阿莫西林克拉维酸钾片含量测定方法的改进

为解决实际应用中克拉维酸钾峰与后相邻杂质的分离度达不到要求的问题,建立了一种同时测定阿莫西林克拉维酸钾片中阿莫西林和克拉维酸钾含量的新方法,采用反相高效液相色谱法(RP-HPLC),Ultimate AQ-C_(18)色谱柱(4.6mm×250 mm,5μm),以pH值为4.4的0.05 mol/L磷酸二氢钠缓冲液为流动相,柱温为35℃,流速为1.0mL/min,检测波长为220nm。结果表明:阿莫西林和克拉维酸钾两主峰与相邻杂质得到完全基线分离,分离度大于1.5;克拉维酸钾对照品溶液质量浓度为0.050 0~0.500 1mg/mL时与峰面积的线性关系良好(r=0.999 8),平均回收率(n=9)为100.14%,RSD值为0.24%;阿莫西林对照品溶液质量浓度为0.100 0~1.000 1mg/mL时与峰面积的线性关系良好(r=0.999 9),平均回收率(n=9)为100.45%,RSD值为0.17%。与原有的《中华人民共和国药典》方法相比,新的阿莫西林克拉维酸钾片含量测定方法专属性好,准确度高,操作简便快捷,结果可靠,可作为一种质量控制方法。     

A Statistical Model to Investigate the Reproducibility Rate Based on Replication Experiments

The reproducibility crisis, that is, the fact that many scientific results are difficult to replicate, pointing to their unreliability or falsehood, is a hot topic in the recent scientific literature, and statistical methodologies, testing procedures and p‐values, in particular, are at the centre of the debate. Assessment of the extent of the problem–the reproducibility rate or the false discovery rate–and the role of contributing factors are still an open problem. Replication experiments, that is, systematic replications of existing results, may offer relevant information on these issues. We propose a statistical model to deal with such information, in particular to estimate the reproducibility rate and the effect of some study characteristics on its reliability. We analyse data from a recent replication experiment in psychology finding a reproducibility rate broadly coherent with other assessments from the same experiment. Our results also confirm the expected role of some contributing factor (unexpectedness of the result and room for bias) while they suggest that the similarity between original study and the replica is not so relevant, thus mitigating some criticism directed to replication experiments.     

创新战略下的英国研发组织创新——Catapults的组织管理模式研究

Catapults（弹射中心）作为一种新型研发组织形式，在英国创新发展战略的实施中扮演着重要角色。精准的组织功能定位、高效的组织管理运作模式和紧密的网络化组织关系，是Catapults组织管理模式创新的重要三大重要内容。为我国新型研发机构的培育和发展提供了良好的参考样本。     

The Impact of Public Expenditure and International Trade on Agricultural Productivity in China

The “industry nurturing agriculture” reforms and World Trade Organization accession led to dramatic growth in public expenditure and international trade in China’s agricultural sector. This article aims to estimate the effects of public expenditure and trade on agricultural productivity in China for 2004–2015. A semi-parametric production function with shape constraints is introduced to derive more accurate productivity before the productivity determinants are analyzed with an emphasis on public expenditure and trade. The empirical result shows that public expenditure and exports can effectively improve agricultural productivity, while imports have no significant effects. Policy implications are discussed in the context of supply-side reforms.     

The effect of place attachment of geographical indication agricultural products on repurchase intention

[Objective] This study aims to investigate how place attachment and the quality of experience affect consumers' intention to repurchase Geographical Indication (GI) agricultural products. [Methodology] Based on the special functional value and symbolic meaning of GI agricultural products, we constructed a five-dimensional model of place attachment for GI agricultural products consumers. Expanding on the original two-dimensional place attachment model, we introduced three connection concepts: nature, society, and emotion. We also combined this model with the quality of experience model and consumer purchase intention model to form a research model of repurchase intention for GI agricultural products. A questionnaire survey was used to collect data (n = 340), and a partial least squares structural equation model was used to test the empirical evidence. [Research results] (1) Place attachment to Geographical Indication agricultural products significantly affects the quality of experience. (2) Quality of experience significantly affects consumer trust and repurchase intention. (3) Consumer trust significantly affects repurchase intention. (4) There is a mediating effect of experience quality between place attachment and repurchase intention; there is a mediating effect of trust in the relationship between quality of experience and repurchase intention. (5) There is a chain mediating effect of “place attachment→quality of experience→consumer trust→repurchase intention” in the model.     

Entanglements in multispecies voluntourism: conservation and Utila's affect economy

Abstract

Through a case study of conservation voluntourism this article brings together critical political ecology, multispecies ethnography, and studies of humanitarian tourism to advance a political ecology of multispecies conservation voluntourism. The article presents multispecies conservation voluntourism as a field that produces and is produced by an “affect economy”, or an economy based on the exchange or trade in the relational. Since the mid-1990s, life on Utila, Honduras, a popular discount backpacker scuba destination located along the Mesoamerican Barrier Reef, has been deeply transformed by the growth of dive tourism, the ecological destruction it has produced, and now the conservation voluntourism industry emerging in its wake. Seventy percent of Utila is comprised of mangroves and associated wetlands, home to several endangered and endemic species. Using examples of whale shark tourism, lionfish hunts, and iguana tracking, this article shows how conservation organizations operate as affect generators, enabling the privilege of engaging in multispecies encounters. Engaging in multispecies conservation voluntourism produces value in the form of cultural capital which is then exchanged for material outcomes by volunteers in the global economy; at the same time, this form of voluntourism obscures local relationships to nature and alters multispecies assemblages from past configurations.     

Local tax interaction and endogenous spatial weights based on quality of life

This paper studied the role of municipal quality of life as a driver of strategic tax interactions among local governments. A number of studies point out the existence of strategic interactions using spatial econometric models in which the spatial weights are mostly based on non-economic criteria or basic economic variables such as per capita gross domestic product (GDP). We propose the more sophisticated well-being indicator of municipal quality of life as the driver for these interactions. To deal with the potential endogeneity, we rely on instrumental variable estimators. The empirical analysis focuses on the main local tax in Spain (property) and on municipalities with more than 50,000 inhabitants, and it confirms the relevance of differentials in quality of life for the understanding of tax choices.     

Exploring job crafting: Diagnosing and responding to the ways employees adjust their jobs

Recent research has developed an in-depth understanding of how workers change their jobs on their own to improve their performance and well-being, a process called job crafting. This research suggests that managers, coworkers, and organizations need a better understanding of how to manage job crafting to capitalize on its benefits and reduce costs. This article will help organizations diagnose the occurrence of job crafting, recognize the differences between goal-oriented approaches to job crafting as opposed to withdrawal-oriented avoidance job crafting, and identify the seven specific types of job crafting: work role expansion, social expansion, work role reduction, work organization, adoption, metacognition, and withdrawal. We conclude with recommendations for managers, coworkers, and organizations on how to diagnose and manage job crafting.     

War and economy. Rediscovering the eighteenth-century military entrepreneur

Abstract

The detrimental effects traditionally assigned to warfare in the development of pre-industrial economies have obscured the prominent role that military entrepreneurs played in economic development in this period. Historiography minimises the extent to which war and the concomitant strengthening of the central state provided a whole new range of opportunities for capital investment, a tendency that has been strengthened by the paradigm of Redlich’s ‘decline of the soldier-entrepreneur’ and the technological determinism of the debate on the Military Revolution among others. The aim of this introduction is to look into the background of this relative lack of interest and to reaffirm the mutual dependence of eighteenth-century state-formation and the business of war.     

Resource Dependence and Network Relations: A Test of Venture Capital Investment Termination in China

This study examines how venture capital (VC) firms terminate investments in an emerging economy context. We contend that due to the weak institutional environment, it is appropriate to draw on insights from power and social relation perspectives for a better understanding of the phenomenon. Specifically, we argue that a termination decision hinges on not only the dependence relationship between a VC firm and its portfolio companies, but also the social relationships among VC firms. Event history analyses of approximately 12,000 VC deals made in China between 2001 and 2012 reveal that when a VC firm has a greater number of investments in an industry, it is more likely to terminate investments on a portfolio company in that industry. Moreover, such effect on termination is moderated by the focal VC's embeddedness with its syndicate partners and collaboration opportunities with other VC firms outside the immediate access of the syndicate partners. Our study sheds light on research on VC decision making in emerging markets by integrating insights from resource dependence relationships and interorganizational network characteristics.