
5.
以2009-2018年中国创业板公司为样本,考察公司上市前的专利突击现象,检验专利突击行为对专利质量和经营业绩的影响.研究发现:第一,创业板上市公司IPO前存在明显的专利突击现象,具体表现为专利申请数量在上市前激增,在上市后增长停滞;第二,创业板公司专利突击行为降低了专利质量和上市后的长期经营业绩;第三,相较于发明专利,非发明专利的上市前突击现象更明显;第四,2014年证监会关于创业板上市公司在招股说明书中对专利信息披露的有关规定改变了公司专利申请策略,申请时间前移,上市前已申请但未授权的专利占比降低.最后,企业突击申请专利会使投资者高估公司价值,从而损害投资者利益.研究结论有利于理解我国"专利泡沫"现象的制度诱因,对完善创业板制度和实现注册制转型具有借鉴意义.  相似文献   
6.
周霞  王楠  毕添宇  陈震  季鹏 《城市发展研究》2021,28(6):中插1-中插7
国家级新区是国家区域空间生产策略的体现,新时期高质量发展对其空间优化提出新要求.基于产城融合、区域协同与双效提升的高质量发展目标体系,构建国家级新区空间优化效果—效率双评价四分图模型,比较分析浦东、滨海等6个国家级新区2011~2017年空间优化水平.研究发现:(1)6个国家级新区空间优化水平整体呈现马太效应,低效果—低效率的新区间差距呈扩大趋势.(2)国家级新区空间优化水平存在南高北低的区域差异,南部4个新区中,2010年前成立的新区空间优化水平更高.(3)国家级新区空间优化效果与效率总体均值呈现类雁形与"乀"形变化.从以动态评价赋能精准施策、以绿色创新推动产城融合、以开放协调带动新区合作、以双效提升引导差异化发展等方面提出国家级新区空间优化的建议.  相似文献   
7.
In the context of personal income tax (PIT) reform in China in 2018, this paper examines some of the major issues of concern regarding the reform and income distribution. Using the China Personal Income Tax Micro‐simulation model, the paper compares the differences between the 2011 and 2018 PIT systems, and finds that residents relying on different income sources may face a large degree of real tax rate change. Once the tax system is altered to PIT 2018, the coverage of PIT for wage earners will decrease from 46.9 to 23.4 percent, the income redistributive effect will drop from 1.95 to 1.22 percent and the PIT's role in fiscal revenue will also be negatively affected. Nevertheless, if individual income continues to grow, the share of PIT in fiscal revenue is expected to return to the 2018 level in 2022, but its income redistribution function is difficult to recover in the short term. The paper finds that the effect of PIT on income distribution depends on the tax structure. Gradual transition to an “entirely comprehensive” tax system when conditions are appropriate will achieve better income redistribution results at a lower average tax rate.  相似文献   
8.
服务是高职院校的第一宗旨,而社会服务能力的高低关键在于示范院校师资队伍建设。该文从广东农工商职业技术学院社会服务能力的实际情况出发,分析了该院师资队伍建设存在的问题,认为,首先应通过体制创新,提高教师社会服务意识;其次通过不同途径打造"双师型"教师团队,从而提升教师社会服务能力。  相似文献   
9.
Labor unemployment insurance reduces unemployment concerns. We argue that these benefits moderate incentives to smooth earnings to reduce employees’ concerns about unemployment risk. Using exogenous variations in unemployment insurance benefits, we find evidence consistent with this argument. We also find that the link between unemployment insurance benefits and income smoothing is stronger when there is higher unemployment risk and when the firm is likely to employ more low-wage workers, who find unemployment insurance benefits especially useful. Our paper contributes to the literature by showing that public policy decisions such as unemployment insurance have significant, albeit probably unintended, externalities on corporate financial reporting.  相似文献   
10.
Following the animal spirits theory proposed by Akerlof and Shiller, this article contributes to behavior economics by investigating the possibility of using auction sales data to capture evidence of irrational exuberance in the housing market. Using the monthly percentages of residential property auction sales for Auckland, Wellington and Christchurch regions in New Zealand from 2006 to 2015, and the exuberance testing method proposed by Phillips, Shi and Yu, we find that animal spirits have been developing in the Auckland housing market since 2013, but not in other regions. When compared to the results based on price‐to‐rent ratios, auction sales provide more meaningful results for identifying market‐wide irrational exuberance at an early stage. The causality test on price‐to‐rent ratios and auction sales volume shows that asset prices and animal spirits influence each other in the short run. In the long run, prices have significant effect on animal spirits, but not vice versa.  相似文献   
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